Table 1 Main characteristics of the population
Variable | All patients n = 470 | No ESBL colonization n = 408 | ESBL colonization n = 62 | p |
|---|---|---|---|---|
Age (years) | 66.0 [54.0, 77.0] | 66 [54, 77] | 68 [57, 78] | 0.5 |
Age > 65 years | 256 (54.5) | 218 (53.4) | 38 (61.3) | 0.3 |
Male gender | 283 (60.2) | 245 (60.0) | 38 (61.3) | 0.9 |
SAPS II | 46.0 [32.0, 62.0] | 45 [32, 62] | 49 [37.3, 55.5] | 0.5 |
SOFA score | 7.0 [4.0, 9.0] | 6 [4, 9] | 7 [4.5, 8.5] | 0.6 |
Preexisting conditions | ||||
Heart failure | 65 (13.9) | 53 (13.0) | 12 (19.3) | 0.2 |
Peripheral arterial disease | 60 (12.8) | 45 (11.0) | 15 (24.2) | 0.007 |
Diabetes | 110 (23.5) | 91 (22.3) | 19 (36.8) | 0.2 |
Cirrhosis | 21 (4.5) | 18 (4.4) | 3 (4.8) | 0.8 |
Chronic obstructive pulmonary disease | 69 (14.7) | 59 (14.4) | 10 (16.1) | 0.9 |
Chronic kidney disease | 61 (13.0) | 52 (12.7) | 9 (14.5) | 0.8 |
Immunosuppression | 75 (16.0) | 62 (15.2) | 12 (19.3) | 0.5 |
Mechanical ventilation | 283 (60.2) | 248 (60.8) | 35 (56.5) | 0.6 |
Catecholamine use | 224 (47.8) | 190 (46.6) | 34 (54.8) | 0.3 |
Duration of mechanical ventilation (days) | 2.0 [0.0, 5.0] | 2.0 [0.0, 5.0] | 1.0 [0.0, 4.0] | 0.4 |
ICU length of stay (days) | 4.0 [2.0, 8.0] | 4 [2.0, 8.0] | 4.0 [3.0, 8.0] | 0.8 |
Transfer from another unit | 239 (50.9) | 206 (50.5) | 33 (53.2) | 0.8 |
Postoperative care | 109 (23.2) | 94 (23.0) | 14 (22.6) | 0.9 |
Hospitalization within the previous 3 months | 243 (51.7) | 204 (50) | 39 (62.9) | 0.08 |
Antibiotics within the previous 3 months | 81 (17.2) | 68 (16.7) | 13 (20.1) | 0.5 |
Antibiotics during ICU | 346 (73.6) | 303 (74.3) | 43 (69.3) | 0.5 |
Duration of antibiotic therapy | 3.0 [0.0, 6.0] | 3.0 [0.0, 6.0] | 3.0 [0.0, 7.0] | 0.8 |
Mortality | 62 (13.2) | 56 (13.7) | 6 (9.7) | 0.2 |