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Annals of Intensive Care
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  1. The mortality rate of sepsis remains high and further increases when complicated by disseminated intravascular coagulation (DIC). Consequently, early detection and appropriate management of DIC will be helpful...

    Authors: Toshiaki Iba, Julie Helms and Jerrold H. Levy
    Citation: Annals of Intensive Care 2024 14:148
    Content type: Review Published on:

  2. Sepsis is a dysregulated immune response to an infection that leads to organ dysfunction. Sepsis-associated organ dysfunction involves multiple inflammatory mechanisms and complex metabolic reprogramming of ce...

    Authors: André Borges and Luís Bento
    Citation: Annals of Intensive Care 2024 14:147
    Content type: Review Published on:

  3. Improvements in oxygenation and lung mechanics with prone position (PP) in patients with acute respiratory distress syndrome (ARDS) are inconstant. The objectives of the study were (i) to identify baseline var...

    Authors: Christopher Lai, Rui Shi, Ludwig Jelinski, Florian Lardet, Marta Fasan, Soufia Ayed, Hugo Belotti, Nicolas Biard, Laurent Guérin, Nicolas Fage, Quentin Fossé, Thibaut Gobé, Arthur Pavot, Guillaume Roger, Alex Yhuel, Jean-Louis Teboul…
    Citation: Annals of Intensive Care 2024 14:146
    Content type: Research Published on:

  4. Acute kidney injury (AKI) is a multifactorial syndrome with a high risk of short- and long-term complications as well as increased health care costs. The traditional biomarkers of AKI, serum creatinine and uri...

    Authors: Marlies Ostermann, Matthieu Legrand, Melanie Meersch, Nattachai Srisawat, Alexander Zarbock and John A. Kellum
    Citation: Annals of Intensive Care 2024 14:145
    Content type: Review Published on:

  5. Cardiac arrest remains a global health issue with limited data on long-term outcomes, particularly regarding recurrent cardiovascular events in patients surviving out-of-hospital cardiac arrest. (OHCA). We aim...

    Authors: Sofia Ortuno, Wulfran Bougouin, Sebastian Voicu, Marine Paul, Jean-Baptiste Lascarrou, Sarah Benghanem, Florence Dumas, Frankie Beganton, Nicole Karam, Eloi Marijon, Xavier Jouven, Alain Cariou and Nadia Aissaoui
    Citation: Annals of Intensive Care 2024 14:144
    Content type: Research Published on:

  6. Maintaining the dose-intensity of cancer treatment is an important prognostic factor of aggressive hematological malignancies. The objective of this study was to assess the long-term outcomes of intensive care...

    Authors: Swann Bredin, Justine Decroocq, Clément Devautour, Julien Charpentier, Clara Vigneron and Frédéric Pène
    Citation: Annals of Intensive Care 2024 14:143
    Content type: Research Published on:

  7. Authors: Christophe Le Terrier, Thaïs Walter, Said Lebbah, David Hajage, Florian Sigaud, Claude Guérin, Luc Desmedt, Steve Primmaz, Vincent Joussellin, Chiara Della Badia, Jean Damien Ricard, Jérôme Pugin and Nicolas Terzi
    Citation: Annals of Intensive Care 2024 14:142
    Content type: Correction Published on:

    The original article was published in Annals of Intensive Care 2024 14:100

  8. Acute respiratory distress syndrome (ARDS) occurring in patients with hematological malignancies (HM) is a life-threatening condition with specific features. Mortality rate remains high but improvement has bee...

    Authors: Pierre-Nicolas Bris, Vanessa Pauly, Véronica Orleans, Jean-Marie Forel, Pascal Auquier, Laurent Papazian, Laurent Boyer and Sami Hraiech
    Citation: Annals of Intensive Care 2024 14:141
    Content type: Research Published on:

  9. Although largely used, the place of oxygen therapy and its devices in patients with acute hypoxemic respiratory failure (ARF) deserves to be clarified. The French Intensive Care Society (Société de Réanimation...

    Authors: Julie Helms, Pierre Catoire, Laure Abensur Vuillaume, Héloise Bannelier, Delphine Douillet, Claire Dupuis, Laura Federici, Melissa Jezequel, Mathieu Jozwiak, Khaldoun Kuteifan, Guylaine Labro, Gwendoline Latournerie, Fabrice Michelet, Xavier Monnet, Romain Persichini, Fabien Polge…
    Citation: Annals of Intensive Care 2024 14:140
    Content type: Research Published on:

  10. The coronavirus-related disease (COVID-19) is mainly characterized by a respiratory involvement. The renin-angiotensin system (RAS) has a relevant role in the pathogenesis of COVID-19, as the virus enters host...

    Authors: Ana Luiza Valle Martins, Filippo Annoni, Filipe Alex da Silva, Lucas Bolais-Ramos, Gisele Capanema de Oliveira, Renata Cunha Ribeiro, Mirella Monique Lana Diniz, Thuanny Granato Fonseca Silva, Beatriz Dias Pinheiro, Natália Abdo Rodrigues, Alana Helen dos Santos Matos, Daisy Motta-Santos, Maria José Campagnole-Santos, Thiago Verano-Braga, Fabio Silvio Taccone and Robson Augusto Souza Santos
    Citation: Annals of Intensive Care 2024 14:139
    Content type: Research Published on:

  11. The optimal timing of weaning from venovenous extracorporeal membrane oxygenation (VV ECMO) and its modalities have been rarely studied.

    Authors: Maria Teresa Passarelli, Matthieu Petit, Roberta Garberi, Guillaume Lebreton, Charles Edouard Luyt, Marc Pineton De Chambrun, Juliette Chommeloux, Guillaume Hékimian, Emanuele Rezoagli, Giuseppe Foti, Alain Combes, Marco Giani and Matthieu Schmidt
    Citation: Annals of Intensive Care 2024 14:138
    Content type: Research Published on:

  12. Activation of innate immunity is a first line of host defense during acute critical illness (ACI) that aims to contain injury and avoid tissue damages. Aberrant activation of innate immunity may also participa...

    Authors: Laure Stiel, Alexandre Gaudet, Sara Thietart, Hélène Vallet, Paul Bastard, Guillaume Voiriot, Mehdi Oualha, Benjamine Sarton, Hatem Kallel, Nicolas Brechot, Louis Kreitmann, Sarah Benghanem, Jérémie Joffre and Youenn Jouan
    Citation: Annals of Intensive Care 2024 14:137
    Content type: Review Published on:

  13. Severe trauma is the leading cause of disability and mortality in the patients under 35 years of age. Surgical site infections (SSI) represent a significant complication in this patient population. However, th...

    Authors: Lucie Savio, Pierre Simeone, Sophie Baron, François Antonini, Nicolas Bruder, Salah Boussen, Laurent Zieleskiewicz, Benjamin Blondel, Solène Prost, Guillaume Baucher, Marie Lebaron, Thibault Florant, Mohamed Boucekine, Marc Leone and Lionel Velly
    Citation: Annals of Intensive Care 2024 14:136
    Content type: Research Published on:

  14. Post-intensive care syndrome could be responsible for inability to receive proper cancer treatment after ICU stay in patients with solid tumors (ST). Our purpose was to determine the factors associated with ca...

    Authors: Soraya Benguerfi, Ondine Messéant, Benoit Painvin, Christophe Camus, Adel Maamar, Arnaud Gacouin, Charles Ricordel, Jean Reignier, Emmanuel Canet, Julien Edeline and Jean-Marc Tadié
    Citation: Annals of Intensive Care 2024 14:135
    Content type: Research Published on:

  15. Multiple organ failure/dysfunction syndrome (MOF/MODS) is a major cause of mortality and morbidity among severe trauma patients. Current clinical practices entail monitoring physiological measurements and appl...

    Authors: Ivan Duran, Ankita Banerjee, Patrick J. Flaherty, Yok-Ai Que, Colleen M. Ryan, Laurence G. Rahme and Amy Tsurumi
    Citation: Annals of Intensive Care 2024 14:134
    Content type: Research Published on:

  16. Optimal balance between macro- and microcirculation in critically ill patients is crucial for ensuring optimal organ perfusion. Nitric oxide (NO) is a regulator of vascular hemostasis and tone. The availabilit...

    Authors: Karoline Myglegård Mortensen, Theis Skovsgaard Itenov, Jakob Stensballe, Thore Hillig, Claus Antonio Juel Jensen, Martin Schønemann-Lund and Morten Heiberg Bestle
    Citation: Annals of Intensive Care 2024 14:133
    Content type: Research Published on:

  17. By controlling hypercapnia, respiratory acidosis, and associated consequences, extracorporeal CO2 removal (ECCO2R) has the potential to facilitate ultra-protective lung ventilation (UPLV) strategies and to decrea...

    Authors: Alain Combes, Georg Auzinger, Luigi Camporota, Gilles Capellier, Guglielmo Consales, Antonio Gomis Couto, Wojciech Dabrowski, Roger Davies, Oktay Demirkiran, Carolina Ferrer Gómez, Jutta Franz, Matthias Peter Hilty, David Pestaña, Nikoletta Rovina, Redmond Tully, Franco Turani…
    Citation: Annals of Intensive Care 2024 14:132
    Content type: Research Published on:

  19. Nitric oxide (NO) is a strong vasodilator, selectively directed on pulmonary circulation through inhaled administration. In adult intensive care units (ICU), it is mainly used for refractory hypoxemia in mecha...

    Authors: Alice Vuillermoz, Mathilde Lefranc, Nathan Prouvez, Clément Brault, Yoann Zerbib, Mary Schmitt, Jean-Marie Forel, Mathieu Le Tutour, Arnaud Lesimple, Alain Mercat, Jean-Christophe Richard and François M. Beloncle
    Citation: Annals of Intensive Care 2024 14:130
    Content type: Research Published on:

  20. This study aimed to develop prognostic models for predicting the need for invasive mechanical ventilation (IMV) in intensive care unit (ICU) patients with COVID-19 and compare their performance with the Respir...

    Authors: Gabriel Maia, Camila Marinelli Martins, Victoria Marques, Samantha Christovam, Isabela Prado, Bruno Moraes, Emanuele Rezoagli, Giuseppe Foti, Vanessa Zambelli, Maurizio Cereda, Lorenzo Berra, Patricia Rieken Macedo Rocco, Mônica Rodrigues Cruz, Cynthia dos Santos Samary, Fernando Silva Guimarães and Pedro Leme Silva
    Citation: Annals of Intensive Care 2024 14:129
    Content type: Research Published on:

  21. Mortality for patients receiving extracorporeal membrane oxygenation (ECMO) for COVID-19 increased over the course of the pandemic. We investigated the association between immunomodulators and mortality for pa...

    Authors: Ryan Ruiyang Ling, Kollengode Ramanathan, Liang Shen, Ryan P. Barbaro, Kiran Shekar, Daniel Brodie and Graeme MacLaren
    Citation: Annals of Intensive Care 2024 14:128
    Content type: Research Published on:

  22. A combination of prone positioning (PP) and venovenous extracorporeal membrane oxygenation (VV-ECMO) is safe, feasible, and associated with potentially improved survival for severe acute respiratory distress s...

    Authors: Rui Wang, Xiao Tang, Xuyan Li, Ying Li, Yalan Liu, Ting Li, Yu Zhao, Li Wang, Haichao Li, Meng Li, Hu Li, Zhaohui Tong and Bing Sun
    Citation: Annals of Intensive Care 2024 14:127
    Content type: Research Published on:

  23. The underrepresentation of women in leadership remains a pervasive issue, prompting a critical examination of support mechanisms within professional settings. Previous studies have identified challenges women ...

    Authors: Silvia De Rosa, Stefan J. Schaller, Laura Galarza, Ricard Ferrer, Bairbre A. McNicholas, Max Bell, Julie Helms, Elie Azoulay and Antoine Vieillard-Baron
    Citation: Annals of Intensive Care 2024 14:126
    Content type: Research Published on:

  26. Fluid administration is the first line treatment in intensive care unit (ICU) patients with sepsis and septic shock. While fluid boluses administration can be titrated by predicting preload dependency, the amo...

    Authors: Antonio Messina, Marco Albini, Nicolò Samuelli, Andrea Brunati, Elena Costantini, Giulia Lionetti, Marta Lubian, Massimiliano Greco, Guia Margherita Matronola, Fabio Piccirillo, Daniel De Backer, Jean Louis Teboul and Maurizio Cecconi
    Citation: Annals of Intensive Care 2024 14:123
    Content type: Research Published on:

  28. Inflammation is the hallmark of critical illness and triggers the neuro-endocrine stress response and an oxidative stress. Acute inflammation is initially essential for patient’s survival. However, ongoing or ...

    Authors: Anne-Françoise Rousseau and Robert Martindale
    Citation: Annals of Intensive Care 2024 14:121
    Content type: Review Published on:

  29. The accuracy of a diagnostic test depends on its intrinsic characteristics and the disease incidence. This study aims to depict post-test probability of Pneumocystis pneumonia (PJP), according to results of PCR a...

    Authors: Laure Calvet, Virginie Lemiale, Djamel Mokart, Schellongowski Peter, Pickkers Peter, Alexande Demoule, Sangeeta Mehta, Achille Kouatchet, Jordi Rello, Philippe Bauer, Ignacio Martin-Loeches, Amelie Seguin, Victoria Metaxa, Magali Bisbal, Elie Azoulay and Michael Darmon
    Citation: Annals of Intensive Care 2024 14:120
    Content type: Research Published on:

  30. The objective was to assess the agreement between therapeutic proposals derived from basic critical care echocardiography performed by novice operators in ultrasonography after a limited training (residents) a...

    Authors: Marine Goudelin, Bruno Evrard, Roxana Donisanu, Céline Gonzalez, Christophe Truffy, Marie Orabona, Antoine Galy, François-Xavier Lapébie, Yvan Jamilloux, Elodie Vandeix, Dominique Belcour, Charles Hodler, Lucie Ramirez, Rémi Gagnoud, Catherine Chapellas and Philippe Vignon
    Citation: Annals of Intensive Care 2024 14:119
    Content type: Research Published on:

  31. Antimicrobial stewardship (AMS) for ventilator-associated pneumonia (VAP) or ventilated hospital-acquired pneumonia (vHAP) in extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) carriers is challeng...

    Authors: Pierre Bay, Vincent Fihman, Paul-Louis Woerther, Bastien Peiffer, Ségolène Gendreau, Romain Arrestier, Pascale Labedade, Elsa Moncomble, Antoine Gaillet, Guillaume Carteaux, Nicolas de Prost, Armand Mekontso Dessap and Keyvan Razazi
    Citation: Annals of Intensive Care 2024 14:118
    Content type: Research Published on:

  32. Therapeutic plasma exchanges (TPE), which affect the humoral response, are often performed in combination with immunosuppressive drugs. For this reason, TPE may be associated with an increased susceptibility t...

    Authors: Sofiane Fodil, Tomas Urbina, Swann Bredin, Julien Mayaux, Antoine Lafarge, Louaï Missri, Eric Maury, Alexandre Demoule, Frederic Pene, Eric Mariotte and Hafid Ait-Oufella
    Citation: Annals of Intensive Care 2024 14:117
    Content type: Research Published on:

  33. To identify the prevalence and associated factors of cognitive dysfunction, 1 year after ICU discharge, among adult patients, and it´s relation with quality of life.

    Authors: Isabel Jesus Pereira, Mariana Santos, Daniel Sganzerla, Caroline Cabral Robinson, Denise de Souza, Renata Kochhann, Maicon Falavigna, Luis Azevedo, Fernando Bozza, Tarek Sharshar, Regis Goulart Rosa, Cristina Granja and Cassiano Teixeira
    Citation: Annals of Intensive Care 2024 14:116
    Content type: Research Published on:

  34. In this review, we aimed to comprehensively summarize current literature on pathophysiology, relevance, diagnosis and treatment of fluid accumulation in patients with sepsis/septic shock. Fluid accumulation sy...

    Authors: Carmen Andrea Pfortmueller, Wojciech Dabrowski, Rob Wise, Niels van Regenmortel and Manu L. N. G. Malbrain
    Citation: Annals of Intensive Care 2024 14:115
    Content type: Review Published on:

  36. Severe acute respiratory infections, such as community-acquired pneumonia, hospital-acquired pneumonia, and ventilator-associated pneumonia, constitute frequent and lethal pulmonary infections in the intensive...

    Authors: Pedro Póvoa, Luís Coelho, José Pedro Cidade, Adrian Ceccato, Andrew Conway Morris, Jorge Salluh, Vandack Nobre, Saad Nseir, Ignacio Martin-Loeches, Thiago Lisboa, Paula Ramirez, Anahita Rouzé, Daniel A. Sweeney and Andre C. Kalil
    Citation: Annals of Intensive Care 2024 14:113
    Content type: Review Published on:

  38. In sepsis, initial resuscitation with fluids is followed by efforts to achieve a negative fluid balance. However, patients with sepsis-associated acute kidney injury (SA-AKI) often need diuretic or renal repla...

    Authors: Lars Palmowski, Simone Lindau, Laura Contreras Henk, Britta Marko, Andrea Witowski, Hartmuth Nowak, Sandra E. Stoll, Kai Zacharowski, Bernd W. Böttiger, Jürgen Peters, Michael Adamzik, Fabian Dusse and Tim Rahmel
    Citation: Annals of Intensive Care 2024 14:111
    Content type: Research Published on:

  39. Although the present diagnosis of acute kidney injury (AKI) involves measurement of acute increases in serum creatinine (SC) and reduced urine output (UO), measurement of UO is underutilized for diagnosis of A...

    Authors: Manu L. N. G. Malbrain, Krista Tantakoun, Anthony T. Zara, Nicole C. Ferko, Timothy Kelly and Wojciech Dabrowski
    Citation: Annals of Intensive Care 2024 14:110
    Content type: Review Published on:

  40. Post-intensive care syndrome (PICS), defined as physical, cognitive, and mental-health symptoms persisting long after intensive-care-unit (ICU) discharge, is increasingly recognised as a healthcare priority. D...

    Authors: Maïté Agbakou, Margot Combet, Maëlle Martin, Gauthier Blonz, Luc Desmedt, Amélie Seguin, Jérémie Lemarié, Olivier Zambon, Jean Reignier, Jean-Baptiste Lascarrou, Stephan Ehrmann and Emmanuel Canet
    Citation: Annals of Intensive Care 2024 14:109
    Content type: Research Published on:

  41. Dynamic arterial elastance (Eadyn) has been investigated for its ability to predict hypotension during the weaning of vasopressors. Our study focused on assessing Eadyn’s performance in the context of critically ...

    Authors: Jorge Iván Alvarado-Sánchez, Sergio Salazar-Ruiz, Juan Daniel Caicedo-Ruiz, Juan José Diaztagle-Fernández, Yenny Rocio Cárdenas-Bolivar, Fredy Leonardo Carreño-Hernandez, Andrés Felipe Mora-Salamanca, Andrea Valentina Montañez-Nariño, María Valentina Stozitzky-Ríos, Carlos Santacruz-Herrera, Gustavo Adolfo Ospina-Tascón and Michael R. Pinsky
    Citation: Annals of Intensive Care 2024 14:108
    Content type: Review Published on:

  42. Adults in the intensive care unit (ICU) commonly experience distressing symptoms and other concerns such as pain, delirium, and breathlessness. Breathlessness management is not supported by any ICU guidelines,...

    Authors: Ben R. Richardson, Maxens Decavèle, Alexandre Demoule, Fliss E. M. Murtagh and Miriam J. Johnson
    Citation: Annals of Intensive Care 2024 14:107
    Content type: Review Published on:

  43. The recruitment-to-inflation ratio (R/I) has been recently proposed to bedside assess response to PEEP. The impact of PEEP on ventilator-induced lung injury depends on the extent of dynamic strain reduction. W...

    Authors: Francesco Murgolo, Domenico L. Grieco, Savino Spadaro, Nicola Bartolomeo, Rossella di Mussi, Luigi Pisani, Marco Fiorentino, Alberto Maria Crovace, Luca Lacitignola, Francesco Staffieri and Salvatore Grasso
    Citation: Annals of Intensive Care 2024 14:106
    Content type: Research Published on:

  45. Patients on veno-arterial extracorporeal membrane oxygenation (V-A ECMO) support are at a high risk of hemorrhagic complications, including upper gastrointestinal bleeding (UGIB). The objective of this study w...

    Authors: Quentin de Roux, Yekcan Disli, Wulfran Bougouin, Marie Renaudier, Ali Jendoubi, Jean-Claude Merle, Mathilde Delage, Lucile Picard, Faiza Sayagh, Chamsedine Cherait, Thierry Folliguet, Christophe Quesnel, Aymeric Becq and Nicolas Mongardon
    Citation: Annals of Intensive Care 2024 14:104
    Content type: Research Published on:

  46. Patients with advanced critical illness often receive more intensive treatment than they would choose for themselves, which contributes to high health care costs near the end of life. The purpose of this study...

    Authors: Sarah K. Andersen, Chung-Chou H. Chang, Robert M. Arnold, Caroline Pidro, Joseph M. Darby, Derek C. Angus and Douglas B. White
    Citation: Annals of Intensive Care 2024 14:103
    Content type: Research Published on:

  48. A notable increase in severe cases of COVID-19, with significant hospitalizations due to the emergence and spread of JN.1 was observed worldwide in late 2023 and early 2024. However, no clinical data are avail...

    Authors: Nicolas de Prost, Etienne Audureau, Antoine Guillon, Lynda Handala, Sébastien Préau, Aurélie Guigon, Fabrice Uhel, Quentin Le Hingrat, Flora Delamaire, Claire Grolhier, Fabienne Tamion, Alice Moisan, Cédric Darreau, Jean Thomin, Damien Contou, Amandine Henry…
    Citation: Annals of Intensive Care 2024 14:101
    Content type: Research Published on:

  49. Previous retrospective research has shown that maintaining prone positioning (PP) for an average of 40 h is associated with an increase of survival rates in intubated patients with COVID-19-related acute respi...

    Authors: Christophe Le Terrier, Thaïs Walter, Said Lebbah, David Hajage, Florian Sigaud, Claude Guérin, Luc Desmedt, Steve Primmaz, Vincent Joussellin, Chiara Della Badia, Jean-Damien Ricard, Jérôme Pugin and Nicolas Terzi
    Citation: Annals of Intensive Care 2024 14:100
    Content type: Research Published on:

    The Correction to this article has been published in Annals of Intensive Care 2024 14:142

  50. EEG reactivity is a predictor for neurological outcome in comatose patients after cardiac arrest (CA); however, its application is limited by variability in stimulus types and visual assessment. We aimed to ev...

    Authors: Gang Liu, Yuan Wang, Fei Tian, Weibi Chen, Lili Cui, Mengdi Jiang, Yan Zhang, Keming Gao, Yingying Su and Hongxing Wang
    Citation: Annals of Intensive Care 2024 14:99
    Content type: Research Published on:
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  • Citation Impact 2023
    Journal Impact Factor: 5.7
    5-year Journal Impact Factor: 6.0
    Source Normalized Impact per Paper (SNIP): 1.749
    SCImago Journal Rank (SJR): 2.061

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    Submission to first editorial decision (median days): 7
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  • ISSN: 2110-5820 (electronic)