Table 1 Overview on participants and acute symptomatic seizures
Structural etiology, n = 122 | Non-structural etiology, n = 19 | p, uncorrected | ||
|---|---|---|---|---|
Sex | Female | 54 (44%) | 5 (26%) | 0.21 |
Male | 68 (56%) | 14 (74%) | ||
Age [years] | 63 (54–76) | 56 (46–75) | 0.14 | |
Inpatient treatment | ICU | 64 (52%) | 4 (21%) | < 0.001 |
IMC | 16 (13%) | 4 (21%) | ||
Stroke unit/telemetry unit | 36 (30%) | 3 (16%) | ||
General ward | 6 (5%) | 8 (42%) | ||
Mechanical ventilation | Ventilation | 43 (35%) | 2 (11%) | 0.03 |
No ventilation | 79 (65%) | 17 (89%) | ||
Sepsis | Sepsis | 6 (5%) | 3 (16%) | 0.10 |
No sepsis | 116 (95%) | 16 (84%) | ||
SAPS II | 26 (19–35); n = 39* | 28 (15–36); n = 6* | 0.64 | |
Initial mRS | 3 (1–5) | 1 (0–3) | 0.19 | |
Acute symptomatic seizure as initial symptom of underlying pathology | Initial symptom | 64 (52%) | 14 (74%) | 0.14 |
Not initial symptom | 58 (48%) | 5 (26%) | ||
Delay between manifestation of underlying pathology and acute symptomatic seizure | < 24 h | 85 (70%) | 17 (90%) | 0.10 |
> 24 h | 37 (30%) | 2 (10%) | ||
Acute symptomatic seizure type | Tonic–clonic | 84 (69%) | 16 (84%) | 0.28 |
Other than tonic–clonic | 38 (31%) | 3 (16%) | ||
Single vs. multiple acute symptomatic seizures | Single seizure | 74 (61%) | 14 (74%) | 0.35 |
Multiple, within 24 h after first seizure | 26 (21%) | 4 (21%) | ||
Multiple, beyond 24 h after first seizure | 22 (18%) | 1 (5%) | ||
Inpatient EEG | Epileptiform activity | 12 (10%) | 1 (5%) | 0.69 |
No epileptiform activity | 92 (75%) | 16 (84%) | ||
EEG not performed | 18 (15%) | 2 (11%) |