Table 2 Drug history before intensive care unit admission
From: An observational study of adult admissions to a medical ICU due to adverse drug events
Characteristics | Total (n = 743) | Preventable ADE (n = 102) | Unpreventable ADE (n = 71) | Control (n = 570) | P value | ||
|---|---|---|---|---|---|---|---|
Preventable–unpreventable | Preventable–control | Unpreventable–control | |||||
Number of drugs taken >1 month before ICU admission (median [IQR]) | 5 [2; 8] | 5 [3; 8] | 6 [4; 9] | 5 [2; 8] | 0.17 | 0.15 | 4.3 × 10−3 |
Number of drugs taken < 1 month before ICU admission (median [IQR]) | 3 [1; 5] | 4 [1; 7] | 8 [4; 12] | 2 [0; 4] | 6.0 × 10−6 | 1.6 × 10−4 | 2.2 × 10−16 |
Total number of drugs taken before ICU admission (median [IQR]) | 9 [5; 13] | 11 [7; 15] | 15 [12; 20] | 8 [4; 11] | 8.5 × 10−7 | 3.1 × 10−5 | 2.2 × 10−16 |
Number of drugs involved in the ADEa [n (%)] | 0.19 | NA | NA | ||||
1 | NA | 33 (57 %) | 29 (41 %) | NA | |||
2 | NA | 15 (26 %) | 24 (34 %) | NA | |||
≥3 | NA | 10 (17 %) | 18 (25 %) | NA | |||
Origin of prescriptions, n (%) | 2.2 × 10−16 | NA | NA | ||||
Hospital | NA | 30 (29 %) | 59 (83 %) | NA | |||
Community | NA | 19 (19 %) | 12 (17 %) | NA | |||
Otherb | NA | 53 (52 %) | 0 (0 %) | NA | |||