Table 1 Characteristics of the study population upon inclusion
Characteristics | Overall N = 40 | Extubation failure N = 12 | Extubation success N = 28 | p-value |
|---|---|---|---|---|
Age, years | 59 (48–67) | 59 (49–68) | 59 (48–65) | 0.885 |
Female sex, n (%) | 11 (28) | 4 (33) | 7 (25) | 0.877 |
Body mass index, kg.m−2 | 27 (23–31) | 27 (23–30) | 27 (23–31) | 0.735 |
24 h fluid balance, L | − 1.1 (− 2.1–0.2) | − 1.0 (− 1.9 to − 0.1) | − 1.3 (− 2.1–0.2) | 0.851 |
SOFA score | 8 (4–11) | 6 (4–8) | 8 (4–12) | 0.075 |
SAPS II | 52 (40–66) | 43 (36–54) | 54 (44–71) | 0.024 |
Days of ventilation before extubation | 10 (6–15) | 10 (7–14) | 10 (5–15) | 0.871 |
Extubation failure risk factors, n (%) | ||||
Age > 65 years old | 12 (30) | 4 (33) | 8 (29) | 1.000 |
Chronic cardiac disease | 17 (42) | 4 (33) | 13 (46) | 0.443 |
Chronic respiratory disease | 24 (60) | 5 (42) | 19 (68) | 0.166 |
Main reason for intubation, n (%) | ||||
Acute respiratory failure | 25 (62) | 10 (83) | 15 (54) | 0.154 |
Cardiac arrest | 6 (15) | 0 (0) | 6 (21) | 0.153 |
Coma | 6 (15) | 1 (8) | 5 (18) | 0.648 |
Shock | 2 (5) | 1 (8) | 1 (4) | 0.515 |
Other | 1 (2) | 0 (0) | 1 (4) | > 0.999 |
Ventilator settings | ||||
Vt PBW, ml.kg−1 | 7.2 (6.0–8.5) | 6.9 (5.6–7.5) | 7.5 (6.1–8.8) | 0.220 |
Pressure support, cmH2O | 10 (8–12) | 10 (8–12) | 10 (8–12) | 0.773 |
PEEP, cmH2O | 5 (5–6) | 5 (5–6) | 6 (5–6) | 0.275 |