Use of airway pressure-based indices to detect high and low inspiratory effort during pressure support ventilation: a diagnostic accuracy study

Annals of Intensive Care

Table 3 Diagnostic performance for detecting low inspiratory effort

Indices	AUC	Cutoff	Sensitivity	Specificity	PPV	NPV
Classified by PTP_mus per minute (< 200 cmH₂O s min⁻¹)
P_0.1 (cmH₂O)	0.87 (0.83–0.92)^a	1.1	0.88 (0.81–0.93)	0.74 (0.64–0.82)	0.80 (0.75–0.85)	0.83 (0.75–0.88)
∆P_occ (cmH₂O)	0.93 (0.90–0.96)	5.7	0.87 (0.80–0.92)	0.85 (0.77–0.91)	0.88 (0.82–0.92)	0.84 (0.77–0.89)
PMI (cmH₂O)	0.95 (0.92–0.98)	0.0	0.96 (0.91–0.98)	0.86 (0.79–0.92)	0.90 (0.84–0.93)	0.94 (0.88–0.97)
Classified by P_mus (< 10 cmH₂O)
P_0.1 (cmH₂O)	0.90 (0.87–0.94)	1.2	0.90 (0.84–0.94)	0.78 (0.69–0.86)	0.86 (0.80–0.90)	0.84 (0.76–0.89)
∆P_occ (cmH₂O)	0.94(0.91–0.97)^a	6.2	0.88 (0.81–0.93)	0.86 (0.78–0.92)	0.90 (0.85–0.94)	0.83 (0.75–0.88)
PMI (cmH₂O)	0.89 (0.85–0.94)	0.0	0.83 (0.76–0.89)	0.88 (0.80–0.94)	0.91 (0.86–0.95)	0.78 (0.71–0.84)

95% confidence intervals are shown in parentheses for diagnostic performance measures
PTP_mus: inspiratory muscle pressure–time product; P_0.1: negative swing of airway pressure against end-expiratory airway occlusion at first 100 ms; ∆P_occ: the maximal negative swing of airway pressure against end-expiratory airway occlusion; PMI: pressure muscle index; P_mus: inspiratory muscle pressure; AUC: area under the receiver-operating-characteristics curve; PPV: positive predictive value; NPV: negative predictive value
^aSignificant difference was found compared to other indices