The critically-ill pediatric hemato-oncology patient: epidemiology, management, and strategy of transfer to the pediatric intensive care unit

Annals of Intensive Care

Table 1 Reasons for admission to the pediatric intensive care unit (PICU)

	Pediatric hemato-oncology patients without HSCT	Children post- HSCT
Postoperative care (% of PICU admission)	72% [11]	4–16% [18, 19]
Medical reason^a
Respiratory failure	26–58% [10, 15, 17, 20]	33–88% [19, 21–23]
Airway compression^b (% of respiratory failure)	0–48% [10, 17, 20]	0% [19, 21–23]
Lung disease (% of respiratory failure)	52–100%^c[10, 15, 17, 20]	100%^d[19, 21–23]
Severe sepsis/septic shock	8–36% [10, 15, 17, 20, 24]	21–36% [18, 19, 21, 23]
Neurological problem	10–31% [10, 15, 17, 20, 24]	3–20% [18, 19, 21, 25]
Renal dysfunction	5–15% [10, 15, 20]	5–8% [21, 22, 25]
Tumor lysis syndrome	5–8% [10, 15]

HSCT = hematopoietic stem cell transplantation.
^aPercentages indicate the proportion of medical admissions only; ^bairway compression by a tumor or by a mediastinal mass; ^cmainly due to infection; ^dpossible etiologies are infectious pneumonia, idiopathic pneumonia, bronchiolitis obliterans, pulmonary hemorrhage, pulmonary edema, or GVHD.