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  1. Patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-COV 2) and requiring intensive care unit (ICU) have a high incidence of hospital-acquired infections; however, data regarding ho...

    Authors: Nicolas Massart, Virginie Maxime, Pierre Fillatre, Keyvan Razazi, Alexis Ferré, Pierre Moine, Francois Legay, Guillaume Voiriot, Marlene Amara, Francesca Santi, Saad Nseir, Stephanie Marque-Juillet, Rania Bounab, Nicolas Barbarot, Fabrice Bruneel and Charles-Edouard Luyt
    Citation: Annals of Intensive Care 2021 11:183

    The Correction to this article has been published in Annals of Intensive Care 2022 12:4

  2. Stratifying patients with sepsis was the basis of the predisposition, infection, response and organ dysfunction (PIRO) concept, an attempt to resolve the heterogeneity in treatment response. The purpose of thi...

    Authors: T. Cardoso, P. P. Rodrigues, C. Nunes, M. Almeida, J. Cancela, F. Rosa, N. Rocha-Pereira, I. Ferreira, F. Seabra-Pereira, P. Vaz, L. Carneiro, C. Andrade, J. Davis, A. Marçal and N. D. Friedman
    Citation: Annals of Intensive Care 2021 11:180
  3. The use of awake prone position concomitant to non-invasive mechanical ventilation in acute respiratory distress syndrome (ARDS) secondary to COVID-19 has shown to improve gas exchange, whereas its effect on t...

    Authors: Davide Chiumello, Elena Chiodaroli, Silvia Coppola, Simone Cappio Borlino, Claudia Granata, Matteo Pitimada and Pedro David Wendel Garcia
    Citation: Annals of Intensive Care 2021 11:179
  4. Cardiac surgery is performed worldwide, and acute kidney injury (AKI) following cardiac surgery is a risk factor for mortality. However, the optimal blood pressure target to prevent AKI after cardiac surgery r...

    Authors: Yuki Kotani, Takuo Yoshida, Junji Kumasawa, Jun Kamei, Akihisa Taguchi, Koji Kido, Naoki Yamaguchi, Takayuki Kariya, Masato Nakasone, Noriko Mikami, Takahiro Koga, Izumi Nakayama, Mami Shibata, Tomonao Yoshida, Hiroshi Nashiki, Shinsuke Karatsu…
    Citation: Annals of Intensive Care 2021 11:178
  5. Dyspnea is common and often severe symptom in mechanically ventilated patients. Proportional assist ventilation (PAV) is an assist ventilatory mode that adjusts the level of assistance to the activity of respi...

    Authors: Côme Bureau, Maxens Decavèle, Sébastien Campion, Marie-Cécile Nierat, Julien Mayaux, Elise Morawiec, Mathieu Raux, Thomas Similowski and Alexandre Demoule
    Citation: Annals of Intensive Care 2021 11:177
  6. Fluid management in patients after subarachnoid hemorrhage (SAH) aims at the optimization of cerebral blood flow and brain oxygenation. In this study, we investigated the effects of hemodynamic management on b...

    Authors: Verena Rass, Elisa Gouvea Bogossian, Bogdan-Andrei Ianosi, Lorenzo Peluso, Mario Kofler, Anna Lindner, Alois J. Schiefecker, Lauma Putnina, Max Gaasch, Werner O. Hackl, Ronny Beer, Bettina Pfausler, Fabio Silvio Taccone and Raimund Helbok
    Citation: Annals of Intensive Care 2021 11:176
  7. The concomitant occurrence of the symptoms intravascular hypovolemia, peripheral edema and hemodynamic instability is typically named Capillary Leak Syndrome (CLS) and often occurs in surgical critical ill pat...

    Authors: Jakob Wollborn, Lars O. Hassenzahl, Daniel Reker, Hans Felix Staehle, Anne Marie Omlor, Wolfgang Baar, Kai B. Kaufmann, Felix Ulbrich, Christian Wunder, Stefan Utzolino, Hartmut Buerkle, Johannes Kalbhenn, Sebastian Heinrich and Ulrich Goebel
    Citation: Annals of Intensive Care 2021 11:175

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:27

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:28

  8. Hemodynamic instability is a frequent complication of sustained low-efficiency dialysis (SLED) treatments in the ICU. Intravenous hyperoncotic albumin may prevent hypotension and facilitate ultrafiltration. In...

    Authors: Edward G. Clark, Lauralyn McIntyre, Irene Watpool, Jennifer W. Y. Kong, Tim Ramsay, Elham Sabri, Mark Canney, Gregory L. Hundemer, Pierre-Antoine Brown, Manish M. Sood and Swapnil Hiremath
    Citation: Annals of Intensive Care 2021 11:174
  9. Authors: Surat Tongyoo, Porntipa Tantibundit, Kiattichai Daorattanachai, Tanuwong Viarasilpa, Chairat Permpikul and Suthipol Udompanturak
    Citation: Annals of Intensive Care 2021 11:173

    The original article was published in Annals of Intensive Care 2021 11:172

    The Research to this article has been published in Annals of Intensive Care 2021 11:135

  10. Authors: Radhouane Toumi, Khaoula Meddeb and Mohamed Boussarsar
    Citation: Annals of Intensive Care 2021 11:172

    The original article was published in Annals of Intensive Care 2021 11:135

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2021 11:173

  11. Only a few studies have reported the association between age and mortality in COVID-19 patients who require invasive mechanical ventilation (IMV). We aimed to evaluate the effect of age on COVID-19-related mor...

    Authors: Chie Tanaka, Takashi Tagami, Fumihiko Nakayama, Saori Kudo, Akiko Takehara, Reo Fukuda, Junya Kaneko, Yoshito Ishiki, Shin Sato, Ami Shibata, Masamune Kuno, Kyoko Unemoto, Masayuki Hojo, Tetsuya Mizoue, Yusuke Asai, Setsuko Suzuki…
    Citation: Annals of Intensive Care 2021 11:171
  12. Predicting outcomes of critically ill intensive care unit (ICU) patients with coronavirus-19 disease (COVID-19) is a major challenge to avoid futile, and prolonged ICU stays.

    Authors: Matthieu Schmidt, Bertrand Guidet, Alexandre Demoule, Maharajah Ponnaiah, Muriel Fartoukh, Louis Puybasset, Alain Combes and David Hajage
    Citation: Annals of Intensive Care 2021 11:170
  13. The coronavirus disease 2019 (COVID-19) pandemic has significantly influenced epidemiology, yet its impact on out-of-hospital cardiac arrest (OHCA) remains unclear. We aimed to evaluate the impact of the pande...

    Authors: Seth En Teoh, Yoshio Masuda, Darren Jun Hao Tan, Nan Liu, Laurie J. Morrison, Marcus Eng Hock Ong, Audrey L. Blewer and Andrew Fu Wah Ho
    Citation: Annals of Intensive Care 2021 11:169
  14. Atrial fibrillation (AF) is the most documented arrhythmia in COVID-19 pneumonia. Left atrial (LA) strain (LAS) analysis, a marker of LA contractility, have been associated with the development of AF in severa...

    Authors: Christophe Beyls, Alexis Hermida, Yohann Bohbot, Nicolas Martin, Christophe Viart, Solenne Boisgard, Camille Daumin, Pierre Huette, Hervé Dupont, Osama Abou-Arab and Yazine Mahjoub
    Citation: Annals of Intensive Care 2021 11:168
  15. Dynamic pulmonary hyperinflation may develop in patients with chronic obstructive pulmonary disease (COPD) due to dynamic airway collapse and/or increased airway resistance, increasing the risk of volutrauma a...

    Authors: L. H. Roesthuis, J. G. van der Hoeven, C. Guérin, J. Doorduin and L. M. A. Heunks
    Citation: Annals of Intensive Care 2021 11:167
  16. Among the long-term consequences of sepsis (also termed “post-sepsis syndrome”) the increased risk of unexplained cardiovascular complications, such as myocardial infarction, acute heart failure or stroke, is ...

    Authors: Hamid Merdji, Valérie Schini-Kerth, Ferhat Meziani and Florence Toti
    Citation: Annals of Intensive Care 2021 11:166
  17. Critical care randomized controlled trials (RCTs) are often published in high-impact journals, whether general journals [the New England Journal of Medicine (NEJM), The Lancet, the Journal of the American Medi...

    Authors: Joris Pensier, Audrey De Jong, Gerald Chanques, Emmanuel Futier, Elie Azoulay, Nicolas Molinari and Samir Jaber
    Citation: Annals of Intensive Care 2021 11:165
  18. Optimal flow settings during high-flow nasal cannula (HFNC) therapy are unknown. We investigated the optimal flow settings during HFNC therapy based on breathing pattern and tidal inspiratory flows in patients...

    Authors: Jie Li, J. Brady Scott, James B. Fink, Brooke Reed, Oriol Roca and Rajiv Dhand
    Citation: Annals of Intensive Care 2021 11:164
  19. Little is known about the effectiveness of surface cooling (SC) and endovascular cooling (EC) on the outcome of out-of-hospital cardiac arrest (OHCA) patients receiving target temperature management (TTM) acco...

    Authors: Makoto Watanabe, Tasuku Matsuyama, Hikaru Oe, Makoto Sasaki, Yuki Nakamura, Yuki Miyamoto, Nobunaga Okada, Tetsuhisa Kitamura and Bon Ohta
    Citation: Annals of Intensive Care 2021 11:163
  20. The death rate in intensive care units (ICUs) can reach 20%. More than half occurs after a decision of care withholding/withdrawal. We aimed at describing and evaluating the experience of ICU physicians and nu...

    Authors:
    Citation: Annals of Intensive Care 2021 11:162

    The Correction to this article has been published in Annals of Intensive Care 2021 11:186

  21. The role of intravenous immunoglobulins (IVIG) during sepsis is controversial, as different trials on IVIG have observed inconsistent survival benefits. We aimed to elucidate the possible association and clini...

    Authors: Laura Alagna, Jennifer M. T. A. Meessen, Giacomo Bellani, Daniela Albiero, Pietro Caironi, Irene Principale, Luigi Vivona, Giacomo Grasselli, Francesca Motta, Nicolò M. Agnelli, Vieri Parrini, Stefano Romagnoli, Roberto Keim, Francesca Di Marzo Capozzi, Fabio S. Taccone, Walter Taccone…
    Citation: Annals of Intensive Care 2021 11:161
  22. Ventilator-associated pneumonia (VAP) caused by Stenotrophomonas maltophilia is poorly described in the literature. However, it has been shown to be associated with increased morbidity and mortality. Probabilisti...

    Authors: Bérénice Puech, Clémence Canivet, Laura Teysseyre, Guillaume Miltgen, Thomas Aujoulat, Margot Caron, Chloé Combe, Julien Jabot, Olivier Martinet, Jerome Allyn, Cyril Ferdynus and Nicolas Allou
    Citation: Annals of Intensive Care 2021 11:160
  23. Some unanswered questions persist regarding the effectiveness of corticosteroids for severe coronavirus disease 2019 (COVID-19) patients. We aimed to assess the clinical effect of corticosteroids on intensive ...

    Authors: Gerard Moreno, Raquel Carbonell, Ignacio Martin-Loeches, Jordi Solé-Violán, Eudald Correig i Fraga, Josep Gómez, Manuel Ruiz-Botella, Sandra Trefler, María Bodí, Josefa Murcia Paya, Emili Díaz, Pablo Vidal-Cortes, Elisabeth Papiol, Antonio Albaya Moreno, Susana Sancho Chinesta, Lorenzo Socias Crespi…
    Citation: Annals of Intensive Care 2021 11:159
  24. Acute respiratory failure (ARF) in patients admitted to the intensive care unit (ICU) with known or de novo small-vessel vasculitis (Svv) may be secondary to the underlying immune disease or to other causes. E...

    Authors: Aude Gibelin, Guillaume Dumas, Sandrine Valade, Marc Pineton de Chambrun, François Bagate, Mathilde Neuville, Francis Schneider, Loredana Baboi, Matthieu Groh, Jean-Herlé Raphalen, Jean-Daniel Chiche, Nicolas De Prost, Charles-Edouard Luyt, Claude Guérin, Eric Maury, Etienne de Montmollin…
    Citation: Annals of Intensive Care 2021 11:158
  25. Since March 2020, health care systems were importantly affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak, with some patients presenting severe acute respiratory distress syndrom...

    Authors: Florence Daviet, Philippe Guilloux, Sami Hraiech, David Tonon, Lionel Velly, Jeremy Bourenne, Alizée Porto, Inès Gragueb-Chatti, Mickael Bobot, Karine Baumstarck, Laurent Papazian, Frédéric Collart, Jean-Marie Forel and Christophe Guervilly
    Citation: Annals of Intensive Care 2021 11:157
  26. Few data are available about outcomes of patients screened for, but not enrolled in, randomised clinical trials.

    Authors: J. B. Lascarrou, Gregoire Muller, Jean-Pierre Quenot, Nicolas Massart, Mickael Landais, Pierre Asfar, Jean-Pierre Frat, Jean-Charles Chakarian, Michel Sirodot, Bruno Francois, Guillaume Grillet, Sylvie Vimeux, Arnaud Delahaye, Stéphane Legriel, Didier Thevenin, Jean Reignier…
    Citation: Annals of Intensive Care 2021 11:156
  27. Initial reports have described the poor outcome of unexpected cardiac arrest (CA) in intensive care unit (ICU) among COVID-19 patients in China and the USA. However, there are scarce data on characteristics an...

    Authors: Jonathan Chelly, Gaetan Plantefève, Toufik Kamel, Cédric Bruel, Saad Nseir, Christopher Lai, Giulia Cirillo, Elena Skripkina, Sébastien Ehrminger, Fernando-Daniel Berdaguer-Ferrari, Julien Le Marec, Marine Paul, Aurélie Autret and Nicolas Deye
    Citation: Annals of Intensive Care 2021 11:155
  28. Baseline characteristics and disease severity of patients with septic shock according to the new Sepsis-3 definition may differ from patients that only comply with the Sepsis-2 definition. We conducted a retro...

    Authors: Joris Vermassen, Johan Decruyenaere, Liesbet De Bus, Pieter Depuydt and Kirsten Colpaert
    Citation: Annals of Intensive Care 2021 11:154
  29. The potential relationship between intravascular catheter infections with their insertion during weekend or night-time (i.e., off-hours or not regular business hours) remains an open issue. Our primary aim was to...

    Authors: Niccolò Buetti, Stéphane Ruckly, Jean-Christophe Lucet, Arthur Mageau, Claire Dupuis, Bertrand Souweine, Olivier Mimoz and Jean-François Timsit
    Citation: Annals of Intensive Care 2021 11:153
  30. COVID-19 is characterized by dysregulated immune response, respiratory failure and a relevant mortality rate among hospitalized patients. Interleukin-6 (IL-6) is involved in COVID-19-associated cytokine storm,...

    Authors: Alessandro Belletti, Corrado Campochiaro, Marilena Marmiere, Valery Likhvantsev, Andrey Yavorovskiy, Lorenzo Dagna, Giovanni Landoni, Alberto Zangrillo and Ludhmila Abrahão Hajjar
    Citation: Annals of Intensive Care 2021 11:152
  31. The first wave of the COVID-19 pandemic confronted healthcare systems around the world with unprecedented organizational challenges, particularly regarding the availability of intensive care unit (ICU) beds. O...

    Authors: Marc-Antoine Sanchez, Albert Vuagnat, Olivier Grimaud, Emmanuelle Leray, Jean-Marc Philippe, François-Xavier Lescure, Mathieu Boutonnet, Hélène Coignard, Agnès Ricard Hibon, Stephane Sanchez and Julien Pottecher
    Citation: Annals of Intensive Care 2021 11:151
  32. Prolonged need for mechanical ventilation greatly impacts life expectancy of patients after spinal cord injury (SCI). Weaning outcomes have never been systematically assessed. In this systematic review and met...

    Authors: Annia F. Schreiber, Jacopo Garlasco, Fernando Vieira, Yie Hui Lau, Dekel Stavi, David Lightfoot, Andrea Rigamonti, Karen Burns, Jan O. Friedrich, Jeffrey M. Singh and Laurent J. Brochard
    Citation: Annals of Intensive Care 2021 11:149
  33. The presence of bacteraemia in pneumococcal pneumonia in critically ill patients does not appear to be a strong independent prognostic factor in the existing literature. However, there may be a specific patter...

    Authors: Hugo Bellut, Raphael Porcher, Emmanuelle Varon, Pierre Asfar, Yves Le Tulzo, Bruno Megarbane, Armelle Mathonnet, Anthony Dugard, Anne Veinstein, Kader Ouchenir, Shidasp Siami, Jean Reignier, Arnaud Galbois, Joël Cousson, Sébastien Preau, Olivier Baldesi…
    Citation: Annals of Intensive Care 2021 11:148
  34. Ineffective triggering is frequent during pressure support ventilation (PSV) and may persist despite ventilator adjustment, leading to refractory asynchrony. We aimed to assess the effect of proportional assis...

    Authors: Anne-Fleur Haudebourg, Tommaso Maraffi, Samuel Tuffet, François Perier, Nicolas de Prost, Keyvan Razazi, Armand Mekontso Dessap and Guillaume Carteaux
    Citation: Annals of Intensive Care 2021 11:147
  35. Echocardiographic parameters have been poorly investigated for estimating cardiovascular risk in patients with sepsis and new-onset atrial fibrillation. We aim to assess the prevalence of transesophageal echoc...

    Authors: Vincent Labbé, Stephane Ederhy, Nathanael Lapidus, Jérémie Joffre, Keyvan Razazi, Laurent Laine, Oumar Sy, Sebastian Voicu, Frank Chemouni, Nadia Aissaoui, Roland Smonig, Denis Doyen, Fabrice Carrat, Guillaume Voiriot, Armand Mekontso-Dessap, Ariel Cohen…
    Citation: Annals of Intensive Care 2021 11:146
  36. In comatose patients receiving oro-tracheal intubation for mechanical ventilation (MV), the risk of aspiration is increased. Aspiration can lead to chemical pneumonitis (inflammatory reaction to the gastric co...

    Authors: Guylaine Labro, François Aptel, Marc Puyraveau, Jonathan Paillot, Sébastien Pili Floury, Hamid Merdji, Julie Helms, Gaël Piton, Fiona Ecarnot, Khaldoun Kuteifan, Jean Pierre Quenot and Gilles Capellier
    Citation: Annals of Intensive Care 2021 11:145
  37. ICU-acquired weakness (ICUAW) has been shown to be associated with prolonged duration of mechanical ventilation and extubation failure. It is usually assessed through Medical Research Council (MRC) score, a ti...

    Authors: Guillaume Cottereau, Jonathan Messika, Bruno Megarbane, Laurent Guérin, Daniel da Silva, Caroline Bornstain, Matilde Santos, Jean-Damien Ricard and Benjamin Sztrymf
    Citation: Annals of Intensive Care 2021 11:144
  38. Information is lacking regarding long-term survival and predictive factors for mortality in patients with acute hypoxemic respiratory failure due to coronavirus disease 2019 (COVID-19) and undergoing invasive ...

    Authors: Oscar Peñuelas, Laura del Campo-Albendea, Amanda Lesmes González de Aledo, José Manuel Añón, Carmen Rodríguez-Solís, Jordi Mancebo, Paula Vera, Daniel Ballesteros, Jorge Jiménez, Emilio Maseda, Juan Carlos Figueira, Nieves Franco, Ángela Algaba, Juan Pablo Avilés, Ricardo Díaz, Beatriz Abad…
    Citation: Annals of Intensive Care 2021 11:143
  39. A delay in admission to the intensive care unit (ICU) of patients with community-acquired pneumonia (CAP) has been associated with an increased mortality. Decisions regarding interventions and eligibility for ...

    Authors: Liza Pereverzeva, Fabrice Uhel, Hessel Peters Sengers, Olaf L. Cremer, Marcus J. Schultz, Marc M. J. Bonten, Brendon P. Scicluna and Tom van der Poll
    Citation: Annals of Intensive Care 2021 11:142
  40. Polymyxin B hemoperfusion (PMX) aims to treat septic shock by removing endotoxin from the patient’s blood. However, the relationship between the severity of the patient's organ damage and the survival benefit ...

    Authors: Kenji Fujimori, Kunio Tarasawa and Kiyohide Fushimi
    Citation: Annals of Intensive Care 2021 11:141
  41. Myoglobin and creatine kinase (CK) are both established markers of muscle injury but their hospital admission values have never been compared to predict post-traumatic acute kidney injury (AKI).

    Authors: Virginie Tarazona, Samy Figueiredo, Sophie Hamada, Jonas Pochard, Ryan W. Haines, John R. Prowle, Jacques Duranteau, Bernard Vigué and Anatole Harrois
    Citation: Annals of Intensive Care 2021 11:140
  42. The optimal mean arterial pressure (MAP) in cases of septic shock is still a matter of debate in patients with prior hypertension. An MAP between 75 and 85 mmHg can improve glomerular filtration rate (GFR) but...

    Authors: Antoine Dewitte, Aurore Labat, Pierre-Antoine Duvignaud, Gauthier Bouche, Olivier Joannes-Boyau, Jean Ripoche, Gilles Hilbert, Didier Gruson, Sébastien Rubin, Alexandre Ouattara, Alexandre Boyer and Christian Combe
    Citation: Annals of Intensive Care 2021 11:139
  43. Invasive pulmonary aspergillosis (IPA) has always been a challenging diagnosis and risk factors an important guide to investigate specific population, especially in Intensive Care Unit. Traditionally recognize...

    Authors: G. Montrucchio, T. Lupia, D. Lombardo, G. Stroffolini, S. Corcione, F. G. De Rosa and L. Brazzi
    Citation: Annals of Intensive Care 2021 11:136
  44. High-flow nasal oxygen cannula (HFNC) and noninvasive mechanical ventilation (NIV) can prevent reintubation in critically ill patients. However, their efficacy in post-extubated sepsis patients remains unclear...

    Authors: Surat Tongyoo, Porntipa Tantibundit, Kiattichai Daorattanachai, Tanuwong Viarasilpa, Chairat Permpikul and Suthipol Udompanturak
    Citation: Annals of Intensive Care 2021 11:135

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2021 11:172

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2021 11:173

  45. The aim of this study was to validate whether regional ventilation and perfusion data measured by electrical impedance tomography (EIT) with saline bolus could discriminate three broad acute respiratory failur...

    Authors: Huaiwu He, Yi Chi, Yun Long, Siyi Yuan, Rui Zhang, Yingying Yang, Inéz Frerichs, Knut Möller, Feng Fu and Zhanqi Zhao
    Citation: Annals of Intensive Care 2021 11:134
  46. The end-expiratory occlusion (EEXPO) test detects preload responsiveness, but it is 15 s long and induces small changes in cardiac index (CI). It is doubtful whether the Starling bioreactance device, which ave...

    Authors: Francesco Gavelli, Alexandra Beurton, Jean-Louis Teboul, Nello De Vita, Danila Azzolina, Rui Shi, Arthur Pavot and Xavier Monnet
    Citation: Annals of Intensive Care 2021 11:133
  47. Cardiogenic pulmonary oedema (CPE) may contribute to ventilator-associated lung injury (VALI) in patients with cardiogenic shock. The appropriate ventilatory strategy remains unclear. We aimed to evaluate the ...

    Authors: Laura Amado-Rodríguez, Cecilia Del Busto, Inés López-Alonso, Diego Parra, Juan Mayordomo-Colunga, Miguel Arias-Guillén, Rodrigo Albillos-Almaraz, Paula Martín-Vicente, Cecilia López-Martínez, Covadonga Huidobro, Luigi Camporota, Arthur S. Slutsky and Guillermo M. Albaiceta
    Citation: Annals of Intensive Care 2021 11:132

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