Table 3 Description of patients before and after matching with patients with respiratory failure from other etiologies
From: Prognosis of critically ill immunocompromised patients with virus-detected acute respiratory failure
Before matching | After matching | ||||
|---|---|---|---|---|---|
Viral–ARF N = 370 | Other ARF N = 2697 | Absolute standardized mean difference | Other ARF N = 1110 | Absolute standardized mean difference | |
Age, years | 60 (14) | 60 (15) | 0.004 | 60 (15) | 0.014 |
Female gender | 147 (39) | 1018 (38) | 0.036 | 418 (38) | 0.037 |
Chronic respiratory disease | 61 (17) | 604 (24) | 0.176 | 235 (23) | 0.135 |
Tobacco use | 66 (23) | 642 (33) | 0.222 | 241 (32) | 0.214 |
Charlson score | 4 (2) | 5 (3) | 0.319 | 5 (3) | 0.209 |
PS score ≥ 2 | 141 (43) | 1124 (49) | 0.119 | 492 (50) | 0.138 |
Underlying conditions | |||||
Immunosuppression category | 0.465 | 0.039 | |||
Hematological malignancy | 234 (63) | 1589 (59) | 673 (60) | ||
Acute leukemia | 69 (19) | 705 (26) | 224 (20) | ||
Lymphoma | 82 (22) | 565 (21) | 269 (24) | ||
Multiple myeloma | 68 (18) | 181 (7) | 107 (9) | ||
Others | 15 (4) | 138 (5) | 73 (6) | ||
Solid tumor | 52 (23) | 685 (25) | 261(23) | ||
Other | 84 (14) | 423 (16) | 176 (16) | ||
Solid organ transplant | 40 (11) | 226 (8) | 105 (14) | ||
Drugs | 44 (12) | 685 (7) | 156 (9) | ||
Allogeneic–HCT | 57 (15) | 265 (10) | 161 (15) | ||
Neutropenia | 146 (40) | 820 (30) | 0.191 | 407 (37) | 0.058 |
ICU admission | |||||
Invasive mechanical ventilation | 95 (26) | 714 (27) | 0.027 | 268 (24.5) | 0.028 |
NIV | 105 (28) | 658 (25) | 0.089 | 258 (23) | 0.116 |
High-flow oxygen | 116 (31) | 643 (24) | 0.169 | 369 (33) | 0.040 |
PaO2/FiO2, mmHg | 141 (67) | 165 (91) | 0.302 | 140 (66) | 0.013 |
SOFA score | 7 (4) | 7 (4) | 0.032 | 7 (4) | 0.002 |
ICU stay | |||||
Invasive mechanical ventilation (overall) | 141 (38) | 1239 (46) | 0.160 | 488 (44) | 0.120 |
Vasopressor support | 202 (55) | 1454 (54) | 0.013 | 597 (54) | 0.014 |
RRT | 64 (17) | 522 (19) | 0.055 | 189 (17) | 0.004 |
Outcomes | |||||
Treatment withdrawal | 103 (28) | 738 (27) | 0.009 | 317 (29) | 0.018 |
Invasive mechanical ventilation duration, days | 14 (14) | 8 (14) | 0.076 | 13 (17) | 0.021 |
ICU length of stay, days | 15 (26) | 11 (15) | 0.195 | 11 (13) | 0.215 |
Hospital length of stay, days | 24 (16.53) | 27 (25) | 0.129 | 29 (28) | 0.238 |
In ICU Mortality | 113 (31) | 839 (31) | 0.012 | 359 (32) | 0.039 |
In hospital Mortality | 140 (38) | 1161 (43) | 0.106 | 490 (44) | 0.128 |