| Medical N = 76 | Plasmapheresis N = 46 | Effect estimatea (95% CI) | P value |
---|---|---|---|---|
Primary outcome | ||||
 Time to organ failure resolution, d | 4.00 (0.25–8.75) | 4.00 (2.00–7.00) | HR, 1.07 (0.68 to 1.68) | 0.777 |
Secondary outcomes | ||||
 Requirement of ICU admission | 50 (65.8) | 45 (97.8) | OR, 19.33 (2.20 to 169.81) | 0.008 |
 28-day mortality | 2 (2.6) | 2 (4.3) | OR, 0.67 (0.04 to 11.49) | 0.785 |
 60-day mortality | 4 (5.3) | 6 (13.0) | OR, 1.84 (0.35 to 9.61) | 0.468 |
 ICU-free days to day14, d | 10.00 (2.25–14.00) | 7.00 (2.00–10.00) | β, 0.85 (− 1.94 to 3.64) | 0.547 |
 Length of hospital stay, d | 11.00 (7.00–18.75) | 14.50 (9.75–20.25) | β, − 0.99 (− 5.58 to 3.61) | 0.672 |