Table 1 Admission characteristics and subsequent outcomes
Variable | Total cohort (N = 761) |
|---|---|
Demographics | Â |
Age, years | 45 (34–53) |
Male sex, n(%) | 449 (59) |
Body mass index (kg/m2) | 27.78 (24.2–33.6) |
Clinical parameters | Â |
APACHE II score | 17 (14–21) |
Peak pressure (cmH2O) | 22 (20–27) |
Positive end expiratory pressure (cmH2O) | 10 (10–10) |
Dynamic compliance (ml/cmH2O) | 12.5 (5.6–21) |
Heart rate (BPM) | 97 (82–112.5) |
Mean arterial pressure (mmHg) | 80 (70–90) |
Lactate (mmol/L) | 1.95 (1.3–3.7) |
Haemoglobin (g/L) | 98 (87–112) |
Platelets (× 109/L) | 180.5 (106.5–256) |
International normalized ratio | 1.1 (1–1.2) |
Bilirubin (µmol/l) | 13 (8–23) |
Creatinine (µmol/l) | 110.5 (64–192.75) |
C-reactive protein (mg/L) | 200 (87–315) |
Diagnostic category | Â |
Asthma, n(%) | 41 (5.4) |
Extrapulmonary ARDS, n(%) | 54 (7.1) |
Non-infectious pulmonary ARDS, n(%) | 50 (6.6) |
 Pulmonary vasculitis | 22 (2.9) |
 Inflammatory or interstitial lung disease | 28 (3.7) |
Infectious pulmonary ARDS, n(%) | 532 (69.9) |
 Pneumonia (aspiration) | 37 (4.9) |
 Pneumonia (bacterial) | 222 (29.2) |
 Pneumonia (viral) | 273 (35.9) |
Other, n(%) | 84 (11.0) |
 Trauma | 25 (3.3) |
 Inhalation injury | 8 (10.5) |
 Obstetrics | 3 (0.4) |
 Pulmonary Embolism | 7 (0.9) |
 Other diagnoses | 41 (5.4) |
Outcome | Â |
ECMO ICU Length of stay (days) | 19 (12–31) |
ECMO ICU Mortality, n(%) | 144 (18.9) |