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Table 3 MR-proADM cut-off (nmol/L) with the highest accuracy for predicting 28-day mortality based on SOFA score

From: Superior accuracy of mid-regional proadrenomedullin for mortality prediction in sepsis with varying levels of illness severity

 

Cut-off

Sensitivity

Specificity

PPV

NPV

+LR

−LR

SOFA < 6

1.79

83.0

61.0

23.8

96.2

2.14

0.27

SOFA 7–12

3.25

83.0

52.0

43.4

87.0

1.74

0.33

SOFA ≥ 13

5.58

83.8

60.0

75.6

71.4

2.09

0.27

  1. PPV positive predictive value, NPV negative predictive value, +LR positive likelihood ratio, −LR negative likelihood ratio