Table 3 Hemodynamic parameters of patients with severe sepsis or septic shock according to ICU outcome
Parameters at H6 | Survivors | MOF deaths | Late deaths | P value |
|---|---|---|---|---|
N | 64 | 17 | 22 | − |
Time of death (days) | − | 18 [12; 37] | 2 [1; 4] | c*** |
SOFA | 6 [4; 9] | 8 [5; 11] | 14 [12; 15] | a*** b ns c*** |
SAPS II | 43 [33; 54] | 51 [43; 60] | 77 [63; 91] | a*** b ns c*** |
Mechanical ventilation (%) | 67 | 75 | 90 | a ns b ns c ns |
Norepinephrine dose (μg/Kg/min) | 0.0 [0.0; 0.30] | 0.10 [0.0; 0.25] | 0.65 [0.50; 3.25] | a*** b ns c *** |
MAP (mmHg) | 73 [67; 80] | 70 [64; 78] | 70 [66; 83] | a ns b ns c ns |
CI (L/min/m2) | 2.6 [2.1; 3.3] | 2.4 [1.9; 2.8] | 2.7 [1.9; 3.5] | a ns b ns c ns |
Urinary output (mL/Kg/h) | 1.0 [0.6; 1.4] | 0.7 [0.5; 0.8] | 0.1 [0; 0.5] | a*** b ns c*** |
Lactate level (mmol/L) | 1.5 [0.9; 2.3] | 1.5 [1.2; 2.0] | 6.1 [2.7; 14.1] | a*** b ns c*** |
Gradient (°C) | ||||
Central-to-toe | 10.4 [4.6; 12.9] | 7.0 [3.7; 12.2] | 12.9 [10.5; 14.5] | a** b ns c** |
Central-to-knee | 6.8 [4.6; 8.2] | 5.2 [4.2; 7.2] | 6.7 [3.9; 9.1] | a ns b ns c ns |
Gradient (°C) | ||||
Toe-to-room | 3.9 [0.5; 7.2] | 4.0 [0.5; 9.0] | −0.2 [−1.1; 1.3] | a*** b ns c** |
Knee-to-room | 6.8 [5.1; 8.7] | 7.9 [6.4; 8.5] | 5.5 [4.1; 7.8] | a* b ns c* |
Index CRT (s) | 1.8 [1.0; 3.1] | 2.0 [1.5; 3.3] | 4.0 [2.1; 5.9] | a** b ns c ns |
Knee CRT (s) | 2.8 [1.4; 4.3] | 3.1 [2.2; 4.7] | 5.1 [2.9; 9.0] | a*** b ns c* |
Mottling score | ||||
0–1 | 51 | 12 | 7 | a*** |
2–3 | 5 | 2 | 7 | b ns |
4–5 | 1 | 1 | 4 | c* |