Table 7 Characters of ATN, RENAL and IVOIRE studies
ATN | RENAL | IVOIRE | |
|---|---|---|---|
Design | Multicenter RCT | Multicenter RCT | Multicenter RCT |
Country | USA | Australia and New Zealand | France, Belgium and Netherlands |
Patients | AKI | AKI | AKI with septic shock |
No. of patients | 1124 | 1508 | 140 |
Modality | CVVHDF, SLED, IHD | CVVHDF | CVVH |
Prescribed dose | CVVHDF: 21.5 versus 36.2 ml/kg/h SLED and IHD: 3 versus 6/wk | 25 versus 40 ml/kg/h | 35 versus 70 ml/kg/h |
Delivered dose | CVVHDF: 22 versus 35.8 ml/kg/h SLED: 2.9 versus 6.2/wk IHD: 3 versus 5.4/wk | 22 versus 33.4 ml/kg/h | 33.2 versus 65.6 ml/kg/h |
Mortality | 60 days 51.5 versus 53.6% | 90 days 44.7 versus 44.7% | 90 days 50.7 versus 56.1% |