Fig. 3
From: Inhaled drug delivery: a randomized study in intubated patients with healthy lungs
Intersubject variability of aerosol deposition between the right and the left lung and its penetration through the lungs with the four configurations of aerosol delivery. A Scintigraphic images of aerosol lung deposition in four patients of the SCAT group (upper left), the HH Off group (upper right), the HH On group (lower left) and the ETT group (lower right). Patients of the SCAT and the ETT group had a variable drug deposition (predominant right or left lung deposition or symmetrical) while a symmetrical aerosol deposition is depicted in the HH Off and the HH On group. B Radiolabeled drug dose deposited in the right and the left lung for the sixteen illustrated patients. Data expressed as a percentage of the nominal dose. ETT endotracheal tube, HH heated humidifier, SCAT specific ventilator circuit for aerosol therapy