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Table 7 Univariable and multivariable Cox model of factors associated with day-60 mortality in patients (n = 211) with severe Legionnaires’ disease admitted in the ICU

From: Proceedings of Réanimation 2017, the French Intensive Care Society International Congress

 

Univariable analysis

Multivariable analysis

HR (95% CI), p value

HR (95% CI), p value

Combination therapy

 No

1

I/NR

 Yes

0.56 [0.32–0.97], p = 0.04

 

Fluoroquinolone therapy

 No

1

1

 Yes

0.38 [0.21–0.68], p = 0.001

0.39 (0.22–0.71), p = 0.002

Age > 60 years

 No

1

1

 Yes

2.74 [1.37–5.50], p = 0.004

3.22 (1.49–6.97), p = 0.003

Smoking

 No

1

1

 Yes

0.33 [0.17–0.64], p = 0.001

0.53 (0.26–1.08), p = 0.08

LODS (per point)

1.34 [1.23–1.46], p < 0.0001

1.40 (1.27–1.54), p < 0.0001

Propensity scorea (per point)

0.23 [0.09–0.57], p = 0.002

I/NR

  1. I/NR included not retained, LODS Logistic Organ Dysfunction Score, HR hazard ratio
  2. aPropensity score of fluoroquinolone-based treatment