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Table 2 Cardiovascular findings in the 47 patients with fulminant clinically suspected myocarditis on MCS

From: Diagnostic yield, safety and therapeutic consequences of myocardial biopsy in clinically suspected fulminant myocarditis unweanable from mechanical circulatory support

Variables

n = 47

Time from symptoms onset to hospital admission, days

3 [0–14]

Myocarditis syndrome

47 (100)

 Acute chest pain

19 (40)

 Flu-like illness

35 (74)

 Cardiogenic shock

47 (100)

 Cardiac arrest

15 (32)

  Out-of-hospital

1 (2)

  Shockable rhythm

3/15 (20)

  No-flow duration, min

0 [0–0]

  Low-flow duration, min

10 [2–22]

Elevated biomarkers

46 (98)

 Troponin highest value, fold over ULN

110 [39–325]

Electrocardiographic anomalies

40 (85)

 ST-segment depression

5 (11)

 ST-segment elevation

17 (36)

 Rhythm disorders

22 (47)

  Supraventricular

13/22 (59)

  Ventricular

9/22 (41)

 Conduction disorders

22 (47)

  Complete heart-block

7/22 (32)

Echocardiographic anomalies

47 (100)

  LVEF lowest value, %

5 [5–10]

  LVOT VTI lowest value, %

5 [0–6]

  Left ventricle involvement

47 (100)

  Right ventricle involvement

28 (62)

  Pericardial effusion

23 (49)

  LVEDD, mm

55 [52–60]

Coronary angiography

31 (66)

 No coronary obstruction

31 (100)

CMR myocarditis pattern

6/9 (67)

Bonaca classificationa after noninvasive work-up

 Definite myocarditis

6 (13)

 Probable myocarditis

41 (87)

  1. Continuous variables are expressed as median [interquartile range 25–75]; categorical variables are expressed as No. (%)
  2. MCS mechanical circulatory support, ULN upper limit of normal value, LVEF left ventricle ejection fraction, LVOT VTI left ventricular outflow tract velocity–time integral, LVEDD left ventricle end-diastolic diameter, CMR cardiac magnetic resonance
  3. aBonaca classification is available in [11]