Univariable model (unadjusted) | Multivariable model (adjusted *) | |||
---|---|---|---|---|
OR (95%-CI) / Regression-Co-efficient B (95%-CI) | p-value | OR (95%-CI) / Regression-Co-efficient B (95%-CI) | p-value | |
Primary endpoint | ||||
MAKE30 | 2.59 (2.25–2.99) | < 0.001 | 1.96 (1.67–2.30) | < 0.001 |
Secondary endpoints | ||||
Need for RRT | 6.27 (5.18–7.60) | < 0.001 | 3.83 (3.02–4.84) | < 0.001 |
Duration of RRT on the ICU [days] | 3.41 (2.06–4.76) | < 0.001 | 1.48 (1.14–1.82) | < 0.001 |
Acute kidney injury (AKI) | 2.18 (1.91–2.49) | < 0.001 | 1.76 (1.53–2.03) | < 0.001 |
KDIGO stage 1 | 0.88 (0.75–1.03) | 0.119 | ||
KDIGO stage 2 | 0.65 (0.43–0.98) | 0.039 | 0.60 (0.39–0.91) | 0.015 |
KDIGO stage 3 | 2.58 (2.28–2.92) | < 0.001 | 2.01 (1.76–2.31) | < 0.001 |
Persistent renal dysfunction+ | 2.54 (2.10–3.08) | < 0.001 | 1.72 (1.40–2.12) | < 0.001 |
30-day mortality | 2.04 (1.69–2.45) | < 0.001 | 1.70 (1.38–2.09) | < 0.001 |