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Table 3 Aerosol deposition in seventeen postoperative neurological patients

From: Aerosol delivery with two ventilation modes during mechanical ventilation: a randomized study

 

PSV (n = 8)

VCV (n = 9)

p value

Pulmonary deposition (%)

10.5 ± 3.0 (28)

15.1 ± 5.0 (33)

0.038

Right lung

6.1 ± 1.9 (31)

10.6 ± 5.8 (55)

0.057

 Penetration index

0.75 (0.30–0.94)

0.32 (0.16–0.77)

0.210

Left lung

4.1 (3.8–4.6)

4.5 (2.2–5.6)

0.885

 Penetration index

0.67 (0.53–0.86)

0.74 (0.6–1.06)

0.211

Right/left lung ratio

1.39 (0.91–2.05)

3.33 (0.7–5.38)

0.336

Extrapulmonary deposition (%)

89.5 ± 3.0

84.9 ± 5.0

0.038

ETT and tracheal area

27.4 ± 6.6 (24)

20.7 ± 6.0 (29)

0.043

Expiratory filter

23.7 ± 5.3 (22)

22.5 ± 7.6 (34)

0.710

Ventilator circuit

34.7 ± 8.7 (25)

38.4 ± 12.3 (32)

0.486

  Proximal pieces

32.0 ± 7.4 (23)

35.9 ± 12.5 (35)

0.451

  Insp–expi tubing

2.7 ± 1.9 (70)

2.5 ± 1.7 (68)

0.833

Nebulizer retention

3.7 ± 0.9 (24)

3.3 ± 0.7 (21)

0.334

  1. Data expressed as mean ± SD (coefficient of variation, %) or median (25–75 % IQR). Proximal pieces of the ventilator circuit included the catheter mount, the nebulizer T-piece and the proximal flow sensor
  2. P-value in italic is considered significant (p < 0.05)
  3. ETT endotracheal tube