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Protecting Vulnerable Research Subjects in Critical Care Trials: Enhancing the Informed Consent Process and Recommendations for Safeguards

Although critically ill patients represent a vulnerable group of individuals, guidelines in research ethics assert that ethically acceptable research may proceed with such vulnerable subjects if additional saf...

Authors: Henry Silverman

Citation: Annals of Intensive Care 2011 1:8

Content type: Review

Published on: 13 April 2011
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Septic cardiomyopathy

Depression of left ventricular (LV) intrinsic contractility is constant in patients with septic shock. Because most parameters of cardiac function are strongly dependent on afterload, especially in this contex...

Authors: Antoine Vieillard-Baron

Citation: Annals of Intensive Care 2011 1:6

Content type: Review

Published on: 13 April 2011
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Intensive care of the cancer patient: recent achievements and remaining challenges

A few decades have passed since intensive care unit (ICU) beds have been available for critically ill patients with cancer. Although the initial reports showed dismal prognosis, recent data suggest that an inc...

Authors: Elie Azoulay, Marcio Soares, Michael Darmon, Dominique Benoit, Stephen Pastores and Bekele Afessa

Citation: Annals of Intensive Care 2011 1:5

Content type: Review

Published on: 23 March 2011
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An integrated approach for prescribing fewer chest x-rays in the ICU

Chest x-rays (CXRs) are the main imaging tool in intensive care units (ICUs). CXRs also are associated with concerns inherent to their use, considering both healthcare organization and patient perspectives. In...

Authors: Vincent Ioos, Arnaud Galbois, Ludivine Chalumeau-Lemoine, Bertrand Guidet, Eric Maury and Gilles Hejblum

Citation: Annals of Intensive Care 2011 1:4

Content type: Review

Published on: 21 March 2011
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Erythropoietin (EPO) in acute kidney injury

Erythropoietin (EPO) is a 30.4 kDa glycoprotein produced by the kidney, and is mostly well-known for its physiological function in regulating red blood cell production in the bone marrow. Accumulating evidence...

Authors: Elizabeth Moore and Rinaldo Bellomo

Citation: Annals of Intensive Care 2011 1:3

Content type: Review

Published on: 21 March 2011
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Perioperative fluid and volume management: physiological basis, tools and strategies

Fluid and volume therapy is an important cornerstone of treating critically ill patients in the intensive care unit and in the operating room. New findings concerning the vascular barrier, its physiological fu...

Authors: Mike S Strunden, Kai Heckel, Alwin E Goetz and Daniel A Reuter

Citation: Annals of Intensive Care 2011 1:2

Content type: Review

Published on: 21 March 2011
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Hemodynamic parameters to guide fluid therapy

The clinical determination of the intravascular volume can be extremely difficult in critically ill and injured patients as well as those undergoing major surgery. This is problematic because fluid loading is ...

Authors: Paul E Marik, Xavier Monnet and Jean-Louis Teboul

Citation: Annals of Intensive Care 2011 1:1

Content type: Review

Published on: 21 March 2011
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Articles

Protecting Vulnerable Research Subjects in Critical Care Trials: Enhancing the Informed Consent Process and Recommendations for Safeguards

Septic cardiomyopathy

Intensive care of the cancer patient: recent achievements and remaining challenges

An integrated approach for prescribing fewer chest x-rays in the ICU

Erythropoietin (EPO) in acute kidney injury

Perioperative fluid and volume management: physiological basis, tools and strategies

Hemodynamic parameters to guide fluid therapy

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