Table 3 Clinical characteristics of patients with and without kidney replacement therapy

Age (years)

57 (49–62)

59 (51–67)

0.26

Males

45 (70)

16 (59)

0.31

BMI (kg/m²)

32.4 (27.6–39.2)

30.9 (26.4–33.9)

0.09

Charlson comorb. index, pts

1 (0–2)

1 (0–2)

0.71

Disease severity

 SAPS II (pts.)

41 (35–51)

37 (34–42)

 < 0.05

 SOFA—admission (pts.)

13 (10–15)

12 (11–12)

 < 0.05

 SOFA—24h (pts.)

14 (11–16)

11 (10–12)

 < 0.001

ICU procedures

 Vasopressors

64 (100)

27 (100)

1

 High Flow-Nasal-Cannula

25 (39)

10 (37)

0.86

 Non-Invasive Ventilation

29 (45)

13 (48)

0.80

 Mechanical ventilation

64 (100)

27 (100)

1

Respiratory—Management

 Prone positioning

47 (73)

19 (70)

0.77

 Neuromuscular blockade

41 (64)

16 (59)

0.67

 Inhaled nitric oxide

36 (56)

12 (44)

0.70

 Glucocorticoid therapy

59 (92)

23 (85)

0.31

 Duration of mechanical ventilation

31 (16–56)

21 (12–44)

0.08

 Tracheostomy

42 (66)

14 (52)

0.22

Complications—ICU stay

 Pulmonary embolism

8 (13)

1 (4)

0.20

 Deep vein thrombosis

8 (13)

0 (0)

0.05

 Cardiac arrest

20 (31)

7 (26)

0.61

 Neurologic

23 (36)

16 (59)

 < 0.05

Urine output, fluid balance and blood gas

 Lactate, mmol/l—admission

1.5 (0.9–2)

1.7 (1.1–2.2)

0.69

 pH, level—admission

7.33 (7.25–7.39)

7.39 (7.29–7.47)

0.06

 Base excess—admission

1.8 (− 3.2–7.1)

5.3 (0.9–8.3)

0.08

 Bicarbonate—admission

25 (22–29)

28 (24–31)

0.05

 Creatinine, mg/dl—admission

1.26 (0.81–2.62)

0.80 (0.62–1.08)

 < 0.01

 Urine output, ml—day 1

650 (183–1363)

1350 (740–1995)

 < 0.01

 Fluid balance, ml—day 1

781 (140–2897)

456 (-162–1387)

0.15

 Urine output, ml—day 2

1365 (300–2245)

2710 (1733–3130)

 < 0.001

 Fluid balance, ml—day 2

1606 (533–3372)

1039 (299–1743)

0.05

 Urine output, ml—day 3

1040 (93–2768)

2375 (2060–2970)

 < 0.01

 Fluid balance, ml—day 3

1069 (− 340–2581)

544 (50–1502)

0.56

Outcome

 Length of stay—ICU (days)

36 (17–63)

28 (16–50)

0.27

 Length of stay—hospital (days)

38 (21–65)

30 (17–56)

0.23

 28-day mortality

23 (36)

12 (44)

0.45

 90-day mortality

42 (66)

15 (56)

0.36

 ICU mortality

44 (69)

15 (56)

0.23