Elevated production of radical oxygen species by polymorphonuclear neutrophils in cerebrospinal fluid infection

Annals of Intensive Care

Table 1 Clinical and biological variables, separated by CSF inflammation and infection status

	Negative n = 8	Noninfected n = 15	Infected n = 7	P value	P1	P2	P3
Temperature°C	39.0(38.5-39.3)	39.4(39.0-39.8)	39.5(38-40.3)	0.4557
Blood leukocytes10⁹/mm³	13.4(10.3-18)	12.5(10.1-16.2)	19.1(12.5-21.1)	0.9158		0.0039
Blood glucosemmol/L	6.5(5.4-7.3)	6.9(6.4-7.6)	8(7.1-8.5)	0.2496
Delaydays	5(4-7)	7(5-10)	11(10-18)	0.0027	0.049	0.0026	0.0165
CSF leukocytes/mm³	32(6-73)	360(170-1022)	460(190-1090)	0.0002	0.0001	0.0012
CSF % PMN	83(65-89)	83(74-93)	88(83-93)	0.6663
CSF glucosemmol/L	3.6(3.0-3.9)	3.7(3.3-4.4)	2(0.9-3.9)	0.3013
CSF proteinsg/L	0.7(0.5-0.7)	0.6(0.4-0.8)	1.5(1.1-2.3)	0.0042		0.0039	0.0045

P value comparison among the three groups (Kruskall-Wallis). Between-group comparison: P1 value negative versus noninfected, P2 value negative versus infected, P3 value noninfected versus infected groups (Mann-Whitney test). Data are expressed as median (interquartile range)