From: Aerosol delivery with two ventilation modes during mechanical ventilation: a randomized study
PSV (n = 8) | VCV (n = 9) | p value | |
---|---|---|---|
Pulmonary deposition (%) | 10.5 ± 3.0 (28) | 15.1 ± 5.0 (33) | 0.038 |
Right lung | 6.1 ± 1.9 (31) | 10.6 ± 5.8 (55) | 0.057 |
Penetration index | 0.75 (0.30–0.94) | 0.32 (0.16–0.77) | 0.210 |
Left lung | 4.1 (3.8–4.6) | 4.5 (2.2–5.6) | 0.885 |
Penetration index | 0.67 (0.53–0.86) | 0.74 (0.6–1.06) | 0.211 |
Right/left lung ratio | 1.39 (0.91–2.05) | 3.33 (0.7–5.38) | 0.336 |
Extrapulmonary deposition (%) | 89.5 ± 3.0 | 84.9 ± 5.0 | 0.038 |
ETT and tracheal area | 27.4 ± 6.6 (24) | 20.7 ± 6.0 (29) | 0.043 |
Expiratory filter | 23.7 ± 5.3 (22) | 22.5 ± 7.6 (34) | 0.710 |
Ventilator circuit | 34.7 ± 8.7 (25) | 38.4 ± 12.3 (32) | 0.486 |
Proximal pieces | 32.0 ± 7.4 (23) | 35.9 ± 12.5 (35) | 0.451 |
Insp–expi tubing | 2.7 ± 1.9 (70) | 2.5 ± 1.7 (68) | 0.833 |
Nebulizer retention | 3.7 ± 0.9 (24) | 3.3 ± 0.7 (21) | 0.334 |