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  1. Authors: Charles-Hervé Vacheron, Anne Kaas, Jean-Philippe Rasigade, Frederic Aubrun, Laurent Argaud, Baptiste Balanca, Jean-Luc Fellahi, Jean Christophe Richard, Anne-Claire Lukaszewicz, Florent Wallet, Olivier Dauwalder and Arnaud Friggeri
    Citation: Annals of Intensive Care 2024 14:81

    The original article was published in Annals of Intensive Care 2024 14:73

  2. The renin-angiotensin system (RAS) constitutes one of the principal mechanisms to maintain hemodynamic and fluid homeostasis. However, most research until now on RAS primarily focuses on its relationship with ...

    Authors: Yuki Kotani, Mark Chappell, Giovanni Landoni, Alexander Zarbock, Rinaldo Bellomo and Ashish K. Khanna
    Citation: Annals of Intensive Care 2024 14:79
  3. Reverse triggering (RT) was described in 2013 as a form of patient-ventilator asynchrony, where patient’s respiratory effort follows mechanical insufflation. Diagnosis requires esophageal pressure (Pes) or diaphr...

    Authors: Robert Jackson, Audery Kim, Nikolay Moroz, L. Felipe Damiani, Domenico Luca Grieco, Thomas Piraino, Jan O. Friedrich, Alain Mercat, Irene Telias and Laurent J. Brochard
    Citation: Annals of Intensive Care 2024 14:78
  4. To identify key components and variations in family-centered care practices.

    Authors: Élie Azoulay, Nancy Kentish-Barnes, Carole Boulanger, Giovanni Mistraletti, Margo van Mol, Gabriel Heras-La Calle, Elisa Estenssoro, Peter Vernon van Heerden, Maria-Cruz Martin Delgado, Anders Perner, Yaseen M Arabi, Sheila Nainan Myatra, Jon Henrik Laake, Jan J. De Waele, Michael Darmon and Maurizio Cecconi
    Citation: Annals of Intensive Care 2024 14:77
  5. A 10-day dexamethasone regimen has emerged as the internationally adopted standard-of-care for severe COVID-19 patients. However, the immune response triggered by SARS-CoV-2 infection remains a complex and dyn...

    Authors: Guillaume Monneret, Nicolas Voirin, Jean-Christophe Richard, Martin Cour, Thomas Rimmelé, Lorna Garnier, Hodane Yonis, Remy Coudereau, Morgane Gossez, Christophe Malcus, Florent Wallet, Marie-Charlotte Delignette, Frederic Dailler, Marielle Buisson, Laurent Argaud, Anne-Claire Lukaszewicz…
    Citation: Annals of Intensive Care 2024 14:76
  6. Current data on post-discharge mortality and rehospitalization is still insufficient among in-hospital survivors of cardiogenic shock (CS), including acute myocardial infarction (AMI) and non-AMI survivors.

    Authors: Shih-Chieh Chien, Cheng-An Wang, Hung-Yi Liu, Chao-Feng Lin, Chun-Yao Huang and Li-Nien Chien
    Citation: Annals of Intensive Care 2024 14:74
  7. The efficacy and safety of cefiderocol in ICU patients with difficult-to-treat resistance (DTR) non-fermenting Gram-negative bacteria (Nf-GNB) are not as well-established. Consequently, we conducted a cohort s...

    Authors: Charles-Hervé Vacheron, Anne Kaas, Jean-Philippe Rasigade, Frederic Aubrun, Laurent Argaud, Baptiste Balanca, Jean-Luc Fellahi, Jean Christophe Richard, Anne-Claire Lukaszewicz, Florent Wallet, Olivier Dauwalder and Arnaud Friggeri
    Citation: Annals of Intensive Care 2024 14:73

    The Correction to this article has been published in Annals of Intensive Care 2024 14:81

  8. COVID-19-associated pulmonary fibrosis remains frequent. This study aimed to investigate pulmonary redox balance in COVID-19 ARDS patients and possible relationship with pulmonary fibrosis and long-term lung a...

    Authors: Chun Yang, Yuanyuan Tan, Zihao Li, Lei Hu, Yuanyuan Chen, Shouliang Zhu, Jiawei Hu, Tingting Huai, Mingqing Li, Guobin Zhang, Dewang Rao, Guanghe Fei, Min Shao and Zhenxing Ding
    Citation: Annals of Intensive Care 2024 14:72
  9. Very old critically ill patients pose a growing challenge for intensive care. Critical illness and the burden of treatment in the intensive care unit (ICU) can lead to a long-lasting decline of functional and ...

    Authors: Jeremy M. Jacobs, Ana Rahamim, Michael Beil, Bertrand Guidet, Helene Vallet, Hans Flaatten, Susannah K. Leaver, Dylan de Lange, Wojciech Szczeklik, Christian Jung and Sigal Sviri
    Citation: Annals of Intensive Care 2024 14:71
  10. Hospital-acquired bloodstream infections are common in the intensive care unit (ICU) and have a high mortality rate. Patients with cirrhosis are especially susceptible to infections, yet there is a knowledge g...

    Authors: Hannah Wozniak, Alexis Tabah, François Barbier, Stéphane Ruckly, Ambre Loiodice, Murat Akova, Marc Leone, Andrew Conway Morris, Matteo Bassetti, Kostoula Arvaniti, Ricard Ferrer, Liesbet de Bus, Jose Artur Paiva, Hendrik Bracht, Adam Mikstacki, Adel Alsisi…
    Citation: Annals of Intensive Care 2024 14:70
  11. Alongside the recent worldwide expansion of hypervirulent Klebsiella pneumoniae (KP) infections, the available literature regarding cases of community acquired pneumonias (KP-CAP) remains scarce but reports a str...

    Authors: Vincent Grosjean, Simon B. Gressens, Tài Pham, Stéphane Gaudry, Hafid Ait-Oufella, Nicolas De Prost, Julien Mayaux, Emmanuel Guerot, Véronique Leflon-Guibout, Noémie Mayer, Frédéric Bert, Nathalie Gault, Clément R. Massonnaud and Damien Roux
    Citation: Annals of Intensive Care 2024 14:69
  12. It remains unclear whether conservative oxygen therapy (COT) or liberal oxygen therapy (LOT) is more beneficial to the clinical outcomes of intensive care unit (ICU) patients. We systematically reviewed the ef...

    Authors: Xin-yu Li, Bing Dai, Hai-jia Hou, Hong-wen Zhao, Wei Wang, Jian Kang and Wei Tan
    Citation: Annals of Intensive Care 2024 14:68
  13. To describe ventilator-associated pneumonia (VAP) recurrence in COVID-19 patients requiring extracorporeal membrane oxygenation (ECMO) support, and to evaluate the impact of antimicrobial treatment duration of...

    Authors: Elena Collado-Lledó, Quentin Moyon, Juliette Chommeloux, Marc Pineton de Chambrun, Guillaume Hékimian, Ouriel Saura, David Lévy, Matthieu Schmidt, Alain Combes, Charles-Edouard Luyt and Lucie Le Fevre
    Citation: Annals of Intensive Care 2024 14:67
  14. Multiple randomized controlled studies have compared numerous antibiotic regimens, including new, recently commercialized antibiotics in the treatment of nosocomial pneumonia (NP). The objective of this Bayesi...

    Authors: David Luque Paz, Dara Chean, Pierre Tattevin, Damien Luque Paz, Betsega Assefa Bayeh, Achille Kouatchet, Delphine Douillet and Jérémie Riou
    Citation: Annals of Intensive Care 2024 14:66
  15. During the first COVID-19 pandemic wave, COVID-19-associated pulmonary aspergillosis (CAPA) has been reported in up to 11–28% of critically ill COVID-19 patients and associated with increased mortality. As new...

    Authors: Pierre Bay, Etienne Audureau, Sébastien Préau, Raphaël Favory, Aurélie Guigon, Nicholas Heming, Elyanne Gault, Tài Pham, Amal Chaghouri, Matthieu Turpin, Laurence Morand-Joubert, Sébastien Jochmans, Aurélia Pitsch, Sylvie Meireles, Damien Contou, Amandine Henry…
    Citation: Annals of Intensive Care 2024 14:65
  16. Maintaining tissue perfusion in sepsis depends on vascular integrity provided by the endothelial glycocalyx, the critical layer covering the luminal surface of blood vessels. The glycocalyx is composed of prot...

    Authors: Toshiaki Iba, Cheryl L. Maier, Julie Helms, Ricard Ferrer, Jecko Thachil and Jerrold H. Levy
    Citation: Annals of Intensive Care 2024 14:64
  17. Weaning from invasive mechanical ventilation (MV) is a complex and challenging process that involves multiple pathophysiological mechanisms. A combined ultrasound evaluation of the heart, lungs, and diaphragm ...

    Authors: Jia Song, Qiancheng Luo, Xinle Lai, Weihang Hu, Yihua Yu, Minjia Wang, Kai Yang, Gongze Chen, Wenwei Chen, Qian Li, Caibao Hu and Shijin Gong
    Citation: Annals of Intensive Care 2024 14:60
  18. The aim of this study is to assess whether a strategy combining spontaneous breathing trial (SBT) with both pressure support (PS) and positive end-expiratory pressure (PEEP) and extended use of post-extubation...

    Authors: Mehdi Mezidi, Hodane Yonis, Louis Chauvelot, Guillaume Deniel, François Dhelft, Maxime Gaillet, Ines Noirot, Laure Folliet, Paul Chabert, Guillaume David, William Danjou, Loredana Baboi, Clotilde Bettinger, Pauline Bernon, Mehdi Girard, Judith Provoost…
    Citation: Annals of Intensive Care 2024 14:59
  19. This article describes the structures and processes involved in healthcare delivery for sepsis, from the prehospital setting until rehabilitation. Quality improvement initiatives in sepsis may reduce both morb...

    Authors: Romain Jouffroy, Félix Djossou, Rémi Neviere, Samir Jaber, Benoît Vivien, Nicholas Heming and Papa Gueye
    Citation: Annals of Intensive Care 2024 14:58
  20. Plasmapheresis is widely used for severe hypertriglyceridemia-associated acute pancreatitis (HTG-AP) to remove excessive triglycerides from plasma. This study aimed to evaluate whether plasmapheresis could imp...

    Authors: Lanting Wang, Jing Zhou, Cheng Lv, Donghuang Hong, Zuozheng Wang, Wenjian Mao, Yuxiu Liu, Zixiong Zhang, Yuanzhen Li, Gang Li, Bo Ye, Baiqiang Li, Longxiang Cao, Zhihui Tong, Weiqin Li and Lu Ke
    Citation: Annals of Intensive Care 2024 14:57
  21. Hyperoxemia is common and associated with poor outcome during veno-arterial extracorporeal membrane oxygenation (VA ECMO) support for cardiogenic shock. However, little is known about practical daily managemen...

    Authors: Hadrien Winiszewski, Thibault Vieille, Pierre-Grégoire Guinot, Nicolas Nesseler, Mael Le Berre, Laure Crognier, Anne-Claude Roche, Jean-Luc Fellahi, Nicolas D’Ostrevy, Zied Ltaief, Juliette Didier, Osama Abou Arab, Simon Meslin, Vincent Scherrer, Guillaume Besch, Alexandra Monnier…
    Citation: Annals of Intensive Care 2024 14:56
  22. Sickle cell disease (SCD) is one of the most frequent inherited diseases in the world. Over the last decades, in high-income countries, an important decrease in mortality have been observed due to the improvem...

    Authors: Michaël Levy, Jérôme Naudin, Guillaume Geslain, Arielle Maroni, Bérengère Koehl, Fleur Le Bourgeois, Géraldine Poncelet, Maryline Chomton, Anna Deho, Sébastien Julliand, Stéphane Dauger and Julie Sommet
    Citation: Annals of Intensive Care 2024 14:55
  23. The influence of socioeconomic deprivation on health inequalities is established, but its effect on critically ill patients remains unclear, due to inconsistent definitions in previous studies.

    Authors: Morgan Benaïs, Matthieu Duprey, Laura Federici, Michel Arnaout, Pierre Mora, Marc Amouretti, Irma Bourgeon-Ghittori, Stéphane Gaudry, Pierre Garçon, Danielle Reuter, Guillaume Geri, Bruno Megarbane, Jordane Lebut, Armand Mekontso-Dessap, Jean-Damien Ricard, Daniel da Silva…
    Citation: Annals of Intensive Care 2024 14:54
  24. Left atrial strain (LAS) is a measure of atrial wall deformation during cardiac cycle and reflects atrial contribution to cardiovascular performance. Pathophysiological significance of LAS in critically ill pa...

    Authors: Marta Cicetti, François Bagate, Cristina Lapenta, Ségolène Gendreau, Paul Masi and Armand Mekontso Dessap
    Citation: Annals of Intensive Care 2024 14:53
  25. Fluid accumulation (FA) is known to be associated with acute kidney injury (AKI) during intensive care unit (ICU) stay but data on mid-term renal outcome is scarce. The aim of this study was to investigate the...

    Authors: Debora M. Hofer, Livio Ruzzante, Jan Waskowski, Anna S. Messmer and Carmen A. Pfortmueller
    Citation: Annals of Intensive Care 2024 14:52
  26. Legionnaires’ disease (LD) is a common but under-diagnosed cause of community-acquired pneumonia (CAP), although rapid detection of urine antigen testing (UAT) and advances in molecular testing have improved t...

    Authors: Jordi Rello, Camille Allam, Alfonsina Ruiz-Spinelli and Sophie Jarraud
    Citation: Annals of Intensive Care 2024 14:51
  27. Several studies have validated capillary refill time (CRT) as a marker of tissue hypoperfusion, and recent guidelines recommend CRT monitoring during septic shock resuscitation. Therefore, it is relevant to fu...

    Authors: Glenn Hernández, Emilio Daniel Valenzuela, Eduardo Kattan, Ricardo Castro, Camila Guzmán, Alicia Elzo Kraemer, Nicolás Sarzosa, Leyla Alegría, Roberto Contreras, Vanessa Oviedo, Sebastián Bravo, Dagoberto Soto, Claudia Sáez, Hafid Ait-Oufella, Gustavo Ospina-Tascón and Jan Bakker
    Citation: Annals of Intensive Care 2024 14:49
  28. Premorbid conditions influence the outcome of acutely ill adult patients aged 80 years and over who are admitted to the ICU. The aim of this study was to determine the influence of such premorbid conditions on...

    Authors: Dylan W. de Lange, Ivo W. Soliman, Susannah Leaver, Ariane Boumendil, Lenneke E. M. Haas, Ximena Watson, Carol Boulanger, Wojciech Szczeklik, Antonio Artigas, Alessandro Morandi, Finn Andersen, Christian Jung, Rui Moreno, Sten Walther, Sandra Oeyen, Joerg C. Schefold…
    Citation: Annals of Intensive Care 2024 14:46
  29. Cardiogenic shock (CS) is characterized by low cardiac output and sustained tissue hypoperfusion that may result in end-organ dysfunction and death. CS is associated with high short-term mortality, and its man...

    Authors: Driss Laghlam, Sarah Benghanem, Sofia Ortuno, Nadia Bouabdallaoui, Stephane Manzo-Silberman, Olfa Hamzaoui and Nadia Aissaoui
    Citation: Annals of Intensive Care 2024 14:45
  30. Due to aging population and increasing part of immunocompromised patients, a raise in life-threatening organ damage related to VZV can be expected. Two retrospective studies were already conducted on VZV in IC...

    Authors: Jolan Malherbe, Pierre Godard, Jean-Claude Lacherade, Valentin Coirier, Laurent Argaud, Hervé Hyvernat, Francis Schneider, Julien Charpentier, Florent Wallet, Juliette Pocquet, Gaëtan Plantefeve, Jean-Pierre Quenot, Pierre Bay, Agathe Delbove, Hugues Georges, Tomas Urbina…
    Citation: Annals of Intensive Care 2024 14:44
  31. Reliable predictors of outcomes in venoarterial extracorporeal membrane oxygenation (VA-ECMO) therapy are limited. While elevated lactate levels over time have been linked to outcomes in cardiogenic shock (CS)...

    Authors: Bruno Levy, Nicolas Girerd, Guillaume Baudry, Kevin Duarte, Samuel Cuau, Jan Bakker and Antoine Kimmoun
    Citation: Annals of Intensive Care 2024 14:43
  32. Impaired intestinal barrier function can enable passage of enteric microorganisms into the bloodstream and lead to nosocomial bloodstream infections during critical illness. We aimed to determine the relative ...

    Authors: Meri R. J. Varkila, Diana M. Verboom, Lennie P. G. Derde, Tom van der Poll, Marc J. M. Bonten and Olaf L. Cremer
    Citation: Annals of Intensive Care 2024 14:42
  33. This study aimed to assess a potential organ protective effect of volatile sedation in a scenario of severe inflammation with an early cytokine storm (in particular IL-6 elevation) in patients suffering from C...

    Authors: Beatrice Beck-Schimmer, Erik Schadde, Urs Pietsch, Miodrag Filipovic, Seraina Dübendorfer-Dalbert, Patricia Fodor, Tobias Hübner, Reto Schuepbach, Peter Steiger, Sascha David, Bernard D. Krüger, Thomas A. Neff and Martin Schläpfer
    Citation: Annals of Intensive Care 2024 14:41
  34. Coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS) is associated with high mortality. Extracorporeal membrane oxygenation (ECMO) has been proposed in this setting, but optim...

    Authors: Matthieu Petit, Misylias Bouaoud, Edouard Jullien, Adrien Joseph, Bruno Evrard, Cyril Charron, Anousone Daulasim, Annick Legras, Maeva Gourraud, Marine Goudelin, Philippe Vignon and Antoine Vieillard-Baron
    Citation: Annals of Intensive Care 2024 14:40
  35. The incidence, causes and impact of diaphragm thickness evolution in veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock are unknown.

    Authors: Pierre-Henri Moury, Alexandre Béhouche, Sébastien Bailly, Zoé Durand, Géraldine Dessertaine, Angelina Pollet, Samir Jaber, Samuel Verges and Pierre Albaladejo
    Citation: Annals of Intensive Care 2024 14:38
  36. Bloodstream infections (BSIs) by Gram-negative pathogens play a major role in intensive care patients, both in terms of prevalence and severity, especially if multi-drug resistant pathogens are involved. Early...

    Authors: Matteo Rinaldi, Milo Gatti, Tommaso Tonetti, Domenico Nocera, Simone Ambretti, Andrea Berlingeri, Giacomo Nigrisoli, Elisabetta Pierucci, Antonio Siniscalchi, Federico Pea, Pierluigi Viale and Maddalena Giannella
    Citation: Annals of Intensive Care 2024 14:36
  37. In some cases of patients with out-of-hospital cardiac arrest (OHCA) who underwent extracorporeal cardiopulmonary resuscitation (ECPR), negative pupillary light reflex (PLR) and mydriasis upon hospital arrival...

    Authors: Takuro Hamaguchi, Toru Takiguchi, Tomohisa Seki, Naoki Tominaga, Jun Nakata, Takeshi Yamamoto, Takashi Tagami, Akihiko Inoue, Toru Hifumi, Tetsuya Sakamoto, Yasuhiro Kuroda, Shoji Yokobori and the SAVE-J II study group
    Citation: Annals of Intensive Care 2024 14:35
  38. Ventilator-associated pneumonia (VAP) is the leading nosocomial infection in critical care and is associated with adverse outcomes. When VAP is suspected, starting antibiotic therapy (AT) immediately after pul...

    Authors: Maëlle Martin, Solène Forveille, Jean-Baptiste Lascarrou, Amélie Seguin, Emmanuel Canet, Jérémie Lemarié, Maïté Agbakou, Luc Desmedt, Gauthier Blonz, Olivier Zambon, Stéphane Corvec, Aurélie Le Thuaut and Jean Reignier
    Citation: Annals of Intensive Care 2024 14:33

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