Table 3 Comparison of individual pharmacokinetic parameter estimates of patients with and without ACLF

Number of patients

9

9

n/a

Body clearance (L/h)

6.26 (2.43)

1.54 (0.52)

 < 0.001

Central volume of distribution (L)

34.0 (9.04)

26.3 (11.3)

 < 0.001

RRT clearance (L/h)

1.58 (0.403)

1.78 (0.61)

0.203

Peripheral volume of distribution (L)

122 (172)

110 (161)

0.463

Inter-compartmental clearance (L/h)

9.58(0)

9.58 (0)

n/a