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  1. Whether early fluid accumulation is a risk factor for adverse renal outcomes in septic intensive care unit (ICU) patients remains uncertain. We assessed the association between cumulative fluid balance and maj...

    Authors: Alessandro Mele, Emanuele Cerminara, Henrike Häbel, Borja Rodriguez-Galvez, Anders Oldner, David Nelson, Johannes Gårdh, Ragnar Thobaben, Sandra Jonmarker, Maria Cronhjort, Jacob Hollenberg and Johan Mårtensson
    Citation: Annals of Intensive Care 2022 12:62
  2. Excess exposure to norepinephrine can compromise microcirculation and organ function. We aimed to assess the association between norepinephrine exposure and acute kidney injury (AKI) and intensive care unit (I...

    Authors: Pierre Huette, Mouhamed Djahoum Moussa, Christophe Beyls, Pierre-Grégoire Guinot, Mathieu Guilbart, Patricia Besserve, Mehdi Bouhlal, Sarah Mounjid, Hervé Dupont, Yazine Mahjoub, Audrey Michaud and Osama Abou-Arab
    Citation: Annals of Intensive Care 2022 12:61
  3. Authors: Benoit Painvin, Stephan Ehrmann, Arnaud W. Thille and Jean-Marc Tadié
    Citation: Annals of Intensive Care 2022 12:60

    The original article was published in Annals of Intensive Care 2022 12:31

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:63

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:63

  4. In our recent survey, we aimed to collect information on perceived inequity as well as professional and personal fulfillment among women intensivists in France. For the 371 respondents out of the 732 persons w...

    Authors: Olfa Hamzaoui, Florence Boissier, Charlotte Salmon Gandonnière, Cécile Aubron, Laetitia Bodet-Contentin, Muriel Sarah Fartoukh, Mélanie Faure, Mercedes Jourdain, Julien Le Marec, Fabienne Tamion, Nicolas Terzi, Caroline Hauw-Berlemont and Nadia Aissaoui
    Citation: Annals of Intensive Care 2022 12:59
  5. Post‐intensive care syndrome (PICS) encompasses physical, cognition, and mental impairments persisting after intensive care unit (ICU) discharge. Ultimately it significantly impacts the long‐term prognosis, bo...

    Authors: Guillaume Voiriot, Mehdi Oualha, Alexandre Pierre, Charlotte Salmon-Gandonnière, Alexandre Gaudet, Youenn Jouan, Hatem Kallel, Peter Radermacher, Dominique Vodovar, Benjamine Sarton, Laure Stiel, Nicolas Bréchot, Sébastien Préau and Jérémie Joffre
    Citation: Annals of Intensive Care 2022 12:58
  6. The high transmission and fatality rates of coronavirus disease 2019 (COVID-19) strain intensive care resources and affect the treatment and prognosis of critically ill patients without COVID-19. Therefore, th...

    Authors: Sua Kim, Hangseok Choi, Jae Kyeom Sim, Won Jai Jung, Young Seok Lee and Je Hyeong Kim
    Citation: Annals of Intensive Care 2022 12:57
  7. Previous studies have found an increase in cardiac troponins (cTns) and echocardiographic abnormalities in patients with COVID-19 and reported their association with poor clinical outcomes. Whether acute injur...

    Authors: Saga Jansson, Patrik Johansson Blixt, Helen Didriksson, Carina Jonsson, Henrik Andersson, Cassandra Hedström, Jan Engvall, Meriam Åstrom Aneq and Michelle S. Chew
    Citation: Annals of Intensive Care 2022 12:56

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:82

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:83

  8. Hyperammonaemia is frequent in Intensive Care Unit patients. Some drugs have been described as associated with this condition, but there are no large-scale studies investigating this topic and most description...

    Authors: Alexander Balcerac, Kevin Bihan, Bénédicte Lebrun-Vignes, Dominique Thabut, Joe-Elie Salem and Nicolas Weiss
    Citation: Annals of Intensive Care 2022 12:55
  9. Pressure injuries (PIs), especially in the sacral region are frequent, costly, and increase morbidity and mortality of patients in an intensive care unit (ICU). These injuries can occur as a result of prolonge...

    Authors: Miriam Viviane Baron, Paulo Eugênio Silva, Janine Koepp, Janete de Souza Urbanetto, Andres Felipe Mantilla Santamaria, Michele Paula dos Santos, Marcus Vinicius de Mello Pinto, Cristine Brandenburg, Isabel Cristina Reinheimer, Sonia Carvalho, Mário Bernardes Wagner, Thomas Miliou, Carlos Eduardo Poli-de-Figueiredo and Bartira Ercília Pinheiro da Costa
    Citation: Annals of Intensive Care 2022 12:53
  10. Fluid overload is a risk factor for organ dysfunction and death in intensive care unit (ICU) patients, but no guidelines exist for its management. We systematically reviewed benefits and harms of a single loop...

    Authors: Sine Wichmann, Marija Barbateskovic, Ning Liang, Theis Skovsgaard Itenov, Rasmus Ehrenfried Berthelsen, Jane Lindschou, Anders Perner, Christian Gluud and Morten Heiberg Bestle
    Citation: Annals of Intensive Care 2022 12:52
  11. Some clinical and histological studies have reported that SARS-CoV-2 infection may damage the endothelium. However, the impact of this virus on endothelial function in vivo remains poorly characterized. In thi...

    Authors: Lisa Raia, Tomas Urbina, Paul Gabarre, Vincent Bonny, Geoffroy Hariri, Sebastien Ehrminger, Naïke Bigé, Jean-Luc Baudel, Bertrand Guidet, Eric Maury, Jeremie Joffre and Hafid Ait-Oufella
    Citation: Annals of Intensive Care 2022 12:51
  12. Dyspnea, a key symptom of acute respiratory failure, is not among the criteria for spontaneous breathing trial (SBT) failure. Here, we sought (1) to determine whether dyspnea is a reliable failure criterion fo...

    Authors: Côme Bureau, Martin Dres, Elise Morawiec, Julien Mayaux, Julie Delemazure, Thomas Similowski and Alexandre Demoule
    Citation: Annals of Intensive Care 2022 12:50
  13. Intensive care unit (ICU) patients often endure discomfort and distress brought about by their medical environment and the subjective experience of their stay. Distress, pain, and loss of control are important...

    Authors: Irma Bourgeon-Ghittori, Maryline Couette, Sylvie Marini, Rachida Ouedraogo, Aline Alves, Keyvan Razazi, Damien Carras, Ann-Cecile Pallud, Nancy Kentish-Barnes and Armand Mekontso Dessap
    Citation: Annals of Intensive Care 2022 12:49
  14. Organ shortage is a major public health issue, and patients who die after out-of-hospital cardiac arrest (OHCA) could be a valuable source of organs. Here, our objective was to identify factors associated with...

    Authors: M. Renaudier, Y. Binois, F. Dumas, L. Lamhaut, F. Beganton, D. Jost, J. Charpentier, O. Lesieur, E. Marijon, X. Jouven, A. Cariou and W. Bougouin
    Citation: Annals of Intensive Care 2022 12:48
  15. Septic shock remains a health care concern associated with significant morbidity and mortality. The Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock recommend early fluid resuscit...

    Authors: Mahmoud A. Ammar, Abdalla A. Ammar, Patrick M. Wieruszewski, Brittany D. Bissell, Micah T. Long, Lauren Albert, Ashish K. Khanna and Gretchen L. Sacha
    Citation: Annals of Intensive Care 2022 12:47
  16. Although the administration of fluid is the first treatment considered in almost all cases of circulatory failure, this therapeutic option poses two essential problems: the increase in cardiac output induced b...

    Authors: Xavier Monnet, Rui Shi and Jean-Louis Teboul
    Citation: Annals of Intensive Care 2022 12:46
  17. Hemadsorption of cytokines is used in critically ill patients with sepsis or septic shock. Concerns have been raised that the cytokine adsorber CytoSorb® unintentionally adsorbs vancomycin. This study aimed to qu...

    Authors: Christina Scharf, Ferdinand Weinelt, Ines Schroeder, Michael Paal, Michael Weigand, Michael Zoller, Michael Irlbeck, Charlotte Kloft, Josef Briegel and Uwe Liebchen
    Citation: Annals of Intensive Care 2022 12:44
  18. Hospital-acquired pneumonia (HAP) is the most common and severe complication in patients treated with venoarterial extracorporeal membrane oxygenation (VA ECMO) and its diagnosis remains challenging. Nothing i...

    Authors: Jean Pasqueron, Pauline Dureau, Gauthier Arcile, Baptiste Duceau, Geoffroy Hariri, Victoria Lepère, Guillaume Lebreton, Jean-Jacques Rouby and Adrien Bouglé
    Citation: Annals of Intensive Care 2022 12:43
  19. The impact of underlying comorbidities on the clinical presentation, management and outcomes in patients with ARDS is poorly understood and deserves further investigation.

    Authors: Emanuele Rezoagli, Bairbre A. McNicholas, Fabiana Madotto, Tài Pham, Giacomo Bellani and John G. Laffey
    Citation: Annals of Intensive Care 2022 12:42
  20. High-intensity noninvasive positive pressure ventilation (NPPV) is a novel ventilatory approach to maximally decreasing elevated arterial carbon dioxide tension (PaCO2) toward normocapnia with stepwise up-titrati...

    Authors: Zujin Luo, Zhixin Cao, Yichong Li, Jiawei Jin, Wei Sun, Jian Zhu, Na Zhao, Jichen Liu, Bing Wei, Yue Hu, Ying Zhang, Yingmin Ma and Chen Wang
    Citation: Annals of Intensive Care 2022 12:41

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:66

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:67

  21. Hyperoxia is associated with increased morbidity and mortality in the intensive care unit. Classical noninvasive measurements of oxygen saturation with pulse oximeters are unable to detect hyperoxia. The Oxyge...

    Authors: Hugues de Courson, Thomas Julien-Laferrière, Delphine Georges, Philippe Boyer, Eric Verchère and Matthieu Biais
    Citation: Annals of Intensive Care 2022 12:40
  22. The reports of an early and profound acquired immunodepression syndrome (AIDs) in ICU patients had gained sufficient credence to modify the paradigm of acute inflammation. However, despite several articles pub...

    Authors: C. de Roquetaillade, C. Dupuis, V. Faivre, A. C. Lukaszewicz, C. Brumpt and D. Payen
    Citation: Annals of Intensive Care 2022 12:39
  23. Central venous catheter (CVC) insertion complications are a prevalent and important problem in the intensive care unit (ICU), and source control by immediate catheter removal is considered urgent in patients w...

    Authors: Yiyue Zhong, Liehua Deng, Limin Zhou, Shaoling Liao, Liqun Yue, Shi Wu Wen, Rihua Xie, Yuezhen Lu, Liangqing Zhang, Jing Tang and Jiayuan Wu
    Citation: Annals of Intensive Care 2022 12:38
  24. The COVID-19 pandemic tested the capacity of intensive care units (ICU) to respond to a crisis and demonstrated their fragility. Unsurprisingly, higher than usual mortality rates, lengths of stay (LOS), and IC...

    Authors: Jorge I. F. Salluh, Pedro Kurtz, Leonardo S. L. Bastos, Amanda Quintairos, Fernando G. Zampieri and Fernando A. Bozza
    Citation: Annals of Intensive Care 2022 12:37
  25. Patients presenting with acute hypercapnic respiratory failure due to exacerbations of chronic obstructive pulmonary disease (AECOPD) are typically managed with non-invasive ventilation (NIV). The impact of lo...

    Authors: Nicholas A. Barrett, Nicholas Hart, Kathleen J. R. Daly, Martina Marotti, Eirini Kostakou, Chris Carlin, Stephanie Lua, Suveer Singh, Andrew Bentley, Abdel Douiri and Luigi Camporota
    Citation: Annals of Intensive Care 2022 12:36
  26. External chest-wall compression (ECC) is sometimes used in ARDS patients despite lack of evidence. It is currently unknown whether this practice has any clinical benefit in patients with COVID-19 ARDS (C-ARDS)...

    Authors: Luca Bastia, Emanuele Rezoagli, Marcello Guarnieri, Doreen Engelberts, Clarissa Forlini, Francesco Marrazzo, Stefano Spina, Gabriele Bassi, Riccardo Giudici, Martin Post, Giacomo Bellani, Roberto Fumagalli, Laurent J. Brochard and Thomas Langer
    Citation: Annals of Intensive Care 2022 12:35
  27. Whether sepsis-associated diaphragm dysfunction may improve despite the exposure of mechanical ventilation in critically ill patients is unclear. This study aims at describing the diaphragm function time cours...

    Authors: Marie Lecronier, Boris Jung, Nicolas Molinari, Jérôme Pinot, Thomas Similowski, Samir Jaber, Alexandre Demoule and Martin Dres
    Citation: Annals of Intensive Care 2022 12:34
  28. Phlebitis is an important complication occurring in patients with peripheral intravascular catheters (PIVCs). The risk factors for phlebitis in the intensive care unit (ICU) was examined.

    Authors: Hideto Yasuda, Claire M. Rickard, Nicole Marsh, Ryohei Yamamoto, Yuki Kotani, Yuki Kishihara, Natsuki Kondo, Kosuke Sekine, Nobuaki Shime, Keita Morikane and Takayuki Abe
    Citation: Annals of Intensive Care 2022 12:33
  29. Varicella-zoster virus (VZV) is one of the main viruses responsible of acute encephalitis. However, data on the prognosis and neurologic outcome of critically ill patients with VZV encephalitis are limited. We...

    Authors: Adrien Mirouse, Romain Sonneville, Keyvan Razazi, Sybille Merceron, Laurent Argaud, Naïke Bigé, Stanislas Faguer, Pierre Perez, Guillaume Géri, Claude Guérin, Anne-Sophie Moreau, Laurent Papazian, René Robert, François Barbier, Frédérique Ganster, Julien Mayaux…
    Citation: Annals of Intensive Care 2022 12:32
  30. Transfers from one intensive care unit (ICU) to another ICU are associated with increased length of intensive care and hospital stay. Inter-hospital ICU transfers are carried out for three main reasons: clinic...

    Authors: Fredric Parenmark and Sten M. Walther
    Citation: Annals of Intensive Care 2022 12:31

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:60

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:63

  31. Authors: Frank Bidar, Sarah Hamada, Morgane Gossez, Remy Coudereau, Jonathan Lopez, Marie-Angelique Cazalis, Claire Tardiveau, Karen Brengel-Pesce, Marine Mommert, Marielle Buisson, Filippo Conti, Thomas Rimmelé, Anne-Claire Lukaszewicz, Laurent Argaud, Martin Cour, Guillaume Monneret…
    Citation: Annals of Intensive Care 2022 12:30

    The original article was published in Annals of Intensive Care 2022 12:21

  32. Regional citrate anticoagulation (RCA) is recommended for continuous renal replacement therapy (CRRT). However, filter life varies and premature filter clotting can occur. The aims of this explorative prospect...

    Authors: Richard Fisher, Gary W. Moore, Michael J. Mitchell, Letian Dai, Siobhan Crichton, Nuttha Lumlertgul and Marlies Ostermann
    Citation: Annals of Intensive Care 2022 12:29
  33. Authors: Jakob Wollborn and Ulrich Goebel
    Citation: Annals of Intensive Care 2022 12:28

    The original article was published in Annals of Intensive Care 2022 12:27

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:27

    The Research to this article has been published in Annals of Intensive Care 2021 11:175

  34. Authors: Thibaut Belveyre, Can Ince and Philippe Guerci
    Citation: Annals of Intensive Care 2022 12:27

    The original article was published in Annals of Intensive Care 2021 11:175

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:28

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:28

  35. Critically ill old intensive care unit (ICU) patients suffering from Sars-CoV-2 disease (COVID-19) are at increased risk for adverse outcomes. This post hoc analysis investigates the association of the Activit...

    Authors: Raphael Romano Bruno, Bernhard Wernly, Hans Flaatten, Jesper Fjølner, Antonio Artigas, Philipp Heinrich Baldia, Stephan Binneboessel, Bernardo Bollen Pinto, Joerg C. Schefold, Georg Wolff, Malte Kelm, Michael Beil, Sigal Sviri, Peter Vernon van Heerden, Wojciech Szczeklik, Muhammed Elhadi…
    Citation: Annals of Intensive Care 2022 12:26
  36. To assess in comatose patients after cardiac arrest (CA) if amplitudes of two somatosensory evoked potentials (SSEP) responses, namely, N20-baseline (N20-b) and N20–P25, are predictive of neurological outcome.

    Authors: Sarah Benghanem, Lee S. Nguyen, Martine Gavaret, Jean-Paul Mira, Frédéric Pène, Julien Charpentier, Angela Marchi and Alain Cariou
    Citation: Annals of Intensive Care 2022 12:25
  37. The clinical impact and outcomes of ventilator-associated pneumonia (VAP) have been scarcely investigated in patients with the acute respiratory distress syndrome (ARDS).

    Authors: Marc Le Pape, Céline Besnard, Camelia Acatrinei, Jérôme Guinard, Maxime Boutrot, Claire Genève, Thierry Boulain and François Barbier
    Citation: Annals of Intensive Care 2022 12:24
  38. Survivors of viral ARDS are at risk of long-term physical, functional and neuropsychological complications resulting from the lung injury itself, but also from potential multiorgan dysfunction, and the long st...

    Authors: Guillaume Eberst, Fréderic Claudé, Lucie Laurent, Aurelia Meurisse, Pauline Roux-Claudé, Cindy Barnig, Dewi Vernerey, Sophie Paget-Bailly, Kevin Bouiller, Catherine Chirouze, Julien Behr, Franck Grillet, Ophélie Ritter, Sinan Karaer, Sébastien Pili-Floury, Hadrien Winiszewski…
    Citation: Annals of Intensive Care 2022 12:23
  39. Respiratory pendelluft phenomenon, defined as intrapulmonary gas redistribution caused by asynchronous alveolar ventilation, could be potentially harmful by inducing lung injury. The aim of the present study w...

    Authors: Yi Chi, Zhanqi Zhao, Inéz Frerichs, Yun Long and Huaiwu He
    Citation: Annals of Intensive Care 2022 12:22
  40. Lymphopenia is a hallmark of severe coronavirus disease 19 (COVID-19). Similar alterations have been described in bacterial sepsis and therapeutic strategies targeting T cell function such as recombinant human...

    Authors: Frank Bidar, Sarah Hamada, Morgane Gossez, Remy Coudereau, Jonathan Lopez, Marie-Angelique Cazalis, Claire Tardiveau, Karen Brengel-Pesce, Marine Mommert, Marielle Buisson, Filippo Conti, Thomas Rimmelé, Anne-Claire Lukaszewicz, Laurent Argaud, Martin Cour, Guillaume Monneret…
    Citation: Annals of Intensive Care 2022 12:21

    The Correction to this article has been published in Annals of Intensive Care 2022 12:30

  41. Intensive care unit (ICU) admissions among older adults are expected to increase, while the benefit remains uncertain. The availability of ICU beds varies between hospitals and between countries and is an impo...

    Authors: Ran Abuhasira, Matthew Anstey, Victor Novack, Somnath Bose, Daniel Talmor and Lior Fuchs
    Citation: Annals of Intensive Care 2022 12:20
  42. Authors: Marco Ferrari, Valentina Quaresima and Felix Scholkmann
    Citation: Annals of Intensive Care 2022 12:19

    The original article was published in Annals of Intensive Care 2022 12:2

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:18

    The Letter to the Editor to this article has been published in Annals of Intensive Care 2022 12:18

  43. The concept of frailty provides an age-independent, easy-to-use tool for risk stratification. We aimed to summarize the evidence on the efficacy of frailty tools in risk assessment in COVID-19 patients.

    Authors: Máté Rottler, Klementina Ocskay, Zoltán Sipos, Anikó Görbe, Marcell Virág, Péter Hegyi, Tihamér Molnár, Bálint Erőss, Tamás Leiner and Zsolt Molnár
    Citation: Annals of Intensive Care 2022 12:17
  44. To describe health-related quality of life (HRQoL) and dyspnea of COVID-19, 2 and 12 months after an intensive care unit (ICU) stay.

    Authors: Alexandre Demoule, Elise Morawiec, Maxens Decavele, Raphaelle Ohayon, Roxane Malrin, Maria Alejandra Galarza-Jimenez, Pierantonio Laveneziana, Capucine Morelot-Panzini, Thomas Similowski, Yann De Rycke and Jesus Gonzalez-Bermejo
    Citation: Annals of Intensive Care 2022 12:16
  45. Tumor lysis syndrome (TLS) is a life-threatening complication during the treatment of malignant neoplasia. We sought to describe characteristics and predictors of acute kidney injury (AKI), remission and morta...

    Authors: Moustafa Abdel-Nabey, Anis Chaba, Justine Serre, Etienne Lengliné, Elie Azoulay, Michael Darmon and Lara Zafrani
    Citation: Annals of Intensive Care 2022 12:15
  46. Acute kidney injury (AKI) is a common disease in the intensive care unit (ICU). AKI patients with nonrecovery of renal function have a markedly increased risk of death compared with patients with recovery. The...

    Authors: Hui-Miao Jia, Li Cheng, Yi-Bing Weng, Jing-Yi Wang, Xi Zheng, Yi-Jia Jiang, Xin Xin, Shu-Yan Guo, Chao-Dong Chen, Fang-Xing Guo, Yu-Zhen Han, Tian-En Zhang and Wen-Xiong Li
    Citation: Annals of Intensive Care 2022 12:14
  47. A sequential change in body position from supine-to-both lateral positions under constant ventilatory settings could be used as a postural recruitment maneuver in case of acute respiratory distress syndrome (A...

    Authors: Rollin Roldán, Shalim Rodriguez, Fernando Barriga, Mauro Tucci, Marcus Victor, Glasiele Alcala, Renán Villamonte, Fernando Suárez-Sipmann, Marcelo Amato, Laurent Brochard and Gerardo Tusman
    Citation: Annals of Intensive Care 2022 12:13

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