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Annals of Intensive Care

Table 2 Clinical, echographic, and biological characteristics of cardiogenic shock patients included

From: Mottling as a prognosis marker in cardiogenic shock

 

Overall (n = 660)

 

No mottling (n = 404)

 

Mottling (n = 256)

p

Admission unit, n (%)

      

0.007

 CICU

356

69.1

235

73.4

121

62.1

 

 Reanimation

159

30.9

85

26.6

74

37.9

 

Clinical presentation at admission

       

 Heart rate (bpm), mean ± SD

95.8

 ± 30.0

93.8

 ± 26.0

99

 ± 35.2

0.029

 n

659

403

256

 

 SAP (mmHg), mean ± SD

101

 ± 25

103

 ± 23

97

 ± 27

 < 0.001

 n

660

404

256

 

 DAP (mmHg), mean ± SD

63

 ± 18

65

 ± 17

60

 ± 18

 < 0.001

 n

659

403

256

 

 Sinus rhythm, n (%)

336/659

51.0

215/403

53.4

121/256

47.3

0.128

 Cardiac arrest, n (%)

73

11.1

38

9.4

35

13.7

0.089

Blood tests at admission

       

 Sodium (mmol/L), mean ± SD

135

 ± 6

135

 ± 6

135

 ± 6

0.608

 n

652

399

253

 

 eGFR (mL/min/1.73 m2), mean ± SD

49.5

 ± 26.2

50.8

 ± 27.6

47.4

 ± 23.8

0.112

 n

644

396

248

 

 Bilirubin (mg/L), median (IQR)

16 (9–28)

16 (9–27)

17 (10–32)

0.159

 n

461

281

180

 

 Hamoglobin (g/dL), mean ± SD

12.5

 ± 2.5

12.5

 ± 2.3

12.5

 ± 2.5

0.808

 n

649

398

251

 

 Arterial blood lactates (mmol/L), median (IQR)

3.0 (2.0–5.0)

2.5 (2.0–4.0)

3.8 (2.0–6.0)

 < 0.001

 n

595

357

238

 

 ASAT (IU/L), median (IQR)

91 (38–304)

83 (37–270)

118 (42–388)

0.077

 n

458

288

170

 

 ALAT (IU/L), median (IQR)

59 (26–184)

57 (25–179)

69 (31–236)

0.074

 n

468

292

176

 

 Nt proBNP (pg/mL), median (IQR)

8938 (3894–24,363)

8388 (3466–20,333)

9277 (4411–30,000)

0.399

 n

185

111

74

 

 BNP (pg/mL), median (IQR)

1211 (484–2852)

1437 (509–2997)

1099 (484–2262)

0.236

 n

234

153

81

 

 CRP (mg/L), median (IQR)

28 (10–64)

26 (9–56)

32 (10–95)

0.111

 n

352

225

127

 

Baseline echography

       

 LVEF (%), mean ± SD

26.2

 ± 13.2

26.8

 ± 12.6

25.3

 ± 14.1

0.160

 n

653

400

253

 

 TAPSE (mm), mean ± SD

13.5

 ± 5.1

13.9

 ± 5.1

12.9

 ± 5.2

0.132

 n

235

148

87

 

 PSVtdi (cm/s), median (IQR)

8 (6–11)

8 (6–11)

9 (6–11)

0.443

 n

191

121

70

 

 Severe mitral regurgitation, n (%)

94/631

14.9

64/388

16.5

30/243

12.4

0.154

 Severe aortic stenosis, n (%)

32/650

4.9

14/399

3.5

18/251

7.2

0.036

 Severe aortic regurgitation, n (%)

9/647

1.4

4/398

1.0

5/249

2.0

0.316

  1. Values in italics indicate the number of patients included in the statistical analysis
  2. ALAT, alanine aminotransferase; ASAT, aspartate aminotransferase; CICU, cardiologic intensive care unit; CRP, C-reactive protein; DAP, diastolic arterial pressure; IQR, interquartile range; LVEF, left ventricular ejection fraction; PSVtdi, peak systolic velocity tissue Doppler imaging; SAP, systolic arterial pressure; SD, standard deviation; TAPSE, tricuspid annular plane systolic excursion
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