Table 2 Characteristics of the patients included in the individual patient data analysis

Age, years

50.0 (36.0–69.0)

45.0 (31.0–63.0)

17.6, 0.09

(N = 139)

(N = 147)

Gender, male (%)

81 (65.9)

107 (72.8)

−19.0, 0.14

APACHE III

22.0 (17.0–31.0)

24.0 (15.0–32.0)

5.1, 0.74

(N = 57)

(N = 39)

% TBSA

25.5 (12.9–52.2)

31.2 (16.5–52.2)

−5.1, 0.51

(N = 90)

(N = 110)

Dosage of heparin (U/day)

–

(30,000–100,000)

(0.0–0.0)

Dosage of NAC (mg/day)

3600 (3600–3600)

0.0 (0.0–0.0)

–

Duration of treatment

7.0 (3.0–12.0)

0.0 (0.0–0.0)

–

Baseline LIS

2.0 (0.7–2.5)

2.0 (1.2–3.0)

−26.2, 0.29

(N = 41)

(N = 39)

Baseline PaO₂/FiO₂

219.5 (158.2–316.5)

270.0 (163.5–366.5)

−18.3, 0.09

(N = 136)

(N = 141)