Spontaneous breathing trial with pressure support on positive end-expiratory pressure and extensive use of non-invasive ventilation versus T-piece in difficult-to-wean patients from mechanical ventilation: a randomized controlled trial

Annals of Intensive Care

Table 3 Additional outcomes added during the reviewing process

Variables	Extensively-assisted weaning group (n = 47)	Standard weaning group (n = 47)	Absolute rate difference [CI_95%]*	p-value
Rate of successful first SBT after inclusion—No. (%)	16 (34%)	9 (19%)	15 [− 2–32]%	0.16
Rate of successful extubation on day-1 after the first SBT—No. (%)	7 (15%)	5 (11%)	4 [− 9–17]%	0.76
Rate of successful extubation within 7 days after inclusion—No. (%)	22 (47%)	28 (60%)	− 13 [− 32–6]%	0.30
Rate of patients experiencing an extubation attempt—No. (%)	41 (87%)	44 (94%)	− 6 [− 19–4]%	0.49
Rate of patients with a self extubation among extubated patients—No. (%)	6/41 (15%)	2/44 (5%)	10 [− 2–22]%	0.15

CI_95% denotes 95% confidence interval; pts, patients; and SBT, spontaneous breathing trial
^*Absolute rate difference and CI_95% were computed for proportions using bootstrapping