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  1. Intravenous fluid administration should be considered as any other pharmacological prescription. There are three main indications: resuscitation, replacement, and maintenance. Moreover, the impact of fluid adm...

    Authors: Manu L. N. G. Malbrain, Thomas Langer, Djillali Annane, Luciano Gattinoni, Paul Elbers, Robert G. Hahn, Inneke De laet, Andrea Minini, Adrian Wong, Can Ince, David Muckart, Monty Mythen, Pietro Caironi and Niels Van Regenmortel

    Citation: Annals of Intensive Care 2020 10:64

    Content type: Review

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  2. COVID-19 is an emerging disease of public health concern. While there is no specific recommended treatment for COVID-19, nitric oxide has the potential to be of therapeutic value for managing acute respiratory...

    Authors: Jun Kobayashi and Isamu Murata

    Citation: Annals of Intensive Care 2020 10:61

    Content type: Letter to the Editor

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  3. Bacterial infections are frequent triggers for diabetic ketoacidosis. In this context, delayed antibiotic treatment is associated with increased morbidity and mortality. Unnecessary administration of antimicro...

    Authors: Florian Blanchard, Judith Charbit, Guillaume Van der Meersch, Benjamin Popoff, Adrien Picod, Regis Cohen, Frank Chemouni, Stephane Gaudry, Helene Bihan and Yves Cohen

    Citation: Annals of Intensive Care 2020 10:58

    Content type: Research

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    The Correction to this article has been published in Annals of Intensive Care 2020 10:72

  4. Although recently published randomised controlled trials did not confirm significant positive effect of ART-123 or polymyxin B‑immobilised haemoperfusion (PMX-HP) on survival outcome, previous studies using a ...

    Authors: Katsunori Mochizuki, Kotaro Mori, Hiroshi Kamijo, Michitaro Ichikawa, Kenichi Nitta and Hiroshi Imamura

    Citation: Annals of Intensive Care 2020 10:57

    Content type: Research

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  5. The number of intensive care patients aged ≥ 80 years (Very old Intensive Care Patients; VIPs) is growing. VIPs have high mortality and morbidity and the benefits of ICU admission are frequently questioned. Se...

    Authors: Mercedes Ibarz, Ariane Boumendil, Lenneke E. M. Haas, Marian Irazabal, Hans Flaatten, Dylan W. de Lange, Alessandro Morandi, Finn H. Andersen, Guido Bertolini, Maurizio Cecconi, Steffen Christensen, Loredana Faraldi, Jesper Fjølner, Christian Jung, Brian Marsh, Rui Moreno…

    Citation: Annals of Intensive Care 2020 10:56

    Content type: Research

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  6. A large proportion of patients with a SARS-Cov-2-associated respiratory failure develop an acute respiratory distress syndrome (ARDS). It has been recently suggested that SARS-Cov-2-associated ARDS may differ ...

    Authors: François M. Beloncle, Bertrand Pavlovsky, Christophe Desprez, Nicolas Fage, Pierre-Yves Olivier, Pierre Asfar, Jean-Christophe Richard and Alain Mercat

    Citation: Annals of Intensive Care 2020 10:55

    Content type: Research

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  7. Weaning from mechanical ventilation (MV) is a cardiovascular stress test. Monitoring the regional oxygenation status has shown promising results in predicting the tolerance to spontaneously breathe in the proc...

    Authors: Jaume Mesquida, Guillem Gruartmoner, Cristina Espinal, Jordi Masip, Caroline Sabatier, Ana Villagrá, Hernando Gómez, Michael Pinsky, Francisco Baigorri and Antonio Artigas

    Citation: Annals of Intensive Care 2020 10:54

    Content type: Research

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  8. Most prognostic studies in acute stroke patients requiring invasive mechanical ventilation are outdated and have limitations such as single-center retrospective designs. We aimed to study the association of IC...

    Authors: Etienne de Montmollin, Nicolas Terzi, Claire Dupuis, Maité Garrouste-Orgeas, Daniel da Silva, Michaël Darmon, Virginie Laurent, Guillaume Thiéry, Johana Oziel, Guillaume Marcotte, Marc Gainnier, Shidasp Siami, Benjamin Sztrymf, Christophe Adrie, Jean Reignier, Stephane Ruckly…

    Citation: Annals of Intensive Care 2020 10:53

    Content type: Research

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  9. Acute respiratory distress syndrome (ARDS) is a life-threatening condition that often requires prolonged mechanical ventilation. Tracheostomy is a common procedure with some risks, on the other hand with poten...

    Authors: Sebastian Blecha, Magdalena Brandl, Florian Zeman, Frank Dodoo-Schittko, Susanne Brandstetter, Christian Karagiannidis, Thomas Bein and Christian Apfelbacher

    Citation: Annals of Intensive Care 2020 10:52

    Content type: Research

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  10. Neutrophil gelatinase-associated lipocalin (NGAL) is released from kidney tubular cells under stress as well as from neutrophils during inflammation. It has been suggested as a biomarker for acute kidney injur...

    Authors: Sanna Törnblom, Sara Nisula, Liisa Petäjä, Suvi T. Vaara, Mikko Haapio, Eero Pesonen and Ville Pettilä

    Citation: Annals of Intensive Care 2020 10:51

    Content type: Research

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  11. In this survey endorsed by the European Society of Intensive Care Medicine (ESICM), we aimed to describe the practice patterns of intensivists worldwide, regarding their diagnosis and management of respiratory...

    Authors: Quentin Philippot, Vincent Labbé, Jérémie Pichon, Michel Djibré, Muriel Fartoukh and Guillaume Voiriot

    Citation: Annals of Intensive Care 2020 10:50

    Content type: Letter to the Editor

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  12. The echocardiography working group of the European Society of Intensive Care Medicine recognized the need to provide structured guidance for future CCE research methodology and reporting based on a systematic ...

    Authors: S. Huang, F. Sanfilippo, A. Herpain, M. Balik, M. Chew, F. Clau-Terré, C. Corredor, D. De Backer, N. Fletcher, G. Geri, A. Mekontso-Dessap, A. McLean, A. Morelli, S. Orde, T. Petrinic, M. Slama…

    Citation: Annals of Intensive Care 2020 10:49

    Content type: Review

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  13. Infection and sepsis are a main cause of acute-on-chronic liver failure (ACLF). Adequate dosing of antimicrobial therapy is of central importance to improve outcome. Liver failure may alter antibiotic drug con...

    Authors: Jörn Grensemann, David Busse, Christina König, Kevin Roedl, Walter Jäger, Dominik Jarczak, Stefanie Iwersen-Bergmann, Carolin Manthey, Stefan Kluge, Charlotte Kloft and Valentin Fuhrmann

    Citation: Annals of Intensive Care 2020 10:48

    Content type: Research

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  14. Despite improvements in intermittent hemodialysis management, intradialytic hemodynamic instability (IHI) remains a common issue that could account for increased mortality and delayed renal recovery. However, ...

    Authors: Naïke Bigé, Jean-Rémi Lavillegrand, Julien Dang, Philippe Attias, Stéphanie Deryckere, Jérémie Joffre, Vincent Dubée, Gabriel Preda, Guillaume Dumas, Geoffroy Hariri, Claire Pichereau, Jean-Luc Baudel, Bertrand Guidet, Eric Maury, Pierre-Yves Boelle and Hafid Ait-Oufella

    Citation: Annals of Intensive Care 2020 10:47

    Content type: Research

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  15. Biomarkers can play a critical role by facilitating diagnosis and stratification of disease, as well as assessment or prediction of disease severity. Urinary tissue inhibitor of metalloproteinase-2 and insulin...

    Authors: Ilaria Godi, Silvia De Rosa, Francesca Martino, Simona Bazzano, Marina Martin, Elisa Boni, Maria Rosa Carta, Claudia Tamayo Diaz, Gaia Mari, Anna Lorenzin, Massimo de Cal, Valentina Corradi, Carlotta Caprara, Davide Giavarina and Claudio Ronco

    Citation: Annals of Intensive Care 2020 10:46

    Content type: Research

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  16. Since the 2019 novel coronavirus disease (COVID-19) outbreak originated from Wuhan, Hubei Province, China, at the end of 2019, it has become a clinical threat to the general population worldwide. Among people ...

    Authors: Lei Li, Ranran Li, Zhixiong Wu, Xianghong Yang, Mingyan Zhao, Jiao Liu and Dechang Chen

    Citation: Annals of Intensive Care 2020 10:45

    Content type: Review

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  17. To describe acute kidney injury (AKI) natural history and to identify predictors of major adverse kidney events (MAKE) within 1 year in patients supported by veno-arterial extracorporeal membrane oxygenation (...

    Authors: Camille Vinclair, Etienne De Montmollin, Romain Sonneville, Jean Reuter, Jordane Lebut, Radj Cally, Bruno Mourvillier, Mathilde Neuville, Stéphane Ruckly, Jean-François Timsit and Lila Bouadma

    Citation: Annals of Intensive Care 2020 10:44

    Content type: Research

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  18. Acute kidney injury (AKI) is a common problem in critically ill patients and associated with high rates of morbidity and mortality. Recently, Major Adverse Kidney Events (MAKE) were introduced as important kid...

    Authors: Theerapon Sukmark, Nuttha Lumlertgul, Kearkiat Praditpornsilpa, Kriang Tungsanga, Somchai Eiam-Ong and Nattachai Srisawat

    Citation: Annals of Intensive Care 2020 10:42

    Content type: Research

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  19. Loss of vascular tone is a key pathophysiological feature of septic shock. Combination of gradual diastolic hypotension and tachycardia could reflect more serious vasodilatory conditions. We sought to evaluate...

    Authors: Gustavo A. Ospina-Tascón, Jean-Louis Teboul, Glenn Hernandez, Ingrid Alvarez, Alvaro I. Sánchez-Ortiz, Luis E. Calderón-Tapia, Ramiro Manzano-Nunez, Edgardo Quiñones, Humberto J. Madriñan-Navia, Juan E. Ruiz, José L. Aldana and Jan Bakker

    Citation: Annals of Intensive Care 2020 10:41

    Content type: Research

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  20. Resuscitation of septic patients regarding goals, monitoring aspects and therapy is highly variable. Our aim was to characterize cardiovascular and fluid management of sepsis in Argentina, a low and middle-inc...

    Authors: Arnaldo Dubin, Cecilia Loudet, Vanina S. Kanoore Edul, Javier Osatnik, Fernando Ríos, Daniela Vásquez, Mario Pozo, Bernardo Lattanzio, Fernando Pálizas, Francisco Klein, Damián Piezny, Paolo N. Rubatto Birri, Graciela Tuhay, Analía García, Analía Santamaría, Graciela Zakalik…

    Citation: Annals of Intensive Care 2020 10:40

    Content type: Research

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  21. Pendelluft, the movement of gas within different lung regions, is present in animal models of assisted mechanical ventilation and associated with lung overstretching. Due to rebreathing of CO2 as compared to fres...

    Authors: Andrea Coppadoro, Alice Grassi, Cecilia Giovannoni, Francesca Rabboni, Nilde Eronia, Alfio Bronco, Giuseppe Foti, Roberto Fumagalli and Giacomo Bellani

    Citation: Annals of Intensive Care 2020 10:39

    Content type: Research

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  22. The aim of the study was to detect differences in the conjunctival microcirculation between septic patients and healthy subjects and to evaluate the course of conjunctival and retinal microvasculature in survi...

    Authors: Jurate Simkiene, Zivile Pranskuniene, Astra Vitkauskiene, Vidas Pilvinis, E. Christiaan Boerma and Andrius Pranskunas

    Citation: Annals of Intensive Care 2020 10:38

    Content type: Research

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  23. The outbreak of a novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) is currently ongoing in China. Most of the critically ill patients received high-flow nasal cannula (HFNC) oxygen therapy. However, the...

    Authors: Ke Wang, Wei Zhao, Ji Li, Weiwei Shu and Jun Duan

    Citation: Annals of Intensive Care 2020 10:37

    Content type: Research

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  24. Lactate is a robust prognostic marker for the outcome of critically ill patients. Several small studies reported that metformin users have higher lactate levels at ICU admission without a concomitant increase ...

    Authors: Rene A. Posma, Trine Frøslev, Bente Jespersen, Iwan C. C. van der Horst, Daan J. Touw, Reimar W. Thomsen, Maarten W. Nijsten and Christian F. Christiansen

    Citation: Annals of Intensive Care 2020 10:36

    Content type: Research

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    The Letter to the Editor to this article has been published in Annals of Intensive Care 2020 10:148

  25. Ventilation/perfusion inequalities impair gas exchange in acute respiratory distress syndrome (ARDS). Although increased dead-space ventilation (VD/VT) has been described in ARDS, its mechanism is not clearly und...

    Authors: Gustavo A. Ospina-Tascón, Diego F. Bautista, Humberto J. Madriñán, Juan D. Valencia, William F. Bermúdez, Edgardo Quiñones, Luis Eduardo Calderón-Tapia, Glenn Hernandez, Alejandro Bruhn and Daniel De Backer

    Citation: Annals of Intensive Care 2020 10:35

    Content type: Research

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  26. Evidence supporting corticosteroids adjunctive treatment (CAT) for Pneumocystis jirovecii pneumonia (PCP) in non-HIV patients is highly controversial. We aimed to systematically review the literature and perform ...

    Authors: Lin Ding, Huixue Huang, Heyan Wang and Hangyong He

    Citation: Annals of Intensive Care 2020 10:34

    Content type: Research

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  27. Severe acute kidney injury (AKI), especially when caused or accompanied by sepsis, is associated with prolonged hospitalization, progression to chronic kidney disease (CKD), financial burden, and high mortalit...

    Authors: Ayman Karkar and Claudio Ronco

    Citation: Annals of Intensive Care 2020 10:32

    Content type: Review

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  28. High-frequency oscillatory ventilation (HFOV) may theoretically provide lung protective ventilation. The negative clinical results may be due to inadequate mean airway pressure (mPaw) settings in HFOV. Our obj...

    Authors: Songqiao Liu, Zhanqi Zhao, Li Tan, Lihui Wang, Knut Möller, Inéz Frerichs, Tao Yu, Yingzi Huang, Chun Pan, Yi Yang and Haibo Qiu

    Citation: Annals of Intensive Care 2020 10:31

    Content type: Research

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  29. The optimal timing of renal replacement therapy (RRT) initiation is debatable. Many articles in this field enrolled trials not based on acute kidney injury. The safety of the watchful waiting strategy has not ...

    Authors: Jia-Jin Chen, Cheng-Chia Lee, George Kuo, Pei-Chun Fan, Chan-Yu Lin, Su-Wei Chang, Ya-Chung Tian, Yung-Chang Chen and Chih-Hsiang Chang

    Citation: Annals of Intensive Care 2020 10:30

    Content type: Research

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  30. After publication of the original article [1], we were notified that family names have been exchanged with the first names for all authors. Below the name are tagged correctly:

    Authors: Jordane Lebut, Bruno Mourvillier, Nicolas Argy, Claire Dupuis, Camille Vinclair, Aguila Radjou, Etienne de Montmollin, Fabrice Sinnah, Juliette Patrier, Clément Le Bihan, Eric Magalahes, Roland Smonig, Eric Kendjo, Marc Thellier, Stéphane Ruckly, Lila Bouadma…

    Citation: Annals of Intensive Care 2020 10:29

    Content type: Correction

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    The original article was published in Annals of Intensive Care 2020 10:21

  31. It has been suggested that, by recruiting lung regions and enlarging the distribution volume of the cold indicator, increasing the positive end-expiratory pressure (PEEP) may lead to an artefactual overestimat...

    Authors: Francesco Gavelli, Jean-Louis Teboul, Danila Azzolina, Alexandra Beurton, Temistocle Taccheri, Imane Adda, Christopher Lai, Gian Carlo Avanzi and Xavier Monnet

    Citation: Annals of Intensive Care 2020 10:28

    Content type: Research

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  32. Rhabdomyolysis is a life-threatening disease that can lead to severe hyperkalemia, acute kidney injury (AKI) and hypovolemic shock. The predictive factors of AKI and acute to chronic kidney disease (CKD) trans...

    Authors: Nelly Candela, Stein Silva, Bernard Georges, Claire Cartery, Thomas Robert, Julie Moussi-Frances, Eric Rondeau, Jean-Michel Rebibou, Laurence Lavayssiere, Julie Belliere, Thierry Krummel, Céline Lebas, Olivier Cointault, Marion Sallee and Stanislas Faguer

    Citation: Annals of Intensive Care 2020 10:27

    Content type: Research

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  33. Corticosteroid treatment has been widely used in the treatment of septic shock, influenza, and ARDS, although some previous studies discourage its use in severe influenza patients. This multicenter retrospecti...

    Authors: Ming-Ju Tsai, Kuang-Yao Yang, Ming-Cheng Chan, Kuo-Chin Kao, Hao-Chien Wang, Wann-Cherng Perng, Chieh-Liang Wu, Shinn-Jye Liang, Wen-Feng Fang, Jong-Rung Tsai, Wei-An Chang, Ying-Chun Chien, Wei-Chih Chen, Han-Chung Hu, Chiung-Yu Lin, Wen-Cheng Chao…

    Citation: Annals of Intensive Care 2020 10:26

    Content type: Research

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  34. Right ventricular (RV) function evaluation by echocardiography is key in the management of ICU patients with acute respiratory distress syndrome (ARDS), however, it remains challenging. Quantification of RV de...

    Authors: Jérémie Lemarié, Charles-Henri Maigrat, Antoine Kimmoun, Nathalie Dumont, Pierre-Edouard Bollaert, Christine Selton-Suty, Sébastien Gibot and Olivier Huttin

    Citation: Annals of Intensive Care 2020 10:24

    Content type: Research

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  35. The primary aim of the present contribution is to find a literature-based agreement on dose adjustments of vitamin C in critically ill patients undergoing renal replacement therapy (RRT).

    Authors: Patrick M. Honore, Herbert D. Spapen, Paul Marik, Willem Boer and Heleen Oudemans-van Straaten

    Citation: Annals of Intensive Care 2020 10:23

    Content type: Review

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  36. In France, the incidence of severe imported malaria cases increased since early 2000. Artesunate was available (temporarily use authorization) since mid-2011 in France and commonly used for severe malaria sinc...

    Authors: Jordane Lebut, Bruno Mourvillier, Nicolas Argy, Claire Dupuis, Camille Vinclair, Aguila Radjou, Etienne de Montmollin, Fabrice Sinnah, Juliette Patrier, Clément Le Bihan, Eric Magalahes, Roland Smonig, Eric Kendjo, Marc Thellier, Stéphane Ruckly, Lila Bouadma…

    Citation: Annals of Intensive Care 2020 10:21

    Content type: Research

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    The Correction to this article has been published in Annals of Intensive Care 2020 10:29

  37. The influence of socioeconomic status on patient outcomes is unclear. We assessed the impact of socioeconomic deprivation on severity of illness at intensive care unit (ICU) admission, and on the risk of death...

    Authors: Jean-Pierre Quenot, Julie Helms, Guylaine Labro, Auguste Dargent, Nicolas Meunier-Beillard, Elea Ksiazek, Pierre-Edouard Bollaert, Guillaume Louis, Audrey Large, Pascal Andreu, Christophe Bein, Jean-Philippe Rigaud, Pierre Perez, Raphaël Clere-Jehl, Hamid Merdji, Hervé Devilliers…

    Citation: Annals of Intensive Care 2020 10:20

    Content type: Research

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  38. Protective mechanical ventilation is recommended for patients with acute respiratory distress syndrome (ARDS), but it usually requires controlled ventilation and sedation. Using neurally adjusted ventilatory a...

    Authors: Fabia Diniz-Silva, Henrique T. Moriya, Adriano M. Alencar, Marcelo B. P. Amato, Carlos R. R. Carvalho and Juliana C. Ferreira

    Citation: Annals of Intensive Care 2020 10:18

    Content type: Research

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  39. High glycemic variability (GV) is common in critically ill patients; however, the prevalence and mortality association with early GV in patients with sepsis remains unclear.

    Authors: Wen-Cheng Chao, Chien-Hua Tseng, Chieh-Liang Wu, Sou-Jen Shih, Chi-Yuan Yi and Ming-Cheng Chan

    Citation: Annals of Intensive Care 2020 10:17

    Content type: Research

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  40. The US Centers for Disease Control and Prevention (CDC) recently released simplified eSOFA organ dysfunction criteria of Adult Sepsis Event for sepsis surveillance in the US. Our study aimed to compare the pre...

    Authors: Run Dong, Hongcheng Tian, Jianfang Zhou, Li Weng, Xiaoyun Hu, Jinmin Peng, Chunyao Wang, Wei Jiang, Xueping Du, Xiuming Xi, Youzhong An, Meili Duan and Bin Du

    Citation: Annals of Intensive Care 2020 10:14

    Content type: Research

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  41. Protective ventilation is the cornerstone of treatment of patients with the acute respiratory distress syndrome (ARDS); however, no studies have yet established the best ventilatory strategy to adopt when pati...

    Authors: Alessandro Marchioni, Roberto Tonelli, Giulio Rossi, Paolo Spagnolo, Fabrizio Luppi, Stefania Cerri, Elisabetta Cocconcelli, Maria Rosaria Pellegrino, Riccardo Fantini, Luca Tabbì, Ivana Castaniere, Lorenzo Ball, Manu L. N. G. Malbrain, Paolo Pelosi and Enrico Clini

    Citation: Annals of Intensive Care 2020 10:13

    Content type: Review

    Published on:

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