Non-invasive assessment of fluid responsiveness by changes in partial end-tidal CO2 pressure during a passive leg-raising maneuver

Annals of Intensive Care

Table 3 Predictive performance for detecting fluid responsiveness

	Threshold	Sensitivity	Specificity	PV +	PV -	LR +	LR -
ΔCO _PLR	12%	95.2%	93.7%	95.2%	93.7%	15.24	.05
[95% CI]		[76.2-99.9%]	[69.8-99.8%]	[75.5-99.9%]	[69.8-99.8%]	[13-17.9]	[0.003-0.8]
ΔPETCO _2-PLR	5%	90.5%	93.7%	95%	88.2%	14.48	.1
[95% CI]		[69.6-98.8%]	[69.8-99.8%]	[75.1-99.9%]	[62.6-98.7%]	[12-17.5]	[0.01-1]
FTc	300 ms	66.7%	81.2%	82.4%	65%	3.56	.41
[95% CI]		[43-85.4%]	[54.4-96%]	[55.6-96.5%]	[40.8-84.6%]	[2.4-5.2]	[0.1-1.3]
ΔPP _PLR	11%	66.7%	81.2%	82.4%	65%	3.56	.41
[95% CI]		[43-85.4%]	[54.4-96%]	[55.6-96.5%]	[40.8-84.6%]	[2.4-5.2]	[0.1-1.3]

ΔCO_PLR, passive leg raising induced-change in cardiac output; ΔPETCO_2-PLR, passive leg raising-induced change in partial end-tidal CO₂;, ΔPP_-PLR, passive leg raising-induced change in arterial pulse pressure; FTc, aortic blood flow corrected time; PV+, positive predictive value; PV -, negative predictive value; LR+, positive likelihood ratio; LR-, negative likelihood ratio