Fig. 5

Admission (day 1–2) nucleosome H3.1 association with 5-day mortality. A Admission level of circulating nucleosomes (day 1–2) in septic shock patients who survived or not at day-5. Results are shown as box representing 25th–75th percentile with median and individual values. The Mann–Whitney U test was used for group comparison. B Receiver operating characteristic (ROC) curve of admission nucleosomes (day 1–2) for 5-day mortality. AUC = area under the ROC C Multivariate analysis (cox proportional hazard model) at admission (day 1–2) for association with 5-day mortality. The patients were divided into two groups based on the highest quartile versus the other quartiles for Nu H3.1, Charlson score, and SOFA score