Table 1 Baseline characteristics in 863 ARDS patients with and without cirrhosis
Characteristics | Total (%) (n = 863) | Patients with cirrhosis (n = 157) | Patients without cirrhosis (n = 706) | p value |
|---|---|---|---|---|
Age (years) | 60 (± 15) | 56 (± 11) | 62 (± 15) | < 0.001 |
Sex | 0.10 | |||
Male | 597 (69%) | 119 (76%) | 478 (68%) | |
Female | 266 (31%) | 38 (24%) | 228 (32%) | |
BMI (kg/m2), mean (± SD) | 25.9 (± 5.9) | 25.2 (± 5.4) | 26.0 (± 5.8) | 0.24 |
SAPS II, mean (± SD) | 52 (± 18) | 53 (± 18) | 52 (± 18) | 0.62 |
SOFA, mean (± SD)a | 11 (± 4) | 13 (± 4) | 10 (± 4) | < 0.001 |
Non-hepatic SOFA, mean (± SD)a | 10 (± 4) | 11 (± 3) | 9 (± 4) | < 0.001 |
Hepatic SOFA, mean (± SD)a | 1 (± 1) | 2 (± 1) | 1 (± 1) | < 0.001 |
Cause of ARDS | 0.01 | |||
Medical | 480 (56%) | 102 (65%) | 378 (54%) | |
Postoperative | 383 (44%) | 55 (35%) | 328 (46%) | |
Origin of ARDS | 0.41 | |||
Pulmonary | 479 (55%) | 82 (52%) | 397 (56%) | |
Pneumonia | 204 (24%) | 36 (23%) | 168 (24%) | 0.80 |
Extrapulmonary | 384 (45%) | 75 (48%) | 309 (44%) | |
Severity of ARDS | 0.04 | |||
Mild | 315 (36%) | 45 (28%) | 270 (39%) | |
Moderate | 425 (49%) | 83 (53%) | 342 (48%) | |
Severe | 123 (14%) | 29 (19%) | 94 (13%) | |
PaO2/FiO2 (mmHg), mean (± SD) | 180 (± 95) | 168 (± 82) | 183 (± 97) | 0.58 |
PaCO2 (mmHg), mean (± SD) | 40 (± 4) | 40 (± 4) | 40 (± 4) | 0.84 |
Lactate, mean (± SD) | 2.1 (± 1) | 3.2 (± 2) | 1.9 (± 1) | 0.01 |
pH, mean (± SD) | 7.33 (± 0.13) | 7.30 (± 0.16) | 7.33 (± 0.12) | 0.15 |
Bicarbonate (mmol/L), mean (± SD) | 24 (± 13) | 22 (± 5) | 24 (± 14) | 0.17 |