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Table 2 Transthoracic echocardiography and lung and diaphragm ultrasound variables before and during the spontaneous breathing trial

From: Combined cardiac, lung, and diaphragm ultrasound for predicting weaning failure during spontaneous breathing trial

 

Before SBT

p

value

30 min after starting SBT

p

value

 

Weaning success (n = 36)

Weaning failure (n = 15)

Weaning success (n = 36)

Weaning failure (n = 15)

TTE variables

 LVEF, n (%)

  

0.624

  

0.436

 30 − 50%

5 (14)

0 (0)

 

5 (14)

0 (0)

 

 50 − 70%

28 (78)

15 (100)

 

29 (81)

15 (100)

 

 > 70%

3 (8)

0 (0)

 

2 (6)

0 (0)

 

 LVOT VTI, cm

21.9 (18.6–25.3)

20.3 (16.1–23.6)

0.247

22.4 (17.6–24.8)

21 (20.3–23.1)

0.598

 E, cm/s

83 (63–91)

69 (64–86)

0.368

80 (68–94)

76 (69–82)

0.78

 E/A

0.93 (0.78–1.17)

0.78 (0.66–0.95)

0.157

0.83 (0.71–0.95)*

0.81 (0.72–1.21)

0.718

 e’ septal, cm/s

8 (6–9)

6 (5–8)

0.161

7 (6–9)

7 (6–8)

0.582

 E/e’ septal

10.9 (7.3–13.1)

10.3 (9.6–12.3)

0.78

10.8 (8.6–13.3)

10.8 (9.1–12.4)

0.741

 e’ lateral, cm/s

10 (8–11)

9 (9–11)

0.917

10 (8–12)

9 (9–10)

0.723

 E/e’ lateral

8.1 (6.5–10.1)

7.4 (5.6–9.9)

0.508

8.1 (6.3–10.3)

7.4 (7.2–9.3)

0.975

 Average E/e’

9.2 (6.6–11.8)

9.2 (6.7–11.7)

0.893

8.9 (7.2–10.9)

9.0 (7.9–10.1)

0.984

 MAPSE, cm

1.4 (1.2–1.5)

1.4 (1.1–1.7)

0.568

1.3 (1-1.7)

1.3 (1.2–1.8)

0.474

 TAPSE, cm

2 (1.7–2.3)

1.7 (1.5–2.2)

0.501

2 (1.7–2.3)

1.8 (1.5–2.3)

0.475

 RVEDA: LVEDA ratio, n (%)

  

0.989

  

0.989

 < 0.6

27 (75)

11 (73)

 

27 (75)

11 (73)

 

 0.6–1

7 (19)

4 (27)

 

7 (19)

4 (27)

 

 > 1

2 (6)

0 (0)

 

2 (6)

0 (0)

 

LUS variables

 Global LUS score

11 (8–15)

14 (10–16)

0.246

12 (9–17)*

18 (16–20)*

0.015

 Anterior LUS score

0 (0–3)

2 (0–4)

0.285

1 (0–3)*

5 (2–6)*

0.03

 Antero-lateral LUS score

3 (2–6)

7 (4–9)

0.033

5 (2–6)*

11 (7–12)*

0.014

 Lung consolidation, n (%)

24 (67)

11 (73)

0.64

24 (67)

11 (73)

0.64

Diaphragm ultrasound variables

 DE, mm

   

12 (9–21)

10 (8–14)

0.242

 DTF, %

   

30 (12.4–36.8)

14.7 (12.5–20)

0.048

  1. SBT spontaneous breathing trial; TTE transthoracic echocardiography; LVEF left ventricle ejection fraction; LVOT left ventricular outflow tract; VTI velocity–time integral; E early mitral inflow velocity; e′ mitral annular early diastolic velocity; MAPSE mitral annular plane systolic excursion; TAPSE tricuspid annular plane systolic excursion; RVEDA right ventricular end-diastolic area; LVEDA left ventricular end-diastolic area; LUS lung ultrasound; DE diaphragm excursion; DTF diaphragm thickening fraction
  2. *p < 0.05 30 min after starting SBT vs. before SBT