Characteristics of patients at H6 | Severe sepsis (n = 40) | Septic shock (n = 63) | P value |
---|---|---|---|
N | 40 | 63 | – |
Age (years), median and IQRs | 65 [56; 73] | 68 [60; 83] | NS |
Male gender, (%) | 57 | 66 | NS |
Comorbidities (%) | |||
Diabetes | 25 | 20 | NS |
Cirrhosis | 5 | 21 | <0.05 |
Vascular disease | 25 | 32 | NS |
Solid malignancies | 22 | 22 | NS |
Haematologic malignancies | 22 | 13 | NS |
Primary site of infection (%) | |||
Lung | 43 | 43 | NS |
Abdomen | 25 | 19 | NS |
Urinary tract | 7 | 14 | NS |
Soft tissue | 15 | 13 | NS |
Other | 10 | 11 | NS |
SAPS II, median and IQRs | 37 [28; 46] | 60 [46; 69] | <0.001 |
Mechanical ventilation (%) | 28 | 75 | <0.001 |
Norepinephrine | |||
n | − | 58 | − |
Dose [μg/kg/min] | − | 0.5 [0.2; 0.9] | |
Epinephrine | |||
n | − | 1 | − |
Dose [μg/kg/min] | − | 0.9 |