Fig. 1

Level of circulating nucleosome H3.1 in septic shock patients. Results are shown as box representing 25th-75th percentile with median and individual values. A Nucleosome concentration in healthy volunteers (n = 50) and in patients at D1-2 (n = 151), D 3–4 (n = 116) and D 6–8 (n = 78). B Association of nucleosome concentration with organ failure assessment score (SOFA) and C simplified acute physiology score. This figure represents the nucleosome concentration in patients stratified according to SOFA and SAPS II quartiles upon ICU admission. The Mann–Whitney U test and the Dunn post-hoc test were used for group and more than two group’s comparison