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  1. Catheters are the leading source of bloodstream infections for patients in the intensive care unit (ICU). Comprehensive unit-based programs have proven to be effective in decreasing catheter-related bloodstrea...

    Authors: Jean-François Timsit, Yohann Dubois, Clémence Minet, Agnès Bonadona, Maxime Lugosi, Claire Ara-Somohano, Rebecca Hamidfar-Roy and Carole Schwebel

    Citation: Annals of Intensive Care 2011 1:34

    Content type: Review

    Published on:

  2. The diagnostic ability of computer-based methods for cardiovascular system (CVS) monitoring offers significant clinical potential. This research tests the clinical applicability of a newly improved computer-ba...

    Authors: James A Revie, David J Stevenson, J Geoffrey Chase, Christopher E Hann, Bernard C Lambermont, Alexandre Ghuysen, Philippe Kolh, Philippe Morimont, Geoffrey M Shaw and Thomas Desaive

    Citation: Annals of Intensive Care 2011 1:33

    Content type: Research

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  3. Evidence is accumulating showing that septic acute kidney injury (AKI) is different from non-septic AKI. Specifically, a large body of research points to apoptotic processes underlying septic AKI. Unravelling ...

    Authors: Patrick M Honore, Rita Jacobs, Olivier Joannes-Boyau, Jouke De Regt, Willem Boer, Elisabeth De Waele, Vincent Collin and Herbert D Spapen

    Citation: Annals of Intensive Care 2011 1:32

    Content type: Review

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  4. We hypothesized that bedside nurses perceive significant variability in the pediatric intensivist thresholds for approaching a family about withdrawal/limitation of life-sustaining therapy.

    Authors: Colleen S Gresiuk and Ari R Joffe

    Citation: Annals of Intensive Care 2011 1:31

    Content type: Research

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  5. The aging of the population has increased the demand for healthcare resources. The number of patients aged 80 years and older admitted to the intensive care unit (ICU) increased during the past decade, as has ...

    Authors: Yên-Lan Nguyen, Derek C Angus, Ariane Boumendil and Bertrand Guidet

    Citation: Annals of Intensive Care 2011 1:29

    Content type: Review

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  6. Multiple experimental and human trials have shown that microcirculatory alterations are frequent in sepsis. In this review, we discuss the characteristics of these alterations, the various mechanisms potential...

    Authors: Daniel De Backer, Katia Donadello, Fabio Silvio Taccone, Gustavo Ospina-Tascon, Diamantino Salgado and Jean-Louis Vincent

    Citation: Annals of Intensive Care 2011 1:27

    Content type: Review

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  7. Continuous infusion of vancomycin is increasingly preferred as an alternative to intermittent administration in critically ill patients. Intermittent vancomycin treatment is associated with an increased occurr...

    Authors: Herbert D Spapen, Karin Janssen van Doorn, Marc Diltoer, Walter Verbrugghe, Rita Jacobs, Nadia Dobbeleir, Patrick M Honoré and Philippe G Jorens

    Citation: Annals of Intensive Care 2011 1:26

    Content type: Research

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  8. Intravenous glutamine supplementation is standard care when parenteral nutrition is given for critical illness. There are data of a reduced mortality when glutamine supplementation is given. In addition, stand...

    Authors: Jan Wernerman

    Citation: Annals of Intensive Care 2011 1:25

    Content type: Review

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  9. Helium is a low-density inert gas whose physical properties are very different from those of nitrogen and oxygen. Such properties could be clinically useful in the adult critical care setting, especially in pa...

    Authors: J-L Diehl, V Peigne, E Guérot, C Faisy, L Lecourt and A Mercat

    Citation: Annals of Intensive Care 2011 1:24

    Content type: Review

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  10. Suspicion of sepsis in neutropenic patients requires immediate antimicrobial treatment. The initial regimen in critically ill patients should cover both Gram-positive and Gram-negative pathogens, including Pseudo...

    Authors: Matthieu Legrand, Adeline Max, Benoît Schlemmer, Elie Azoulay and Bertrand Gachot

    Citation: Annals of Intensive Care 2011 1:22

    Content type: Review

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  11. Fibroblast growth factor-23 (FGF-23), a novel regulator of mineral metabolism, is markedly elevated in chronic kidney disease and has been associated with poor long-term outcomes. However, whether FGF-23 has a...

    Authors: MaryAnn Zhang, Raymond Hsu, Chi-yuan Hsu, Kristina Kordesch, Erica Nicasio, Alfredo Cortez, Ian McAlpine, Sandra Brady, Hanjing Zhuo, Kirsten N Kangelaris, John Stein, Carolyn S Calfee and Kathleen D Liu

    Citation: Annals of Intensive Care 2011 1:21

    Content type: Research

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  12. Given the persistent shortage of organs for transplantation, new donor management strategies to improve both organ utilization and quality of procured organs are needed. Current management protocols for the ca...

    Authors: Lorraine B Ware, Tatsuki Koyama, Dean Billheimer, Megan Landeck, Elizabeth Johnson, Sandra Brady, Gordon R Bernard and Michael A Matthay

    Citation: Annals of Intensive Care 2011 1:20

    Content type: Research

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  13. Microbiologists have extensively worked during the past decade on a particular phase of the bacterial cell cycle known as biofilm, in which single-celled individuals gather together to form a sedentary but dyn...

    Authors: Christophe Bordi and Sophie de Bentzmann

    Citation: Annals of Intensive Care 2011 1:19

    Content type: Review

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  14. The primary objective of this study was to examine levels of B-type natriuretic peptide (BNP) in mechanically ventilated patients with acute lung injury and to test whether the level of BNP would be higher in ...

    Authors: Magda Cepkova, Vineet Kapur, Xiushui Ren, Thomas Quinn, Hanjing Zhuo, Elyse Foster, Michael A Matthay and Kathleen D Liu

    Citation: Annals of Intensive Care 2011 1:18

    Content type: Research

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  15. The Surviving Sepsis Campaign is a global effort to improve the care of patients with severe sepsis and septic shock. The first Surviving Sepsis Campaign Guidelines were published in 2004 with an updated versi...

    Authors: Paul E Marik

    Citation: Annals of Intensive Care 2011 1:17

    Content type: Review

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  16. ARDS is particularly characterized by pulmonary edema caused by an increase in pulmonary capillary permeability. It is considered that limiting pulmonary edema or accelerating its resorption through the modula...

    Authors: Antoine Roch, Christophe Guervilly and Laurent Papazian

    Citation: Annals of Intensive Care 2011 1:16

    Content type: Review

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  17. Urine output often is used as a marker of acute kidney injury but also to guide fluid resuscitation in critically ill patients. Although decrease of urine output may be associated to a decrease of glomerular f...

    Authors: Matthieu Legrand and Didier Payen

    Citation: Annals of Intensive Care 2011 1:13

    Content type: Review

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  18. Critically ill patients are highly variable in their response to care and treatment. This variability and the search for improved outcomes have led to a significant increase in the use of protocolized care to ...

    Authors: J Geoffrey Chase, Aaron J Le Compte, J-C Preiser, Geoffrey M Shaw, Sophie Penning and Thomas Desaive

    Citation: Annals of Intensive Care 2011 1:11

    Content type: Review

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  19. Recruitment maneuvers (RM) consist of a ventilatory strategy that increases the transpulmonary pressure transiently to reopen the recruitable lung units in acute respiratory distress syndrome (ARDS). The ratio...

    Authors: Claude Guerin, Sophie Debord, Véronique Leray, Bertrand Delannoy, Frédérique Bayle, Gael Bourdin and Jean-Christophe Richard

    Citation: Annals of Intensive Care 2011 1:9

    Content type: Review

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  20. Depression of left ventricular (LV) intrinsic contractility is constant in patients with septic shock. Because most parameters of cardiac function are strongly dependent on afterload, especially in this contex...

    Authors: Antoine Vieillard-Baron

    Citation: Annals of Intensive Care 2011 1:6

    Content type: Review

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  21. A few decades have passed since intensive care unit (ICU) beds have been available for critically ill patients with cancer. Although the initial reports showed dismal prognosis, recent data suggest that an inc...

    Authors: Elie Azoulay, Marcio Soares, Michael Darmon, Dominique Benoit, Stephen Pastores and Bekele Afessa

    Citation: Annals of Intensive Care 2011 1:5

    Content type: Review

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  22. Chest x-rays (CXRs) are the main imaging tool in intensive care units (ICUs). CXRs also are associated with concerns inherent to their use, considering both healthcare organization and patient perspectives. In...

    Authors: Vincent Ioos, Arnaud Galbois, Ludivine Chalumeau-Lemoine, Bertrand Guidet, Eric Maury and Gilles Hejblum

    Citation: Annals of Intensive Care 2011 1:4

    Content type: Review

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  23. Erythropoietin (EPO) is a 30.4 kDa glycoprotein produced by the kidney, and is mostly well-known for its physiological function in regulating red blood cell production in the bone marrow. Accumulating evidence...

    Authors: Elizabeth Moore and Rinaldo Bellomo

    Citation: Annals of Intensive Care 2011 1:3

    Content type: Review

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  24. The clinical determination of the intravascular volume can be extremely difficult in critically ill and injured patients as well as those undergoing major surgery. This is problematic because fluid loading is ...

    Authors: Paul E Marik, Xavier Monnet and Jean-Louis Teboul

    Citation: Annals of Intensive Care 2011 1:1

    Content type: Review

    Published on:

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