Table 1 Baseline characteristics
Characteristics | All (n = 254) | CTRL (n = 200) | EXT (n = 54) | P-value |
|---|---|---|---|---|
Age (years) | 51 (42–59) | 52 (42–60) | 50 (41–58) | 0.29 |
Male gender | 179 (70) | 141 (70) | 38 (70) | 0.98 |
Comorbidities | ||||
Hypertension | 95 (37) | 82 (41) | 13 (24) | 0.02 |
Obesity | 91 (36) | 72 (36) | 19 (35) | 0.91 |
Dyslipidemia | 86 (34) | 70 (35) | 16 (30) | 0.46 |
Smoking | 67 (26) | 54 (27) | 13 (24) | 0.66 |
Diabetes mellitus | 42 (16) | 35 (18) | 7 (13) | 0.43 |
Alcoholism | 32 (13) | 29 (14) | 3 (6) | 0.08 |
Type of ARDS | ||||
Pulmonary | 227 (90) | 176 (89) | 51 (94) | 0.23 |
Extrapulmonary | 25 (10) | 22 (11) | 3 (6) | |
ARDS etiology | ||||
Viral pneumonia | 117 (46) | 91 (46) | 26 (48) | 0.78 |
COVID-19 | 82 (32) | 64 (32) | 18 (33) | 0.85 |
Bacterial pneumonia | 37 (15) | 28 (14) | 9 (17) | 0.62 |
Pneumonia without SPD | 36 (14) | 28 (15) | 8 (15) | 0.88 |
Lung contusion | 25 (10) | 19 (10) | 6 (11) | 0.72 |
Extrapulmonary sepsis | 14 (6) | 12 (6) | 2 (4) | 0.74 |
Other | 25 (10) | 22 (11) | 3 (6) | 0.23 |
Pre-ECMO course (days) | ||||
Hospital to ECMO | 4.0 (1.0–8.0) | 4.0 (1.0–8.0) | 4.0 (1.0–7.0) | 0.33 |
IMV to ECMO | 2.5 (1.0–6.0) | 3.0 (1.0–6.0) | 2.0 (1.0–5.0) | 0.07 |
Pre-ECMO management | ||||
NMB | 245 (98) | 193 (97) | 52 (98) | 1.00 |
Prone position | 198 (79) | 154 (78) | 44 (83) | 0.41 |
ECMO retrieval | 173 (68) | 134 (67) | 39 (72) | 0.46 |
SAPS II | 46 (34–57) | 49 (36–60) | 39 (24–54) | < 0.01 |
SOFA | 8.0 (5.0–11) | 8.0 (6.0–12) | 7.0 (4.0–9.0) | < 0.01 |
Murray score | 3.3 (3.0–3.7) | 3.3 (3.0–3.7) | 3.3 (3.0–3.5) | 0.21 |
RESP score | 3.0 (1.0–5.0) | 3.0 (1.0–5.0) | 4.0 (1.0–5.0) | 0.12 |