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Table 2 Nucleosome H3.1 values and Immunological parameters variations according to 28-day mortality

From: Association of pronounced elevation of NET formation and nucleosome biomarkers with mortality in patients with septic shock

Marker

Time points

Survivor

Non-survivor

p

Nu H3.1 (ng/ml)

D1/2

1333,14 (385.14–3637.92)

1919 (880.75–12,098.9)

0.006

D3/4

662 (378.59–2151.88)

1391.5 (655.8–4186.9)

0.01

D6/8

530.72 (225.9–960.4)

605.9 (429.3–1851.7)

0.12

IL-6 (pg/ml)

D1/2

745 (245–2849.50)

1859.5 (611.5–19,198.5)

0.004

D3/4

96 (40–178)

259 (86.25–484.5)

0.0002

D6/8

54.9 (31.5–106.58)

100 35.92–300.75)

0.09

mHLA-DR (ABC)

D1/2

3793 (2682–6662)

5104 (3136–8374)

0.04

D3/4

4093 (3128–7172)

3731 (2320–5924)

0.15

D6/8

7252 (4793–9939)

4762 (2700–6391)

0.009

Lymphocyte (G/L)

D1/2

0.905 (0.500–1.600)

1.05 (0.61–1.56)

0.40

D3/4

0.9 (0.600–1.215)

0.73 (0.500–1.200)

0.53

D6/8

1.03 (0.900–1.200)

1.100 (0.800–1.600)

0.76

  1. Results at different time points as median and (interquartile range). p Mann–Whitney test