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Research
Sepsis-related acute kidney injury (AKI) accounts for major morbidity and mortality among the critically ill. Heparin-binding protein (HBP) is a promising biomarker in predicting development and prognosis of s...
Annals of Intensive Care 2017 7:105
Published on: 18 October 2017
Research
Organ failure increases mortality in patients with liver cirrhosis. Data about resuscitated cardiac arrest patients with liver cirrhosis are missing. This study aims to assess aetiology, survival and functiona...
Annals of Intensive Care 2017 7:103
Published on: 6 October 2017
Research
In pressure-controlled (PC) ventilation, tidal volume (V T) and transpulmonary pressure (P L ) result from the addition...
Annals of Intensive Care 2017 7:100
Published on: 6 October 2017
Research
Quantitative and qualitative changes of skeletal muscle are typical and early findings in trauma patients, being possibly associated with functional impairment. Early assessment of muscle changes—as evaluated ...
Annals of Intensive Care 2017 7:104
Published on: 6 October 2017
Research
Elevated lactate concentration has been associated with increased mortality after out-of-hospital cardiac arrest (CA). We investigated the variables associated with high blood lactate concentrations and explor...
Annals of Intensive Care 2017 7:101
Published on: 6 October 2017
Research
Disruption of the endothelial glycocalyx contributes to acute lung injury in experimental sepsis but has not been well studied in humans. To study glycocalyx degradation in sepsis-induced ARDS, we measured pla...
Annals of Intensive Care 2017 7:102
Published on: 6 October 2017
Research
Acetaminophen (APAP)-induced acute liver failure (ALF) is associated with significant mortality due to intracranial hypertension (ICH), a result of cerebral edema (CE) and astrocyte swelling. Brain-type fatty ...
Annals of Intensive Care 2017 7:99
Published on: 5 October 2017
Research
Interstitial pneumonia with autoimmune features (IPAF) identifies a recently recognized autoimmune syndrome characterized by interstitial lung disease and autoantibodies positivity, but absence of a specific c...
Annals of Intensive Care 2017 7:98
Published on: 18 September 2017
Research
Prognostic scores and models of illness severity are useful both clinically and for research. The aim of this study was to develop two prognostic models for the prediction of long-term (6 months) and 28-day m...
Annals of Intensive Care 2017 7:96
Published on: 12 September 2017
Research
Venous thromboembolism (VTE) is one of the most common preventable causes of in-hospital death in trauma patients surviving their injuries. We assessed the prevalence, incidence and risk factors for deep venou...
Annals of Intensive Care 2017 7:97
Published on: 12 September 2017
Research
Active mobilization is not possible in patients under deep sedation and unable to follow commands. In this scenario, passive therapy is an interesting alternative. However, in patients with septic shock, passi...
Annals of Intensive Care 2017 7:95
Published on: 8 September 2017
Research
Echocardiographic myocardial dysfunction is reported commonly in sepsis and septic shock, but there are limited data on sepsis-related right ventricular dysfunction. This study sought to evaluate the associati...
Annals of Intensive Care 2017 7:94
Published on: 7 September 2017
Research
To analyse the usefulness of the composite index of the tissue inhibitor of metalloproteinases-2 (TIMP-2) and insulin-like growth factor-binding protein 7 (IGFBP7) as urinary biomarkers for the early predictio...
Annals of Intensive Care 2017 7:92
Published on: 7 September 2017
Research
Plasma concentrations of endocan, a proteoglycan preferentially expressed in the pulmonary vasculature, may represent a biomarker of lung (dys)function. We sought to determine whether the measurement of plasma...
Annals of Intensive Care 2017 7:93
Published on: 7 September 2017
Research
The soluble cluster of differentiation 14 (or presepsin) is a free fragment of glycoprotein expressed on monocytes and macrophages. Although many studies have been conducted recently, the diagnostic performan...
Annals of Intensive Care 2017 7:91
Published on: 6 September 2017
Research
Crush syndrome (CS) is a serious medical condition characterized by muscle cell damage resulting from decompression after compression (i.e., ischemia/reperfusion injury). A large number of CS patients develop ...
Annals of Intensive Care 2017 7:90
Published on: 4 September 2017
Research
Microvesicles (MV) are extracellular vesicles known to be associated with cellular activation and inflammation. Hemofiltration is an effective blood purification technique for patients with renal failure and p...
Annals of Intensive Care 2017 7:89
Published on: 4 September 2017
Research
Opioids and benzodiazepines are frequently used in the intensive care unit (ICU). Regular use and prolonged exposure to opioids in ICU patients followed by abrupt tapering or cessation may lead to iatrogenic w...
Annals of Intensive Care 2017 7:88
Published on: 2 September 2017
Research
Extracorporeal cardiopulmonary resuscitation (ECPR) has been considered in selected candidates with potentially reversible causes during a limited period. Candidate selection and the identification of predicta...
Annals of Intensive Care 2017 7:87
Published on: 30 August 2017
Research
Transpulmonary thermodilution is recommended in the treatment of critically ill patients presenting with complex shock. However, so far it has not been validated in hemodynamically stable patients with heart d...
Annals of Intensive Care 2017 7:86
Published on: 22 August 2017
Research
Blood purification is an emerging approach to dampening the cytokine storm. This study aims to assess the efficacy of HA330 resin-directed hemoadsorption (HA) on endotoxin-induced porcine acute respiratory dis...
Annals of Intensive Care 2017 7:84
Published on: 14 August 2017
Research
A decrease in circulating lymphocytes has been described as a marker of poor prognosis after septic shock; however, scarce data are available after cardiac arrest (CA). The aim of this study was to evaluate th...
Annals of Intensive Care 2017 7:85
Published on: 14 August 2017
Research
Some prior studies have shown that elevated mean central venous pressure in certain patient populations and disease processes may lead to poor prognosis. However, these studies failed to generalize the concept...
Annals of Intensive Care 2017 7:83
Published on: 9 August 2017
Research
Extracorporeal membrane oxygenation (ECMO) or pumpless extracorporeal lung assist (pECLA) requires effective anticoagulation. Knowledge on the use of argatroban in patients with acute respiratory distress synd...
Annals of Intensive Care 2017 7:82
Published on: 3 August 2017
Research
Neuromuscular blocking agents (NMBAs) have been shown to improve the outcome of the most severely hypoxemic, acute respiratory distress syndrome (ARDS) patients. However, the recommended dosage as well as the ...
Annals of Intensive Care 2017 7:79
Published on: 2 August 2017
