Neuromuscular blocking agents in patients with acute respiratory distress syndrome: a summary of the current evidence from three randomized controlled trials

Annals of Intensive Care

Table 4 Difference of physiological variables one day after the final of the NMBA infusion (72 hours)

	T0		T72		Change in Cisatracurium	Change in Control	p value ^*
	Cisatracurium	Control	Cisatracurium	Control
	(n= 223)	(n= 208)	(n= 223)	(n= 208)
PaO₂ / FiO₂	113.6 ± 14.1	119.6 ± 5.03	197.3 ± 32.0	165.6 ± 7.50	83.66 ± 35.92	46.00 ± 4.58	0.050
PaCO₂, mmHg	48.80 ± 2.09	47.20 ± 0.20	45.43 ± 1.35	44.76 ± 1.59	- 3.36 ± 1.97	- 2.43 ± 1.43	0.658
PEEP, cmH₂O	11.16 ± 2.00	10.36 ± 1.01	10.10 ± 0.81	10.50 ± 0.75	- 1.06 ± 1.22	0.13 ± 0.47	0.127
V_T, mL/kg	6.71 ± 0.33	6.96 ± 0.46	6.80 ± 0.34	7.00 ± 0.45	0.08 ± 0.02	0.04 ± 0.05	0.246
FiO₂, %	76.40 ± 5.39	71.76 ± 4.89	56.00 ± 1.00	59.00 ± 0.00	- 20.40 ± 5.57	- 12.76 ± 4.8	0.127

Positive end expiratory pressure; V_T: Tidal volume; FiO₂: Fraction of inspired oxygen; ICU: Intensive care unit.
^*: Mann-Whitney Exact Test.