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  1. Acute respiratory distress syndrome (ARDS) is characterised by diffuse alveolar damage and is frequently complicated by pulmonary hypertension (PH). Multiple factors may contribute to the development of PH in ...

    Authors: Donal Ryan, Stephen Frohlich and Paul McLoughlin
    Citation: Annals of Intensive Care 2014 4:28
  2. The features of early-phase acute respiratory distress syndrome (ARDS) are leakage of fluid into the extravascular space and impairment of its reabsorption, resulting in extravascular lung water (EVLW) accumul...

    Authors: Takashi Tagami, Toshiaki Nakamura, Shigeki Kushimoto, Ryoichi Tosa, Akihiro Watanabe, Tadashi Kaneko, Hidetada Fukushima, Hiroshi Rinka, Daisuke Kudo, Hideaki Uzu, Akira Murai, Makoto Takatori, Hiroo Izumino, Yoichi Kase, Ryutarou Seo, Hiroyuki Takahashi…
    Citation: Annals of Intensive Care 2014 4:27
  3. Thrombocytopenia is common in the intensive care unit. Potential mechanisms and etiologies behind this phenomenon are multiple and often entangled. We assessed the effect of a systematic approach, using routin...

    Authors: Nadiejda Antier, Jean-Pierre Quenot, Jean-Marc Doise, Robin Noel, Emmanuel Demaistre and Hervé Devilliers
    Citation: Annals of Intensive Care 2014 4:24
  4. In the later stages of circulatory shock, monitoring should help to avoid fluid overload. In this setting, volume expansion is ideally indicated only for patients in whom the cardiac index (CI) is expected to ...

    Authors: Thieme Souza Oliveira Nunes, Renata Teixeira Ladeira, Antônio Tonete Bafi, Luciano Cesar Pontes de Azevedo, Flavia Ribeiro Machado and Flávio Geraldo Rezende Freitas
    Citation: Annals of Intensive Care 2014 4:25
  5. High inspiratory oxygen concentrations are frequently administered in ventilated patients in the intensive care unit (ICU) but may induce lung injury and systemic toxicity. We compared beliefs and actual clini...

    Authors: Hendrik JF Helmerhorst, Marcus J Schultz, Peter HJ van der Voort, Robert J Bosman, Nicole P Juffermans, Evert de Jonge and David J van Westerloo
    Citation: Annals of Intensive Care 2014 4:23
  6. Prognostic abilities of medical parameters, which are scoring systems, measurements and biomarkers, are important for stratifying critically ill patients. Indocyanine green plasma disappearance (ICG-PDR) is an...

    Authors: Bernhard Zoller, Katharina Spanaus, Rahel Gerster, Mario Fasshauer, Paul A Stehberger, Stephanie Klinzing, Athanasios Vergopoulos, Arnold von Eckardstein and Markus Béchir
    Citation: Annals of Intensive Care 2014 4:19
  7. The death of a loved one is often an ordeal and a tragedy for those who witness it, as death is not merely the end of a life, but also the end of an existence, the loss of a unique individual who is special an...

    Authors: Cédric Daubin, Lise Haddad, Dominique Folscheid, Alexandre Boyer, Ludivine Chalumeau-Lemoine, Olivier Guisset, Philippe Hubert, Jérôme Pillot, René Robert and Didier Dreyfuss
    Citation: Annals of Intensive Care 2014 4:17
  8. Despite advances in supportive care, moderate-severe acute respiratory distress syndrome (ARDS) is associated with high mortality rates, and novel therapies to treat this condition are needed. Compelling pre-c...

    Authors: Kathleen D Liu, Jennifer G Wilson, Hanjing Zhuo, Lizette Caballero, Melanie L McMillan, Xiaohui Fang, Katherine Cosgrove, Carolyn S Calfee, Jae-Woo Lee, Kirsten N Kangelaris, Jeffrey E Gotts, Angela J Rogers, Joseph E Levitt, Jeanine P Wiener-Kronish, Kevin L Delucchi, Andrew D Leavitt…
    Citation: Annals of Intensive Care 2014 4:22
  9. Platelet activation and consumption are common in critically ill patients and are associated with poorer prognosis. Mean platelet volume is a simple surrogate for platelet activation, with higher MPV being ass...

    Authors: Fernando G Zampieri, Otavio T Ranzani, Viviane Sabatoski, Heraldo Possolo de Souza, Hermes Barbeiro, Luiz Monteiro Cruz da Neto, Marcelo Park and Fabiano Pinheiro da Silva
    Citation: Annals of Intensive Care 2014 4:20
  10. The influenza H1N1 epidemics in 2009 led a substantial number of people to develop severe acute respiratory distress syndrome and refractory hypoxemia. In these patients, extracorporeal membrane oxygenation wa...

    Authors: Christian Richard, Laurent Argaud, Alice Blet, Thierry Boulain, Laetitia Contentin, Agnès Dechartres, Jean-Marc Dejode, Laurence Donetti, Muriel Fartoukh, Dominique Fletcher, Khaldoun Kuteifan, Sigismond Lasocki, Jean-Michel Liet, Anne-Claire Lukaszewicz, Hervé Mal, Eric Maury…
    Citation: Annals of Intensive Care 2014 4:15
  11. Daily sedative interruption and intermittent sedation are effective in abbreviating the time on mechanical ventilation. Whether one is superior to the other has not yet been determined. Our aim was to compare ...

    Authors: Antonio Paulo Nassar Junior and Marcelo Park
    Citation: Annals of Intensive Care 2014 4:14
  12. The optimum dosage regimen for cotrimoxazole in the treatment of life threatening infections due to susceptible organisms encountered in critically ill patients is unclear despite decades of the drug’s use. Th...

    Authors: Glen R Brown
    Citation: Annals of Intensive Care 2014 4:13
  13. We studied a score for assessing basic transthoracic echocardiography (TTE) skills exhibited by residents who examined critically ill patients receiving mechanical ventilation.

    Authors: Mathieu Jozwiak, Xavier Monnet, Raphaël Cinotti, Fréderic Bontemps, Jean Reignier and Guillaume Belliard
    Citation: Annals of Intensive Care 2014 4:12
  14. Earlobe arterialized capillary blood gas analysis can be used to estimate arterial gas content and may be suitable for diagnosis and management of critically ill patients. However, its utility and applicabilit...

    Authors: Sergi Vaquer, Jordi Masip, Gisela Gili, Gemma Gomà, Joan Carles Oliva, Alexandre Frechette, Simon Evetts, Thais Russomano and Antonio Artigas
    Citation: Annals of Intensive Care 2014 4:11
  15. ICU patients frequently undergo chest radiographs (CXRs). The diagnostic and therapeutic efficacy of routine CXRs are now known to be low, but the discussion regarding specific indications for CXRs in critical...

    Authors: Martijn Tolsma, Tom A Rijpstra, Marcus J Schultz, Paul GH Mulder and Nardo JM van der Meer
    Citation: Annals of Intensive Care 2014 4:10
  16. Post-cardiac arrest hypocapnia/hypercapnia have been associated with poor neurological outcome. However, the impact of arterial carbon dioxide (CO2) derangements during the immediate post-resuscitation period fol...

    Authors: Brian W Roberts, J Hope Kilgannon, Michael E Chansky and Stephen Trzeciak
    Citation: Annals of Intensive Care 2014 4:9
  17. OptiScanner devices, continuous glucose monitoring devices that perform automated blood draws via a central venous catheter and create plasma through centrifugation, measure plasma glucose levels through mid-i...

    Authors: Roosmarijn TM van Hooijdonk, Tineke Winters, Johan C Fischer, Edmée C van Dongen-Lases, James S Krinsley, Jean-Charles Preiser and Marcus J Schultz
    Citation: Annals of Intensive Care 2014 4:8
  18. Longstanding concerns regarding end of life in the ICU led in France to the publication of guidelines, updated in 2009, that take into account the insights provided by a recent law (Leonetti’s law) regarding p...

    Authors: René Robert, Laurence Salomon, Lise Haddad, Jean-Pierre Graftieaux, Béatrice Eon and Didier Dreyfuss
    Citation: Annals of Intensive Care 2014 4:6
  19. The aim of this study was to determine the association between 25-hydroxyvitamin D (25-OHD) levels at the onset of critical illness and the development of acute lung injury/acute respiratory distress syndrome ...

    Authors: Nicolas Barnett, Zhiguo Zhao, Tatsuki Koyama, David R Janz, Chen-Yu Wang, Addison K May, Gordon R Bernard and Lorraine B Ware
    Citation: Annals of Intensive Care 2014 4:5
  20. The Lung Injury Score (LIS) remains a commonly utilized measure of lung injury severity though the additive value of LIS to predict ARDS outcomes over the recent Berlin definition of ARDS, which incorporates s...

    Authors: Kirsten Neudoerffer Kangelaris, Carolyn S Calfee, Addison K May, Hanjing Zhuo, Michael A Matthay and Lorraine B Ware
    Citation: Annals of Intensive Care 2014 4:4
  21. Data from previous studies indicate that optimal conditions for intubation are met 120 seconds after administration of 0.15 mg.kg-1 cisatracurium (ED95 × 3) following the induction of anesthesia. The aim of this ...

    Authors: Eric Dieye, Vincent Minville, Karim Asehnoune, Claude Conil, Bernard Georges, Pierre Cougot, Olivier Fourcade and Jean-Marie Conil
    Citation: Annals of Intensive Care 2014 4:3
  22. Observational studies on mechanical ventilation (MV) show practice variations across ICUs. We sought to determine, with a case-vignette study, the heterogeneity of processes of care in ICUs focusing on mechani...

    Authors: Yên-Lan Nguyen, Elodie Perrodeau, Bertrand Guidet, Ludovic Trinquart, Jean-Christophe M Richard, Alain Mercat, Philippe Jolliet, Philippe Ravaud and Laurent Brochard
    Citation: Annals of Intensive Care 2014 4:2
  23. Lung ultrasound is a basic application of critical ultrasound, defined as a loop associating urgent diagnoses with immediate therapeutic decisions. It requires the mastery of ten signs: the bat sign (pleural l...

    Authors: Daniel A Lichtenstein
    Citation: Annals of Intensive Care 2014 4:1
  24. Intensive care unit-acquired weakness (ICUAW) is a common complication, associated with significant morbidity. Neuromuscular electrical stimulation (NMES) has shown promise for prevention. NMES acutely affects...

    Authors: Epameinondas Angelopoulos, Eleftherios Karatzanos, Stavros Dimopoulos, Georgios Mitsiou, Christos Stefanou, Irini Patsaki, Anastasia Kotanidou, Christina Routsi, George Petrikkos and Serafeim Nanas
    Citation: Annals of Intensive Care 2013 3:39
  25. The birth of the intermittent injectate-based conventional pulmonary artery catheter (fondly nicknamed PAC) was proudly announced in the New England Journal of Medicine in 1970 by his parents HJ Swan and William ...

    Authors: Paul E Marik
    Citation: Annals of Intensive Care 2013 3:38
  26. Reimbursement schemes in intensive care are more complex than in other areas of healthcare, due to special procedures and high care needs. Knowledge regarding the principles of functioning in other countries c...

    Authors: Martin-Immanuel Bittner, Maria Donnelly, Arthur RH van Zanten, Jakob Steen Andersen, Bertrand Guidet, Jose Javier Trujillano Cabello, Shane Gardiner, Gerard Fitzpatrick, Bob Winter, Michael Joannidis and Axel Schmutz
    Citation: Annals of Intensive Care 2013 3:37
  27. Transplantation brings sustainably improved quality of life to patients with end-stage organ failure. Persisting shortfall in available organs prompted French authorities and practitioners to focus on organ re...

    Authors: Olivier Lesieur, Marie-France Mamzer, Maxime Leloup, Frédéric Gonzalez, Alexandre Herbland, Brigitte Hamon, Marcel-Louis Viallard and Christian Hervé
    Citation: Annals of Intensive Care 2013 3:36
  28. Hypernatremia is common following traumatic brain injury (TBI) and occurs from a variety of mechanisms, including hyperosmotic fluids, limitation of free water, or diabetes insipidus. The purpose of this syste...

    Authors: Leif Kolmodin, Mypinder S Sekhon, William R Henderson, Alexis F Turgeon and Donald EG Griesdale
    Citation: Annals of Intensive Care 2013 3:35
  29. An intensive care unit (ICU) admission is a stressful event for the patient and the patient’s family. Several studies demonstrated symptoms of anxiety, depression, and posttraumatic stress disorder in family m...

    Authors: Fernando José da Silva Ramos, Renata Rego Lins Fumis, Luciano Cesar Pontes Azevedo and Guilherme Schettino
    Citation: Annals of Intensive Care 2013 3:34
  30. The storage duration of red blood cells transfused to critically ill patients is associated with increased morbidity and mortality. Whether the association exists between storage duration of red blood cells tr...

    Authors: David R Janz, Zhiguo Zhao, Tatsuki Koyama, Addison K May, Gordon R Bernard, Julie A Bastarache, Pampee P Young and Lorraine B Ware
    Citation: Annals of Intensive Care 2013 3:33
  31. We report a case of propofol infusion syndrome (PRIS) in a young female treated for status epilepticus. In this case, PRIS rapidly evolved to full cardiovascular collapse despite aggressive supportive care in ...

    Authors: Michael Mayette, Jeremy Gonda, Joe L Hsu and Frederick G Mihm
    Citation: Annals of Intensive Care 2013 3:32
  32. Mottling score has been reported to be a strong predictive factor during septic shock. However, the pathophysiology of mottling remains unclear.

    Authors: Hafid Ait-Oufella, Simon Bourcier, Mikael Alves, Arnaud Galbois, Jean-Luc Baudel, Dimitri Margetis, Naike Bige, Georges Offenstadt, Eric Maury and Bertrand Guidet
    Citation: Annals of Intensive Care 2013 3:31
  33. Sepsis is a leading cause of death despite appropriate management. There is increasing evidence that microcirculatory alterations might persist independently from macrohemodynamic improvement and are related t...

    Authors: Jordi Masip, Jaume Mesquida, Cecilia Luengo, Gisela Gili, Gemma Gomà, Ricard Ferrer, Jean Louis Teboul, Didier Payen and Antonio Artigas
    Citation: Annals of Intensive Care 2013 3:30
  34. As a result of reporting bias, or frauds, false or misunderstood findings may represent the majority of published research claims. This article provides simple methods that might help to appraise the quality o...

    Authors: Romain Pirracchio, Matthieu Resche-Rigon, Sylvie Chevret and Didier Journois
    Citation: Annals of Intensive Care 2013 3:29
  35. The aim of this study is to evaluate the feasibility and efficacy of Transcranial Doppler (TCD) in assessing cerebral perfusion changes in septic patients.

    Authors: Charalampos Pierrakos, Aurélie Antoine, Dimitrios Velissaris, Isabelle Michaux, Pierre Bulpa, Patrick Evrard, Michel Ossemann and Alain Dive
    Citation: Annals of Intensive Care 2013 3:28
  36. Phase III clinical trials on severe sepsis and septic shock published during the past decade have failed to reveal the superiority of any therapeutic intervention on mortality compared with evolving standards ...

    Authors: Pierre Asfar, Yann-Erick Claessens, Jacques Duranteau, Eric Kipnis, Marc Leone, Bruno Lévy and Jean-Paul Mira
    Citation: Annals of Intensive Care 2013 3:27
  37. The objective of this study was to examine the outcomes of critically ill patients who were transferred from other hospitals to a tertiary care center in Saudi Arabia as a quality improvement project.

    Authors: Asgar H Rishu, Abdulaziz S Aldawood, Samir H Haddad, Hani M Tamim, Hasan M Al-Dorzi, Ahmed Al-Jabbary, Abdullah Al-Shimemeri, Muhammad R Sohail and Yaseen M Arabi
    Citation: Annals of Intensive Care 2013 3:26
  38. Acute lung injury and the acute respiratory distress syndrome (ALI/ARDS) are characterized by pulmonary oedema, measured as extravascular lung water (EVLW). The chest radiograph (CXR) can potentially estimate ...

    Authors: Lisa M Brown, Carolyn S Calfee, James P Howard, Thelma R Craig, Michael A Matthay and Daniel F McAuley
    Citation: Annals of Intensive Care 2013 3:25
  39. Monitoring and management of intracranial pressure (ICP) and cerebral perfusion pressure (CPP) is a standard of care after traumatic brain injury (TBI). However, the pathophysiology of so-called secondary brai...

    Authors: Pierre Bouzat, Nathalie Sala, Jean-François Payen and Mauro Oddo
    Citation: Annals of Intensive Care 2013 3:23
  40. In the context of worldwide increasing antimicrobial resistance, good antimicrobial prescribing in more needed than ever; unfortunately, information available to clinicians often are insufficient to rely on. B...

    Authors: Anne-Marie Dupuy, François Philippart, Yves Péan, Sigismond Lasocki, Pierre-Emmanuel Charles, Martin Chalumeau, Yann-Eric Claessens, Jean-Pierre Quenot, Christele Gras-Le Guen, Stéphanie Ruiz, Charles-Edouard Luyt, Nicolas Roche, Jean-Paul Stahl, Jean-Pierre Bedos, Jérôme Pugin, Rémy Gauzit…
    Citation: Annals of Intensive Care 2013 3:22
  41. Biomarker-guided initiation of antibiotic therapy has been studied in four conditions: acute pancreatitis, lower respiratory tract infection (LRTI), meningitis, and sepsis in the ICU. In pancreatitis with susp...

    Authors: Jean-Pierre Quenot, Charles-Edouard Luyt, Nicolas Roche, Martin Chalumeau, Pierre-Emmanuel Charles, Yann-Eric Claessens, Sigismond Lasocki, Jean-Pierre Bedos, Yves Péan, François Philippart, Stéphanie Ruiz, Christele Gras-Leguen, Anne-Marie Dupuy, Jérôme Pugin, Jean-Paul Stahl, Benoit Misset…
    Citation: Annals of Intensive Care 2013 3:21
  42. Pharmacological interventions are commonly considered in acute respiratory distress syndrome (ARDS) patients. Inhaled nitric oxide (iNO) and neuromuscular blockers (NMBs) are used in patients with severe hypox...

    Authors: Antoine Roch, Sami Hraiech, Stéphanie Dizier and Laurent Papazian
    Citation: Annals of Intensive Care 2013 3:20
  43. Intensive care unit (ICU) patients are exposed to many sources of discomfort. Most of these are related to the patient’s condition, but ICU design or how care is organized also can contribute. The present surv...

    Authors: Véronique Lombardo, Isabelle Vinatier, Marie-Lou Baillot, Vicenta Franja, Irma Bourgeon-Ghittori, Sandrine Dray, Sylvie Jeune, Chirine Mossadegh, Jean Reignier, Bertrand Souweine and Antoine Roch
    Citation: Annals of Intensive Care 2013 3:19
  44. The prevalence of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae is increasing globally and is a major clinical concern. Between June 2008 and September 2009, 4% of patients in an intensive ...

    Authors: Nathalie Filippa, Anne Carricajo, Florence Grattard, Pascal Fascia, Faten El Sayed, Jean Pierre Defilippis, Philippe Berthelot and Gerald Aubert
    Citation: Annals of Intensive Care 2013 3:18

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