Table 1 Patients’ characteristics
Variables | n = 28 |
|---|---|
Male, n (%) | 16 (57%) |
Age (years) | 59 (48, 67) |
Body mass index (kg/m2) | 24.7 (22.6, 26.9) |
Diagnosis | Â |
 Pneumonia | 9 (32%) |
 Sepsis | 7 (25%) |
 Trauma | 7 (25%) |
 Postoperative | 5 (18%) |
APACHE II | 20 (16, 22) |
Mechanical ventilation days before inclusion (days) | 7 (4, 10) |
Mechanical ventilation settings at enrollment | Â |
 PS (cmH2O) | 8 (8, 10) |
 PEEP (cmH2O) | 5 (5, 5) |
 FiO2 | 0.40 (0.35, 0.40) |
Ventilation parameters at enrollment | Â |
 Tidal volume (ml) | 538 (456, 618) |
 Respiratory rate (breaths/min) | 17 (14, 19) |
 Minute ventilation (L/min) | 8.5 (7.0, 11.2) |
Blood gas at enrollment | Â |
 PaO2 (mmHg) | 121 (85, 135) |
 PaO2/FiO2 | 313 (213, 381) |
 PaCO2 (mmHg) | 38.4 (34.3, 41.7) |
Respiratory mechanics | Â |
 Pmus (cmH2O) | 5.0 (2.8, 6.7) |
 PTPmus (cmH2O s min−1) | 55.9 (31.9, 79.9) |
 Ers | 16.1 (13.7, 18.7) |
 Elung | 3.8 (2.9, 5.4) |
 Ecw | 11.2 (9.3, 14.5) |
 PEEPi | 1 (0, 1) |
 P0.1 (cm H2O) | 1.6 (0.4, 2.1) |
 ∆Pocc (cm H2O) | 6.8 (3.1, 9.9) |
 PMI (cm H2O) | 0.4 (− 0.8, 1.5) |
Sedation | 10 (38%) |
 RASS | 0 (− 1, 0) |
Ventilator-free days | 4 (2, 7) |
Length of stay in ICU (days) | 19 (12, 33) |
Length of stay in hospital (days) | 29 (16, 41) |
Hospital mortality | 3 (10.7%) |