Table 5 Characteristics and outcome of patients with and without H-Cl (results are number and % of patients and medians IQR)
From: Proceedings of Réanimation 2017, the French Intensive Care Society International Congress
No H-Cl (n = 156) | H-Cl (n = 257) | P | |
|---|---|---|---|
Characteristics at inclusion | |||
SAPS II (points) | 55 (46–63) | 56 (48–65) | 0.65 |
SOFA (points) | 10 (8–12) | 10 (8–12) | 0.31 |
Vasopressor dose (µg/kg/min) | 0.32 (0.20–0.66) | 0.44 (0.23–0.80) | 0.04 |
Serum creatinine (µmol/L) | 137 (79–208) | 132 (80–191) | 0.31 |
Evolution from H0 to H72 | |||
Volume of fluid resuscitation (L) | 1.4 (0.6–2.3) | 2.2 (1.1–3.9) | <0.001 |
Chloride load (all fluids) (mmol) | 287 (129–491) | 690 (293–1127) | <0.001 |
Mean pH | 7.36 (7.29–7.40) | 7.32 (7.26–7.37) | <0.001 |
≥1 episode metab. acidosis [n (%)] | 82 (53) | 204 (79) | <0.001 |
≥1 episode H-Cl acidosis [n (%)] | NA | 77 (30) | – |
≥1 episode H-Lact acidosis [n (%)] | 41 (26) | 149 (58) | <0.001 |
Outcomes | |||
AKI [n (%)] | 96 (64) | 146 (58) | 0.42 |
D28 mortality [n (%)] | 60 (38) | 95 (37) | 0.76 |