Figure 2
From: The transition from acute to chronic pain: might intensive care unit patients be at risk?
Cerebral structures involved in the descending modulation of nociceptive information. Amyg, amygdala; CX, cortex; DRG, dorsal root ganglion; DRT, dorsoreticular nucleus; Hypothal, hypothalamus; NA, noradrenaline; NTS, nucleus tractus solitarius; PAF, primary afferent fibre; PBN, parabrachial nucleus; PAG, periaqueductal grey; Perikarya 5-HT, serotonergic perikarya; PN, projection neurones; RVM, rostroventral medulla [30] (permission granted).