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Annals of Intensive Care

Table 4 Difference of physiological variables one day after the final of the NMBA infusion (72 hours)

From: Neuromuscular blocking agents in patients with acute respiratory distress syndrome: a summary of the current evidence from three randomized controlled trials

  T0 T72 Change in Cisatracurium Change in Control p value *
Cisatracurium Control Cisatracurium Control
(n= 223) (n= 208) (n= 223) (n= 208)
PaO2 / FiO2 113.6 ± 14.1 119.6 ± 5.03 197.3 ± 32.0 165.6 ± 7.50 83.66 ± 35.92 46.00 ± 4.58 0.050
PaCO2, mmHg 48.80 ± 2.09 47.20 ± 0.20 45.43 ± 1.35 44.76 ± 1.59 - 3.36 ± 1.97 - 2.43 ± 1.43 0.658
PEEP, cmH2O 11.16 ± 2.00 10.36 ± 1.01 10.10 ± 0.81 10.50 ± 0.75 - 1.06 ± 1.22 0.13 ± 0.47 0.127
VT, mL/kg 6.71 ± 0.33 6.96 ± 0.46 6.80 ± 0.34 7.00 ± 0.45 0.08 ± 0.02 0.04 ± 0.05 0.246
FiO2, % 76.40 ± 5.39 71.76 ± 4.89 56.00 ± 1.00 59.00 ± 0.00 - 20.40 ± 5.57 - 12.76 ± 4.8 0.127
  1. Positive end expiratory pressure; VT: Tidal volume; FiO2: Fraction of inspired oxygen; ICU: Intensive care unit.
  2. *: Mann-Whitney Exact Test.
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