Table 1 Characteristics of older patients (≥ 80 years) admitted to the ICU with sepsis diagnosis in VIP-1 and VIP-2 studies
From: The critically ill older patient with sepsis: a narrative review
Cohorts | Sepsis VIP-1 | Sepsis VIP-2 |
|---|---|---|
N (%) | 493/3869 (12.7%) | 532/3596 (14.8%) |
Age (years) | 83 (81–86) | 84 (81–86) |
Gender (male) | 265 (53.8%) | 298 (56%) |
SOFA score at admission | 9 (6–12) | 9 (6–11) |
ICU LOS (days) | 3.54 (1.5–8) | 4.77 (2–9) |
Frailty (CFS) | ||
 Fit (CFS 1–3) | 165 (33.5%) | 195 (36.7%) |
 Vulnerable (CFS 4) | 76 (15.4%) | 89 (16.7%) |
 Frail (5–9) | 252 (51.1%) | 248 (46.6%) |
ICU interventions | ||
 Mechanical ventilation | 234 (47.5%) | 260 (49%) |
 Non-invasive ventilation | 108 (21.9%) | 86 (16.2%) |
 Vasoactive drugs | 405 (82.2%) | 456 (85.9%) |
 Renal replacement techniques | 86 (17.4%) | 109 (20.6%) |
Limitations of care | ||
 Withholding | 108 (21.9%) | 186 (35.6%) |
 Withdrawing | 76 (15.4%) | 79 (15.1%) |
Mortality | ||
 ICU | 154 (31.2%) | 166 (41.4%) |
 30 days | 220 (44.6%) |  |
 6 months |  | 286 (54%) |