Table 5 Bivariate analysis of risk factors for in-hospital mortality
From: Infective endocarditis requiring ICU admission: epidemiology and prognosis
Factor | Survivors n = 145 | Non-survivors n = 103 | p |
|---|---|---|---|
Charlson score | 4.18 ± 2.80 | 5.15 ± 2.46 | 0.003 |
SAPS II | 30.99 ± 13.16 | 44.60 ± 17.95 | <0.0001 |
SAPS II > 35 | 43 (38.4 %) | 69 (61.6 %) | <0.0001 |
SOFA score | 5.65 ± 2.77 | 8.93 ± 3.91 | <0.0001 |
SOFA score >8 | 30 (33 %) | 61 (67 %) | <0.0001 |
Glasgow Coma Score <9 | 7 (17.9 %) | 32 (82.1 %) | <0.0001 |
ICU admission for septic shock | 17 (31.5 %) | 37 (68.5 %) | <0.0001 |
ICU admission for cardiogenic shock | 16 (41 %) | 23 (59 %) | 0.016 |
ICU admission for acute respiratory failure | 22 (78.6 %) | 6 (21.4 %) | 0.02 |
ICU admission for severe valvular regurgitation | 40 (87 %) | 6 (13 %) | <0.0001 |
Mitral IE | 80 (52.6 %) | 72 (47.4 %) | 0.02 |
Native IE | 121 (62.05 %) | 74 (37.95 %) | 0.03 |
Prosthetic IE | 24 (45.3 %) | 29 (54.7 %) | 0.03 |
Annular abscess | 31 (46.3 %) | 36 (53.7 %) | 0.02 |
Severe aortic regurgitation | 50 (75.8 %) | 16 (24.2 %) | 0.0009 |
Left ventricular ejection fraction (%) | 57 ± 11 | 52 ± 13 | 0.005 |
IE due to Streptococcus spp. | 72 (67.3 %) | 35 (32.7 %) | 0.01 |
IE due to MSSA | 36 (48.70 %) | 38 (51.3 %) | 0.04 |
IE due to MRSA | 4 (25 %) | 12 (75 %) | 0.005 |
Adequate antimicrobial treatment | 127 (61.7 %) | 79 (38.3 %) | 0.02 |
Surgery during ICU stay | 80 (80.8 %) | 19 (19.2 %) | <0.0001 |
Surgery (overall) | 102 (81.6 %) | 23 (18.4 %) | <0.0001 |
Adequate surgery | 65 (85.5 %) | 11 (14.5 %) | <0.0001 |