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Table 1 Characteristics of COVID-19 patients (N = 28)

From: Effects of CPAP and FiO2 on respiratory effort and lung stress in early COVID-19 pneumonia: a randomized, crossover study

Anthropometric measures

 

Age

65 ± 10

Female sex, N (%)

8 (29)

BMI, kg/m2

28.8 ± 4.2

Comorbidities

 Smoke history, N (%)

14 (50)

 Hypertension, N (%)

19 (68)

 Diabetis mellitus, N (%)

6 (2)

 COPD, N (%)

0 (0)

 Congestive heart failure, N (%)

0 (0)

 Chronic kidney disease, N (%)

0 (0)

COVID-19 history

 Days from symptoms onset

9 ± 3

 Days from hospital admission

3 ± 5

 Days from oxygen support

3 ± 3

 Days from CPAP

1 ± 1

 Previous awake proning, N (%)

11 (39)

Parameters at enrolment

 SOFA score

3 ± 1

 CPAP (cmH2O)

10 ± 1

 FiO2

0.5 ± 0.1

 SpO2

95 ± 5

 Respiratory rate (bpm)

24 ± 5

 WOB scalea

3 ± 1

Laboratory data

 White blood cells (109/L)

8.2 ± 3.2

 Hemoglobin (g/dL)

13.9 ± 1.5

 Platelet count (103/mcL)

214 ± 80

 D dimer (ng/mL)

919 ± 487

 C-reactive protein (mg/L)

7.9 ± 5.1

 Creatinine (mg/dL)

0.9 ± 0.2

Outcome

 ICU admission, N (%)

9 (32)

 Endotracheal intubation, N (%)

8 (29)

 In hospital death, N (%)

6 (21)

  1. BMI body mass index, COPD chronic obstructive pulmonary disease, SOFA sequential organ failure assessment, CPAP continuous positive airway pressure, FiO2 fraction of inspired oxygen, SpO2 peripheral oxygen saturation, ICU intensive care unit
  2. aNo patients showed nasal flaring, two had evident expiratory abdominal contraction, one demonstrated palpable inspiratory contraction of the sternocleidomastoid muscle