Early mobilisation in critically ill COVID-19 patients: a subanalysis of the ESICM-initiated UNITE-COVID observational study

Annals of Intensive Care

Table 2 Outcomes

	No EM n = 3076	EM n = 1114	P (unadj.)	OR /\({\varvec{\beta}}\) adjusted^a (95% CI)	P (adj.)^a
ICU length of stay	18.00 [10.00, 28.00]	16.00 [8.00, 28.00]	0.001	0.91 (− 0.47, 1.37)	0.34
Hospital length of stay	30.00 [19.00, 45.00]	26.00 [16.00, 42.00]	< 0.001	1.4 (− 0.62, 2.35)	0.24
Outcome at 60 days
Still in ICU	81 (2.6)	27 (2.4)	0.79	OR 0.76 (0.44, 1.32)	0.33
Still in hospital (not ICU)	137 (4.5)	62 (5.6)	0.16	OR 1.15 (0.79, 1.66)	0.47
Discharged home	1408 (45.8)	666 (59.8)	<0 .001	OR 1.31 (1.08, 1.58)	0.007
Transfer to other care facility ^b	239 (7.8)	63 (5.7)	0.023	OR 0.69 (0.48, 0.98)	0.036
Palliative discharge	13 (0.4)	2 (0.2)	0.38	OR 0.11 (0.01, 1.54)	0.10
Deceased	1132 (36.8)	274 (24.6)	<0 .001	OR 0.88 (0.7, 1.09)	0.24

Data are presented as n (%) or median [IQR]. OR odds ratio; CI confidence interval. Sixty-six patients in the No EM cohort and 20 in the EM cohort with unknown/undefined/other outcomes. An overview of the count of included observations and missingness for each variable is given in Additional file 1: Table S6
^a The analysis was adjusted for the following variables: demographics/admission data: sex, age; secondary comorbidities at admission: chronic cardiac disease, chronic liver disease, history of hypertension, chronic neurological disease, chronic pulmonary disease, diabetes, asthma, malignant neoplasm, chronic kidney disease, immunosuppression, thromboembolic complications at admission, infection at admission, and country; medications and supportive care during ICU stay at any point: antivirals, corticosteroids, antimalarial drugs, sedation, renal replacement therapy (RRT), inotropes/vasopressors, and tracheostomy
^b Other care facility refers to institutions where patients are transferred after hospital if they could not independently care for themselves at home due to their health condition. This may include rehabilitation facilities or residential care facilities