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Table 2 Comparisons of respiratory variables during spontaneous breathing trial and the maximal maneuver between extubation success and failure group

From: Predicting extubation in patients with traumatic cervical spinal cord injury using the diaphragm electrical activity during a single maximal maneuver

 

Overall (n = 107)

Successful extubation (n = 50)

Unsuccessful extubation (n = 57)

p value

Respiratory rate, bpm

27 (6)

24 (5)

29 (6)

 < 0.001

Baseline VT, mL/kg

4.6 [3.3, 5.5]

5.3 [4.6, 5.7]

3.3 [2.8, 5.1]

 < 0.001

Maximal VT, mL/kg

9.3 [4.9, 11.4]

11.1 [9.7, 14.1]

5.0 [3.7, 8.9]

 < 0.001

ΔVT, mL/kg

4.1 [1.7, 6.2]

6.2 [4.8, 8.7]

1.7 [1.1, 3.6]

 < 0.001

RSBI

88 [62, 140]

72 [58, 88]

137 [78, 178]

 < 0.001

Baseline EAdi, μV

5.9 [4.2, 8.0]

7.8 [6.2, 9.4]

4.3 [3.1, 5.7]

 < 0.001

Maximal EAdi, μV

14.8 [6.8, 22.5]

22.5 [19.8, 27.8]

7.5 [4.6, 10.5]

 < 0.001

Rel EAdi, %

48.5 [33.9, 58.8]

32.7 [27.7, 39.9]

57.9 [53.2, 65.6]

 < 0.001

ΔEAdi, μV

8.1 [3.0, 15.6]

15.7 [11.5, 19.0]

3.1 [1.6, 5.0]

 < 0.001

ΔEAdi, %

110 [70, 190]

210 [150, 260]

70 [50, 90]

 < 0.001

Baseline NVE, mL/μV

51.6 [40.5, 67.1]

44.1 [35.9, 52.9]

60.6 [46.4, 74.1]

 < 0.001

Maximal NVE, mL/μV

40.0 [31.5, 58.7]

32.0 [28.3, 36.5]

55.2 [41.9, 66.5]

 < 0.001

pH

7.43 [7.41, 7.45]

7.43 [7.41, 7.46]

7.43 [7.41, 7.45]

0.913

PaCO2, mmHg

36.2 [32.1, 39.8]

33.5 [30.7, 37.5]

37.8 [34.9, 41.0]

0.001

PaO2/FiO2, mmHg

306.6 [248.3, 366.2]

335.5 [285.1, 386.5]

280.0 [220.8, 349.8]

 < 0.001

Bicarbonate, mmol/L

24.0 [22.2, 26.5]

23.0 [20.8, 24.7]

25.9 [23.5, 27.6]

 < 0.001

Lac, mmol/L

1.5 [1.1, 2.2]

1.5 [0.9, 2.2]

1.6 [1.1, 2.2]

0.559

  1. EAdi, diaphragm electrical activity; Rel EAdi, relative activation of diaphragm at baseline; FiO2, fraction of inspired oxygen; NVE, neuroventilatory efficiency; RSBI, rapid shallow breathing index; VT, tidal volume normalized to predicted body weight; PaCO2, partial pressure of arterial carbon dioxide; PaO2, partial pressure of arterial oxygen