Table 1 Characteristics of patients
Overall | Prone | Supine | p* | |
|---|---|---|---|---|
n | 98 | 36 | 62 | |
Epidemiological data | ||||
Age (years) (SD) | 64 (18) | 59 (19) | 67 (17) | 0.08 |
Male gender, n (%) | 59 (60) | 22 (61) | 37 (60) | 0.89 |
Weight (kg) (SD) | 83 (24) | 81 (26) | 83 (24) | 0.63 |
BMI (kg/m2) (SD) | 31 (9) | 30 (10) | 31 (10) | 0.77 |
COPD, n (%) | 15 (15) | 6 (17) | 9 (15) | 0.77 |
Ischemic heart disease, n (%) | 15 (15) | 4 (11) | 11 (18) | 0.38 |
Systemic hypertension, n (%) | 60 (61) | 13 (36) | 47 (76) | 0.001 |
Diabetes, n (%) | 29 (30) | 5 (14) | 24 (39) | 0.01 |
Characteristics of ICU severity | ||||
SAPS II (SD) [17] | 53 (17) | 47 (15) | 56 (17) | 0.02 |
Septic shock (at D0), n (%) | 75 (77) | 26 (72) | 49 (79) | 0.44 |
Catecholamine infusion (at D0) | 87 (89) | 33 (92) | 54 (87) | 0.74 |
PaO2/FiO2 and ventilator settings at D0 | ||||
PaO2/FiO2 (mmHg) (SD) | 91 (39) | 74 (24) | 101 (43) | 0.0005 |
Plateau pressure (cm of water) (SD) | 24 (6) | 26 (4) | 23 (7) | 0.02 |
Tidal volume (ml) [IQR] | 446 [400–497] | 444 [400–500] | 448 [400–496] | 0.57 |
PEEP (cm of water) (SD) | 11 (4) | 13 (4) | 10 (3) | 0.0001 |
Adjunctive therapies (during ICU stay) | ||||
Inhaled nitric oxide, n (%) | 24 (24) | 13 (36) | 11 (18) | 0.04 |
NMBA, n (%) | 59 (60) | 32 (89) | 27 (43) | 0.0001 |
Characteristics of abdominal surgery | ||||
Emergent surgery, n (%) | 79 (81) | 30 (83) | 49 (79) | 0.60 |
Peritonitis, n (%) | 41 (42) | 14 (39) | 27 (43) | 0.65 |
Colonic resection, n (%) | 22 (22) | 4 (11) | 18 (29) | 0.04 |
Small bowel resection, n (%) | 27 (28) | 9 (25) | 18 (29) | 0.67 |
Gastric resection, n (%) | 8 (8) | 4 (11) | 4 (6) | 0.46 |
Esophageal resection, n (%) | 7 (7) | 3 (8) | 4 (6) | 0.71 |
Cholecystectomy n (%) | 11 (11) | 5 (14) | 6 (10) | 0.53 |
Partial hepatectomy, n (%) | 3 (3) | 2 (6) | 1 (2) | 0.28 |
Splenectomy, n (%) | 1 (1) | 0 (0) | 1 (2) | 1.00 |
Partial pancreatectomy, n (%) | 3 (3) | 0 (0) | 3 (5) | 0.30 |
Hysterectomy, n (%) | 1 (1) | 0 (0) | 1 (2) | 1.00 |
Parietal resection, n (%) | 8 (8) | 5 (14) | 3 (5) | 0.14 |
Cesarean, n (%) | 3 (3) | 2 (6) | 1 (2) | 0.55 |
HIPEC, n (%) | 1 (1) | 0 (0) | 1 (2) | 1.00 |
≥1 stoma, n (%) | 34 (35) | 10 (28) | 24 (39) | 0.27 |
Colonic stoma, n (%) | 15 (15) | 2 (6) | 13 (21) | 0.04 |
Small bowel stoma, n (%) | 16 (16) | 6 (17) | 10 (16) | 0.95 |
Jejunostomy, n (%) | 5 (5) | 2 (6) | 3 (5) | 1.00 |
Gastrostomy, n (%) | 1 (1) | 0 (0) | 1 (2) | 1.00 |
Open abdomen, n (%) | 4 (4) | 1 (3) | 3 (5) | 1.00 |