Table 5 Characteristics of enrolled patients by geographical origin

Age, years

66 (54–74)

54 (41.3–62)

SOFA score at admission

10.8 ± 3.5

12.3 ± 3.4

SAPS II at admission

49.6 ± 18.0

53.8 ± 25.2

Incidence of shock N (%)

257 (86.5)

48 (80)

Septic source N (%)

 Abdominal

142 (47.8)

15 (25)

 Pulmonary

42 (14.1)

21 (35)

 Urinary

13 (4.4)

3 (5)

 Postoperative cardiac surgery

22 (7.4)

1 (1.7)

 Trauma

19 (6.4)

0

 Other

59 (19.9)

20 (33.3)

Days from diagnosis to enrollment N (range)

1 (0–2.0)

1.0 (0.0–1.0)

SOFA score at enrollment

11.8 ± 3.9

15.6 ± 4.7

Cardiovascular SOFA at t ₀

3.4 ± 1.2

3.2 ± 1.5

Renal SOFA at t ₀

2.2 ± 1.6

2.6 ± 1.6

Hepatic SOFA at t ₀

1.1 ± 1.2

1.9 ± 1.6

Respiratory SOFA at t ₀

2.3 ± 1.0

2.8 ± 1.1

Coagulation SOFA at t ₀

1.3 ± 1.3

1.5 ± 1.3

Inotropic score at t ₀

6.0 (0.0–20.3)

5.0 (0.0–49.3)

Lactate at t ₀, mmol/L

1.9 (1.2–2.8)

2.7 (1.5–5.2)

Platelets at t ₀, 10³/µL

84 (35.3–166.8)

90 (55.0–129.0)

SOFA score at t ₇₂

10.2 ± 5.1

13.3 ± 6.4

Cardiovascular SOFA at t ₇₂

2.2 ± 1.8

2.0 ± 1.9

Renal SOFA at t ₇₂

1.8 ± 1.8

2.2 ± 1.8

Hepatic SOFA at t ₇₂

1.1 ± 1.3

2.0 ± 1.5

Respiratory SOFA at t ₇₂

1.9 ± 0.9

2.0 ± 1.1

Coagulation SOFA at t ₇₂

1.7 ± 1.4

1.7 ± 1.2

Inotropic Score at t ₇₂

6.0 (0.0–20.3)

5.0 (0.0–49.3)

Lactates at t ₇₂, mmol/L

1.9 (1.2–2.8)

2.7 (1.5–5.2)

Platelets at t ₇₂, 10³/µL

84 (35.3–166.8)

90 (55.0–129.0)

28-day survival, N (%)

160 (58.8)

20 (34.5)

ICU survival, N (%)

170 (59)

22 (36.7)

Hospital survival, N (%)

158 (53.2)

21 (35)