Outcomes | Unmatched groups | Matched groups | ||||
---|---|---|---|---|---|---|
Control (n = 3071) | Antithrombin (n = 152) | P value | Control (n = 103) | Antithrombin (n = 103) | P value | |
Ventilator-free days | 23.1 (10.0) | 15.2 (13.2) | <0.001 | 12.6 (12.9) | 16.4 (12.8) | 0.04 |
Post-admission complications | ||||||
 Intracranial haemorrhage | 9 (0.3) | 2 (1.3) | 0.09 | 0 (0) | 0 (0) | NA |
 Gastrointestinal bleeding | 19 (0.6) | 0 (0) | 1.0 | 2 (1.9) | 0 (0) | 0.50 |
 Thrombotic disorders | 22 (0.7) | 0 (0) | 0.62 | 1 (1.0) | 0 (0) | 1.0 |
 Acute renal failure | 116 (3.8) | 26 (17.1) | <0.001 | 13 (12.6) | 18 (17.6) | 0.43 |