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  1. Preliminary reports have described significant procoagulant events in patients with coronavirus disease-2019 (COVID-19), including life-threatening pulmonary embolism (PE).

    Authors: Yasser Sakr, Manuela Giovini, Marc Leone, Giacinto Pizzilli, Andreas Kortgen, Michael Bauer, Tommaso Tonetti, Gary Duclos, Laurent Zieleskiewicz, Samuel Buschbeck, V. Marco Ranieri and Elio Antonucci

    Citation: Annals of Intensive Care 2020 10:124

    Content type: Review

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  2. Acute respiratory failure is the main reason for admission to the intensive care unit (ICU) in HIV-infected adults. There is little data about the epidemiology of respiratory viruses in this population.

    Authors: Alexandre Elabbadi, Jérémie Pichon, Benoit Visseaux, Aurélie Schnuriger, Lila Bouadma, Quentin Philippot, Juliette Patrier, Vincent Labbé, Stéphane Ruckly, Muriel Fartoukh, Jean-François Timsit and Guillaume Voiriot

    Citation: Annals of Intensive Care 2020 10:123

    Content type: Research

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  3. Multiple screening Duplex ultrasound scans (DUS) are performed in trauma patients at high risk of deep vein thrombosis (DVT) in the intensive care unit (ICU). Intensive care physician performed compression ult...

    Authors: Lloyd Roberts, Tom Rozen, Deirdre Murphy, Adam Lawler, Mark Fitzgerald, Harry Gibbs, Kyle Brooks, Joshua F. Ihle, Tim Leong, Judit Orosz, Eldho Paul and Vinodh Bhagyalakshmi Nanjayya

    Citation: Annals of Intensive Care 2020 10:122

    Content type: Research

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  4. Persistent hypotension is a frequent complication after cardiac surgery with cardiopulmonary bypass (CPB). Midodrine, an orally administered alpha agonist, could potentially reduce intravenous vasopressor use ...

    Authors: Jan-Alexis Tremblay, Philippe Laramée, Yoan Lamarche, André Denault, William Beaubien-Souligny, Anne-Julie Frenette, Loay Kontar, Karim Serri and Emmanuel Charbonney

    Citation: Annals of Intensive Care 2020 10:121

    Content type: Research

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  5. Although mechanical ventilation is a lifesaving treatment, abundant evidence indicates that its prolonged use (1 week or more) promotes respiratory muscle weakness due to both contractile dysfunction and atrop...

    Authors: Paolo Formenti, Michele Umbrello, Martin Dres and Davide Chiumello

    Citation: Annals of Intensive Care 2020 10:120

    Content type: Review

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  6. Data on the prevalence of bacterial and viral co-infections among patients admitted to the ICU for acute respiratory failure related to SARS-CoV-2 pneumonia are lacking. We aimed to assess the rate of bacteria...

    Authors: Damien Contou, Aurore Claudinon, Olivier Pajot, Maïté Micaëlo, Pascale Longuet Flandre, Marie Dubert, Radj Cally, Elsa Logre, Megan Fraissé, Hervé Mentec and Gaëtan Plantefève

    Citation: Annals of Intensive Care 2020 10:119

    Content type: Research

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  7. The French Society of Intensive Care Medicine (SRLF), jointly with the French-Speaking Group of Paediatric Emergency Rooms and Intensive Care Units (GFRUP) and the French-Speaking Association of Paediatric Sur...

    Authors: Jean-François Timsit, Julien Baleine, Louis Bernard, Silvia Calvino-Gunther, Michael Darmon, Jean Dellamonica, Eric Desruennes, Marc Leone, Alain Lepape, Olivier Leroy, Jean-Christophe Lucet, Zied Merchaoui, Olivier Mimoz, Benoit Misset, Jean-Jacques Parienti, Jean-Pierre Quenot…

    Citation: Annals of Intensive Care 2020 10:118

    Content type: Review

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  8. Acute Kidney Injury (AKI) is a frequent complication of severe SARS-CoV-2 infection. Multiple mechanisms are involved in COVID-19-associated AKI, from direct viral infection and secondary inflammation to compl...

    Authors: Adrien Joseph, Lara Zafrani, Asma Mabrouki, Elie Azoulay and Michael Darmon

    Citation: Annals of Intensive Care 2020 10:117

    Content type: Research

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  9. Nonintubated chest trauma patients with fractured ribs admitted to the intensive care unit (ICU) are at risk for complications and may require invasive ventilation at some point. Effective pain control is esse...

    Authors: Konstantinos Bachoumas, Albrice Levrat, Aurélie Le Thuaut, Stéphane Rouleau, Samuel Groyer, Hervé Dupont, Paul Rooze, Nathanael Eisenmann, Timothée Trampont, Julien Bohé, Benjamin Rieu, Jean-Charles Chakarian, Aurélie Godard, Laura Frederici, Stephanie Gélinotte, Aurélie Joret…

    Citation: Annals of Intensive Care 2020 10:116

    Content type: Research

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  10. Critical illness has detrimental effects on the diaphragm, but the impact of critical illness on other major muscles of the respiratory pump has been largely neglected. This study aimed to determine the impact...

    Authors: Marloes M. IJland, Joris Lemson, Johannes G. van der Hoeven and Leo M. A. Heunks

    Citation: Annals of Intensive Care 2020 10:115

    Content type: Research

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  11. Capillary refill time (CRT) may improve more rapidly than lactate in response to increments in systemic flow. Therefore, it can be assessed more frequently during septic shock (SS) resuscitation. Hyperlactatem...

    Authors: Eduardo Kattan, Glenn Hernández, Gustavo Ospina-Tascón, Emilio Daniel Valenzuela, Jan Bakker and Ricardo Castro

    Citation: Annals of Intensive Care 2020 10:114

    Content type: Research

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  12. The objective of this study was to evaluate the ability of endothelial biomarkers to early predict clinical deterioration of patients admitted to the emergency department (ED) with a suspected sepsis. This was...

    Authors: Thomas Lafon, Marie-Angélique Cazalis, Christine Vallejo, Karim Tazarourte, Sophie Blein, Alexandre Pachot, Pierre-François Laterre, Said Laribi and Bruno François

    Citation: Annals of Intensive Care 2020 10:113

    Content type: Research

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  13. Gasping during cardiac arrest is associated with favourable neurological outcomes for out-of-hospital cardiac arrest. Moreover, while extracorporeal cardiopulmonary resuscitation (ECPR) performed for refractor...

    Authors: Naofumi Bunya, Hirofumi Ohnishi, Kenshiro Wada, Ryuichiro Kakizaki, Takehiko Kasai, Nobutaka Nagano, Nobuaki Kokubu, Kei Miyata, Shuji Uemura, Keisuke Harada and Eichi Narimatsu

    Citation: Annals of Intensive Care 2020 10:112

    Content type: Research

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  14. Red blood cell (RBC) transfusions are associated with risks including immunological reactions and volume overload. Current guidelines suggest a restrictive transfusion strategy in most patients with sepsis but...

    Authors: Caroline Ulfsdotter Nilsson, Peter Bentzer, Linnéa E. Andersson, Sofia A. Björkman, Fredrik P. Hanssson and Thomas Kander

    Citation: Annals of Intensive Care 2020 10:111

    Content type: Research

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  15. The COVID-19 pandemic has resulted in an unprecedented healthcare crisis with a high prevalence of psychological distress in healthcare providers. We sought to document the prevalence of burnout syndrome among...

    Authors: Elie Azoulay, Jan De Waele, Ricard Ferrer, Thomas Staudinger, Marta Borkowska, Pedro Povoa, Katerina Iliopoulou, Antonio Artigas, Stefan J. Schaller, Manu Shankar Hari, Mariangela Pellegrini, Michael Darmon, Jozef Kesecioglu and Maurizio Cecconi

    Citation: Annals of Intensive Care 2020 10:110

    Content type: Research

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  16. Hypoxemia is the main feature of COVID-19-related acute respiratory distress syndrome (C-ARDS), but its underlying mechanisms are debated, especially in patients with low respiratory system elastance (Ers). We...

    Authors: Paul Masi, François Bagate, Thomas d’Humières, Lara Al-Assaad, Laure Abou Chakra, Genevieve Derumeaux and Armand Mekontso Dessap

    Citation: Annals of Intensive Care 2020 10:108

    Content type: Letter to the Editor

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  17. Protective mechanical ventilation (MV) aims at limiting global lung deformation and has been associated with better clinical outcomes in acute respiratory distress syndrome (ARDS) patients. In ARDS lungs witho...

    Authors: Daniel E. Hurtado, Benjamín Erranz, Felipe Lillo, Mauricio Sarabia-Vallejos, Pablo Iturrieta, Felipe Morales, Katherine Blaha, Tania Medina, Franco Diaz and Pablo Cruces

    Citation: Annals of Intensive Care 2020 10:107

    Content type: Research

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  18. In critically ill patients, tigecycline (TGC) remains an important therapeutic option due to its efficacy against multiresistant Gram-positive and Gram-negative bacteria. TGC is metabolized and eliminated pred...

    Authors: Rawan Alraish, Sebastian G. Wicha, Otto R. Frey, Anka C. Roehr, Johann Pratschke, Martin Stockmann, Tilo Wuensch and Magnus Kaffarnik

    Citation: Annals of Intensive Care 2020 10:106

    Content type: Research

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  19. Delirium is common in intensive care patients and is associated with short- and long-term adverse outcomes. We investigated the long-term risk of cognitive impairment and post-traumatic stress disorder (PTSD) ...

    Authors: Daniella Bulic, Michael Bennett, Ekavi N. Georgousopoulou, Yahya Shehabi, Tai Pham, Jeffrey C. L. Looi and Frank M. P. van Haren

    Citation: Annals of Intensive Care 2020 10:104

    Content type: Research

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  20. Differentiating Ventilator-Associated Tracheobronchitis (VAT) from Ventilator-Associated Pneumonia (VAP) may be challenging for clinicians, yet their management currently differs. In this study, we evaluated t...

    Authors: Alexandre Gaudet, Ignacio Martin-Loeches, Pedro Povoa, Alejandro Rodriguez, Jorge Salluh, Alain Duhamel and Saad Nseir

    Citation: Annals of Intensive Care 2020 10:101

    Content type: Research

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  21. Since December 2019, an outbreak of Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) initially emerged in Wuhan, China, and has spread worldwide no...

    Authors: Jiao Liu, Sheng Zhang, Zhixiong Wu, You Shang, Xuan Dong, Guang Li, Lidi Zhang, Yizhu Chen, Xiaofei Ye, Hangxiang Du, Yongan Liu, Tao Wang, SiSi Huang, Limin Chen, Zhenliang Wen, Jieming Qu…

    Citation: Annals of Intensive Care 2020 10:99

    Content type: Research

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  22. Anemia is very common in critical care patients, on admission (affecting about two-thirds of patients), but also during and after their stay, due to repeated blood loss, the effects of inflammation on erythrop...

    Authors: Sigismond Lasocki, Frédéric Pène, Hafid Ait-Oufella, Cécile Aubron, Sylvain Ausset, Pierre Buffet, Olivier Huet, Yoann Launey, Matthieu Legrand, Thomas Lescot, Armand Mekontso Dessap, Michael Piagnerelli, Hervé Quintard, Lionel Velly, Antoine Kimmoun and Gérald Chanques

    Citation: Annals of Intensive Care 2020 10:97

    Content type: Review

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  23. Prevalence of multiple organ failure (MOF) in critically ill patients is increasing and associated mortality remains high. Extracorporeal organ support is a cornerstone in the management of MOF. We report data...

    Authors: Valentin Fuhrmann, Theresa Weber, Kevin Roedl, Jasmin Motaabbed, Adel Tariparast, Dominik Jarczak, Aritz Perez Ruiz de Garibay, Johannes Kluwe, Olaf Boenisch, Harald Herkner, John A. Kellum and Stefan Kluge

    Citation: Annals of Intensive Care 2020 10:96

    Content type: Research

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  24. In critically ill patients, the use of high tigecycline dosages (HD TGC) (200 mg/day) has been recently increasing but few pharmacokinetic/pharmacodynamic (PK/PD) data are available. We designed a prospective ...

    Authors: Gennaro De Pascale, Lucia Lisi, Gabriella Maria Pia Ciotti, Maria Sole Vallecoccia, Salvatore Lucio Cutuli, Laura Cascarano, Camilla Gelormini, Giuseppe Bello, Luca Montini, Simone Carelli, Valentina Di Gravio, Mario Tumbarello, Maurizio Sanguinetti, Pierluigi Navarra and Massimo Antonelli

    Citation: Annals of Intensive Care 2020 10:94

    Content type: Research

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  25. There is no gold standard to diagnose septic shock-induced disseminated intravascular coagulation (DIC). The objective of our multicenter prospective study was to assess the performances of the different major...

    Authors: Julie Helms, François Severac, Hamid Merdji, Raphaël Clere-Jehl, Bruno François, Emmanuelle Mercier, Jean-Pierre Quenot and Ferhat Meziani

    Citation: Annals of Intensive Care 2020 10:92

    Content type: Research

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  26. Grown-up congenital heart (GUCH) patients represent a growing population with a high morbidity risk when undergoing reparative surgery. A main preoperative feature is right ventricular failure, which represent...

    Authors: Philippe Mauriat, Mirela Bojan, Sylvie Soulie, Hélène Foulgoc, Nadir Tafer and Alexandre Ouattara

    Citation: Annals of Intensive Care 2020 10:91

    Content type: Research

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  27. The present study aimed at comparing the success rate and safety of proximal versus distal approach for ultrasound (US)-guided axillary vein catheterization (AVC) in cardiac surgery patients susceptible to ble...

    Authors: Ying Su, Jun-yi Hou, Guo-guang Ma, Guang-wei Hao, Jing-chao Luo, Shen-ji Yu, Kai Liu, Ji-li Zheng, Yan Xue, Zhe Luo and Guo-wei Tu

    Citation: Annals of Intensive Care 2020 10:90

    Content type: Research

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  28. The impact on infectious risk of ultrasound guidance at insertion remains controversial in short-term arterial catheters (ACs). The present study investigated the association between ultrasound guidance (US) d...

    Authors: Niccolò Buetti, Stéphane Ruckly, Jean-Christophe Lucet, Lila Bouadma, Carole Schwebel, Olivier Mimoz and Jean-François Timsit

    Citation: Annals of Intensive Care 2020 10:89

    Content type: Research

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  29. Recirculation during veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a known drawback that limits sufficient oxygenation. This study aimed to compare the short-term oxygenation and long-term morta...

    Authors: Sung Yoon Lim, Soyeon Ahn, Sang-Bum Hong, Chi Ryang Chung, Kyeongman Jeon, Sang-Min Lee, Woo Hyun Cho, Sunghoon Park and Young-Jae Cho

    Citation: Annals of Intensive Care 2020 10:86

    Content type: Research

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  30. The endothelial glycocalyx comprises a complex layer of membrane-bound proteoglycans, secreted glycosaminoglycans, glycoproteins, glycolipids and bound plasma proteins such as albumin and antithrombin associat...

    Authors: Cesar Aldecoa, Juan V. Llau, Xavier Nuvials and Antonio Artigas

    Citation: Annals of Intensive Care 2020 10:85

    Content type: Review

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  31. The devastating pandemic that has stricken the worldwide population induced an unprecedented influx of patients in ICUs, raising ethical concerns not only surrounding triage and withdrawal of life support deci...

    Authors: René Robert, Nancy Kentish-Barnes, Alexandre Boyer, Alexandra Laurent, Elie Azoulay and Jean Reignier

    Citation: Annals of Intensive Care 2020 10:84

    Content type: Review

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  32. Limited data are available on the impact of a specialized extracorporeal membrane oxygenation (ECMO) team on clinical outcomes in patients with acute myocardial infarction (AMI) complicated by cardiogenic shoc...

    Authors: David Hong, Ki Hong Choi, Yang Hyun Cho, Su Hyun Cho, So Jin Park, Darae Kim, Taek Kyu Park, Joo Myung Lee, Young Bin Song, Jin-Oh Choi, Joo-Yong Hahn, Seung-Hyuk Choi, Jin-Ho Choi, Kiick Sung, Hyeon-Cheol Gwon, Eun-Seok Jeon…

    Citation: Annals of Intensive Care 2020 10:83

    Content type: Research

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  33. Recent guidelines advise against prophylactic antibiotics in patients with necrotizing pancreatitis, advocating instead a step-up drainage and necrosectomy strategy with antibiotics as dictated by microbiologi...

    Authors: Charlotte Garret, Emmanuel Canet, Stéphane Corvec, David Boutoille, Matthieu Péron, Isabelle Archambeaud, Aurélie Le Thuaut, Jean-Baptiste Lascarrou, Frédéric Douane, Marc Lerhun, Nicolas Regenet, Emmanuel Coron and Jean Reignier

    Citation: Annals of Intensive Care 2020 10:82

    Content type: Research

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  34. High-dose methotrexate (HD-MTX) is commonly used in the treatment of solid tumors and hematological malignancies. Severe toxicities are frequent, leading to organ dysfunction and death. Risk–benefit ratio of u...

    Authors: Sandrine Valade, Eric Mariotte, Elie Azoulay and Michael Darmon

    Citation: Annals of Intensive Care 2020 10:81

    Content type: Research

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  35. Endotoxins can induce an excessive inflammatory response and result in microcirculatory dysfunction. Polymyxin-B hemoperfusion (PMX-HP) has been recognized to effectively remove endotoxins in patients with sep...

    Authors: Shih-Hong Chen, Wing-Sum Chan, Chih-Min Liu, Ching-Tang Chiu, Anne Chao, Vin-Cent Wu, Wang-Huei Sheng, Chien-Heng Lai, Ming-Jiuh Wang and Yu-Chang Yeh

    Citation: Annals of Intensive Care 2020 10:80

    Content type: Research

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  36. Although many techniques have been introduced to facilitate nasogastric tube (NGT) insertion using anatomic landmarks and a group of devices, there is a lack of general consensus regarding a standard method. T...

    Authors: Sarvin Sanaie, Negin Mirzalou, Kamran Shadvar, Samad E. J. Golzari, Hassan Soleimanpour, Ali Shamekh, Deepti Bettampadi, Saeid Safiri and Ata Mahmoodpoor

    Citation: Annals of Intensive Care 2020 10:79

    Content type: Research

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  37. Aminoglycosides have a concentration-dependent therapeutic effect when peak serum concentration (Cmax) reaches eight to tenfold the minimal inhibitory concentration (MIC). With an amikacin MIC of 8 mg/L, the Cmax

    Authors: Elsa Logre, Maya Enser, Sébastien Tanaka, Marie Dubert, Aurore Claudinon, Nathalie Grall, Hervé Mentec, Philippe Montravers and Olivier Pajot

    Citation: Annals of Intensive Care 2020 10:75

    Content type: Research

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