Fig. 4

Comparison of hemodynamics between patients with a high and low bioactive adrenomedullin (bio-ADM) and b high and low lactate levels. Data presented as median with interquartile range of hemodynamic and biomarker data collected during the initial 96 h. The number (n) of patients with each measure is indicated on top of the box plot. CI cardiac index (L/min/m2), MAP mean arterial pressure (mmHg), CVP central venous pressure (mmHg), sPAP systolic pulmonary artery pressure (mmHg). Dichotomization of biomarker values was based on median lactate (1.63 mmol/L) or bio-ADM (55.7 pg/ml) during the study period. P value based on Wilcoxon rank-sum test